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Exercise 6 Liquid Dosage Form

The document outlines procedures for accurately measuring liquid volumes, emphasizing the importance of meniscus reading at eye level. It discusses factors affecting fill volume in pharmacy, tests for ensuring net content in semi-solid dosage forms, and lists various quality control tests for liquid dosage forms. Additionally, it highlights the significance of viscosity measurement in ensuring proper dosage form preparation and patient safety.

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9 views2 pages

Exercise 6 Liquid Dosage Form

The document outlines procedures for accurately measuring liquid volumes, emphasizing the importance of meniscus reading at eye level. It discusses factors affecting fill volume in pharmacy, tests for ensuring net content in semi-solid dosage forms, and lists various quality control tests for liquid dosage forms. Additionally, it highlights the significance of viscosity measurement in ensuring proper dosage form preparation and patient safety.

Uploaded by

pz.pizza
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Exercise 6: Liquid Dosage Form

Questionnaire:

1.Give the procedure for reading the volume in relation to the formation of meniscus.

1.​ Position the container on a level and even surface, then examine the level of the liquid.
2.​ To ensure accuracy, observe the volume by reading the measurement at the lowest or
highest point of concave or convex menisci, while keeping the observation at eye level.

Reference:

●​ Volumetric and graduated glassware. (n.d.).


https://www.vanderbilt.edu/AnS/Chemistry/courses/chem104/experiment1/volumetric/vol
umetric2.htm

2.What are the factors that may affect a product’s fill volume?

-​ Various factors, including the viscosity of the medication and the calibration of the
dispensing equipment, can affect the fill volume of a product in pharmacy. Moreover, the
dimensions and configuration of the receptacle can influence the precision of the
quantity being filled.

Reference:

●​ Filling bottles. (n.d.). E-PAK Machinery.


https://www.epakmachinery.com/blog/filling-bottles/

3.Discuss the test performed on semi-solid dosage forms to ensure accurate net content

-​ Tests are conducted to ascertain the net content of semi-solid dosage forms. Weight
uniformity testing guarantees the constancy of the dosage, content uniformity testing
assures the even distribution of the active component, and viscosity measurements
ensure the texture and spreadability of the product. These tests validate the quality and
effectiveness of the medication for patients.

Reference:

●​ Honeyman Group Limited - Laboratories. (n.d.). Uniformity assurance.


https://www.honeymanlaboratories.com/chemistry-testing/uniformity/

4. List down other tests performed on liquid dosage forms:

-​ Appearance and Color


-​ Odor and Taste
-​ Specific Gravity
-​ pH
-​ Viscosity
-​ Uniformity of Dosage Units
-​ Microbial Limits Testing
-​ Stability Testing
-​ Pourability and Dispersibility
-​ Dissolution Testing

Reference:

●​ Bista, N. (2023, March 14). Quality control tests of tablet. Pharma Info Nepal.
https://pharmainfonepal.com/quality-control-tests-of-tablet/

5. Give the significance of determining the viscosity of the liquids

-​ In the field of pharmacy, accurate measurement of liquid viscosity is essential for the
preparation of proper dosage forms such as suspensions, emulsions, and solutions that
possess optimal flow characteristics. Viscosity testing is used by quality control to
guarantee that products are consistent and safe for patients.

Reference:

●​ Viscosity Measurement | BYK Instruments. (n.d.).


https://www.byk-instruments.com/en/t/knowledge/viscometry-measurement

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