NIGERAIN ARMY SCHOOL OF MEDICAL SCIENCES
OJO CANTONMENT, LAGOS
DEPARTMENT OF PHARMACY TECHNICIANS
NCPE MOCK EXAM 2020
COURSE TITLE: BASIC DISPENSING THEORY
COURSE CODE: BDT352
TIME: 2HRS 30MINUTES
EXAM DATE: SEPT, 2020
INDEX NO:............................................................
INSTRUCTION: CHOOSE AN APPROPRIATE ANSWERS TO THE FOLLOWING 100
QUESTIONS WHICH CARRIES EQUAL MARKS
1. Aspects of Medicine which does not particularly Concerns Pharmacy profession
is ; (a) Preparation and Dispensing, (b) Diagnosis of illnesses , (c) Provision of
advisory role, (d) Drug Manufacturing Control Procedures.
2. Medication Dispensing does not include; (a) All activities involved in filling a
Prescription,(b) Supply of Medicines to hospital Wards, (c) Counseling Patients on
how to use Medication, (d) Synthesis of drug molecules
3. The "Art" of Preparation and Supply of Medicines is called
(a) Extemporaneous preparation, (b) Dispensing, (b) (c) Compounding,
(d) Drug Manufacturing
4. Knowledge required for “Good Dispensing Practice” includes; (a) Stability of
Medicine and their ingredients, (b) Legal requirements, (c) incompatibilities of
medicines, (d) All above
5. Forensic Pharmacy studies does not include; (a) Dispensing Records that must
be kept, (b) Containers selection and labeling, (c) Formulation methods, (d)
Conditions under which prescription can be dispensed
6. One of the Processes required for Extemporaneous medicine dispensing
includes; (a) Wearing freshly laundered overall coat, (b) Working in a clean and
tidy manner, (c) Understanding of the Prescription, (d) All the above
7. A written order from a Medical Practitioner for the supply of Medical product
to a patient is called; (a) Prescription,(b)Superscription
(c) Inscription, (d) Subscription
8. Information that makes a Prescription valid may not include;
(a) Patient's name and address, (b) The Prefix, (c) Names, Strengths and quantities
of ingredients or number of unit doses to be supplied, (d) Method of preparation.
9. One of these is not among the main "four parts" of a Prescription;
(a) The Recipe symbol, (b) Ingredients and their quantities, (c) Name of Patient,
(d) Prescribers signature.
10. Factor that alerts to possibility of a forged prescription includes.
(a) Known doctor's uncharacteristic prescribing method, (b) New patient with
unsigned Prescription, (c) Excessive altered quantities of medications, (d) All the
options
11. One of these may not be an intelligent information source for dispensing; (a)
British National formulary, (b) Martindale, (c) British Broadcasting Corporation; (d)
Pharmaceutical textbooks
12. Legally dispensed medicines may not be; (a) Products prepared by a Medical
Practitioner, (b) Products prepared in accordance with a Patient's description, (c)
Products prepared in accordance with a prescription, (d) Products prepared in a
registered pharmacy under supervision of a pharmacist.
13. One of these is not a Good Dispensing Practice; (a) Keeping dispensaries free
from disturbances, (b) Accumulation of apparatus and materials on benches, (c)
Ensuring clear sequence of events to prevent duplication or omission, (d) Special
vigilance to preclude mix up in labeling during simultaneous preparation of
medications
14. Factors that influences medication dosages may include; (a) Age and
Pathological state of Patient, (b) Dose frequency, (c) Route of drug administration,
(d) All the Options
15. One of the following expresses the 'Dose-volume' for Oral Liquids;
(a) Teaspoonfuls, (b) Desert spoonfuls, (c) 5ml-Spoonfuls, (d) Table spoonful
16. Auxiliary label is used for which of these purposes; (a) To amplify how
medicines are used , (b) To guide patients on storage conditions, (c) To indicates
the expiry date of medicines, (d) None of the options
17. Which of these is not an Auxiliary label: (a) Shake the bottle, (b) For External
use only, (c) Not to be taken, (d) Take Two-5ml Spoonfuls twice daily
18. One of these is not a desirable feature for pharmaceutical container
(a) Rigidity (b) Sorption of contents, (c) Closure prevent unintentional loss of
contents, (d) Elegance in appearance
19. One of these is not the main function of a Pharmaceutical container; (a)
Maintenance of contents quality, (b) Extension of expiry date of content, (c)
Maintenance of product safety, (d) Maintenance of contents stability.
20. Which of these is not an acceptable package for Tablets and Capsules, (a)
Paper bags, (b) Zip-lock plastic bags, (c) Tight-top tins
(d) Aluminum containers
21. Which of these is not an acceptable container for liquid products;
(a) Glass bottle with tight-fitting caps, (b) Plastic container with tight-fitting caps,
(c) Plastic-lined paper bags, (d) Glass or Plastic dropper in a protective container
22. Which of these is a disadvantage of glass containers; (a) Brittleness, (b)
Weightiness; (c) Alkali release to aqueous contents, (d) All the Options
23. An advantage of plastic over glass container include;
(a) More permeable to water vapor and atmospheric gasses, (b) More Sorption
effect, (c) Leaching of addictives into content, (d) Less brittle, lighter in weight and
more flexible
24. Which of these is not a Solid-dosage form; (a) Pessaries, (b) Effervescent
granules, (c) Suppositories, (d) pills
25. Topical semi-solid dosage forms does not include; (a) Jellies, (b) creams, (c)
Poultices, (d) Collodions
26. Which of these is not a Parenterals dosage form; (a) Injectables
(b) Irrigations, (c) Implants, (d) Infusions
27. Major Oral solid dosage forms may not include; (a) Tablets
(b) Capsules, (c) Powders, (d) Implants
28. Which of these is a disadvantage of Oral Solid dosage forms; (a) Promotion of
nausea and vomiting (b) Permits high accuracy of dosage
(c) Easy packaging due to small volume , (d) Minimized Loss of potency due to low
water content
29. One of the following is a Fundamental Operations for compounding
Medications; (a) Weighing (b) Measurement,(c) Mixing, (d) All the Options
30. Which weighing balance is not advised in weighing ingredients less than
100mg or 300mg for potent substances; (a) Using analytical balance, (b)
Triturating method, (c) Electronic balances, (d) Using a dispensing balance
31. Measurement errors in Liquid preparation results from which of the following;
(a) Meniscus Variation between water for calibration and the liquid measured, (b)
Graduation error, (c) Transference error,(d) All the options
32. Which of these methods of filtration doesn’t achieved higher degree of
clarification; (a) Straining; (b) Filter papers, (c) Sintered glass filters, (d) Cellulose
ester membranes
33. Heterogeneous Mixture does not include; (a) Two immiscible liquids, (b) Two
miscible and mobile liquids, (c) Insoluble solid in a liquid
(d) Insoluble solid and /or a liquid in a semi-solid base
34. Advantages of Pharmaceutical fine powders used in preparation may not
include (a) Uniformity of mixture, (b) Yields gritty preparations (c) Yields readily
absorbable product, (d) Soluble substances dissolves quickly.
35. which of these is not a method of "Size Reduction" in the dispensary, (a)
Mortar and Pestle dry grinding, (b) Wet grinding of paste with mortar and pestle,
(c) Levigation of paste with a large Spatula on tile, (d) Mixing with a stirrer in a
beaker
36. Size separation of powdered medicament is achieved by sifting, using which
one of these equipments; (a) Wire mesh sieves, (b) Stirrers, (c) Mortar and pestle,
(d) Tile and spatula
37. One of the following may not be an equipment used in dispensing of
medicine; (a) Tablet counting tray, (b) Mortar and pestle, (c) Tablet Machine, (d)
Measuring cylinder
38. Which of the following best expresses the meaning of "Medication expiry
date"; (a) Date a medication lost its shelf-life, (b) Date after which the
Manufacturer does not guarantee full potency,(efficacy) and safety of medication,
(c) Date at which drug has lost its potency, (d) Date at which a product has
deteriorated.
39.Which of these is not a proper way for disposing expired or unused drugs; (a)
Compliance with specific instructions on drug label for disposal, (b) To give friends
or relatives with similar symptoms for which drug was obtained, (c) Through
"Community take back program for recycling, (d) Flushing down toilet, or sink
40. The environmental concerns about improper drug disposal methods may
include; (a) Underground water pollution (b) Surface water pollution (c)
Protective Ozone layer depletion by Propellants, (d) All the options
41. The quantity of Sodium Chloride required to prepare 500ml 0.9% solution; (a)
0.9g, (b) 4.5g, (c) 5.5g, (d) 9g
41.What volume of 95% Alcohol will be used to prepare 600ml of 60% Alcohol; (a)
450ml, (b) 379ml, (c) 300ml, (d) 279ml
42. What is the Conc. of 100ml Potassium Permanganate solution, of which 1part
diluted with 7parts of water yields 1 in 8000 solution;(a) 0.2%W/V, (b) 0.3%W/V,
(c) 0.1%W/V, (d) 0.15%W/V
43. Which of these is a Good Storage Condition for Suspensions; (a) Refrigerator,
(b) Extreme variations in temperatures, (c) In a cool place
(d) Deep freezer
44. Thickening agent used for stabilizing Suspensions may include one of the
following; (a) Acacia gum, (b) Methylcellulose, (c) Bentonite, (d) All the options
45. Auxiliary labels required for External Suspension dosages may include one of
these; (a) "Shake the bottle", (b) Apply at affected parts
(c) "For External use only", (d) a and c
46. Which of the following is the most commonly used solid-dosage forms; (a)
Hard Capsules, (b) Tablets, (c) Soft Capsules, (d) powders
47. One of the following is not the purpose for the granulation of powders; (a) To
improved the flow properties of particles in the mixture, (b) To Increase the ability
to bind under pressure, (c) To Prevent segregation of components powder
mixture, (d) For preservation
48.Which of these is not one of the excipients for tablet production:
(a) Diluents, (b) Disintegrant, (c) Glidants, (d) Emulsifier
49. One of these is a Semi-Solid dosage form administered via the rectum for
either local of systemic effect; (a) Pessaries, (b) Tablets, (c) Suppositories, (d)
Ovules
50. Characteristic of an ideal Suppository basis includes ;(a) To Melt, deform or
dissolve at body temperature, (b) Possesses non-irritant or sensitizing property,
(c) Readily molded into stable rigid shapes, (d) All the options
51 Which of the following products is not a Mixture; (a) Dusting powder, (b)
Calamine Lotion, (c) Magnesium Trisilicate(d) None of the options
52. Factors that ensures accurate and reproducible dosage of Suspension may not
include; (a) Uniformly small sized particles
(b) Suspending agents, (c) Lubricating agents, (d) Viscosity enhancing agents.
53. Which of these is not essential as a vehicle for Oral liquid preparations; (a)
Aromatic Waters, (b) Pyrogen free water , (c) Water for preparation, (d) Syrups
54. Excipients for Oral liquid preparations does not include ; (a) Lubricants , (b)
Preservatives, (c) Antoxidant, (d) Flavoring agents.
55. Prescription drug label may be referred to as; (a) Package insert
(b) Package Circular, (c) Direction Circular, (d) All the options
56. Which of these is the "Primary purpose" of a Prescription drug Label; (a) To
Manage risk and minimize adverse events in product use, (b) To Direct patients on
when and how to use product, (c) For Concise information to health professionals
on safe and effective use of drug, (d) All above
57. What is the life span of a diluted cream, (a) 2 weeks from the date of issue,(b)
1 Month from the date of issue, (c) 1 Week from date of issue, (d) 3 Months from
date of issue
58. Consequences of diluted creams with unsuitable diluents includes; (a) Altered
release rate of active ingredient, (b) Breakdown or inactivation of active
ingredient, (c) Bacterial contamination due to incompatibility of preservative and
diluents, (d) All the options
59. A suspension contains 120mg of paracetamol in each 5ml, find the volume of
Suspension that contains 300mg of paracetamol; (a) 16.5ml, (b) 12.5ml, (c)
10.5ml, (d) 20.5ml.
60. The recommended dose of phenytoin for a patient is 840mg, what volume of
injection containing 50ml/ml is required for the above dose; (a) 15ml (b) 28.8ml,
(c) 38.5ml (d) 16.8ml
61. 25g of Ointment contains 5g of calamine, how much calamine will be
contained in 60g Ointment.(a) 12g (b) 15g, (c) 30g (d) 30g
62. 2L of an aqueous solution contains 50ml of ethanol. Express this as a ratio
strength; (a) 1 in 50 v/v , (b) 1 in 80 v/v (c) 1 in 40 v/v (d) 1 in 40 w/w
63. A Cream contains 12g of an active ingredient (drug X) made up to 100g with
cream base. What is the percentage concentration?(a) 10% v/v, (b) 12%w/v,(c)
12% w/w, (d) 10%w/v.
64. A solution contains 20ml of ethanol in 500ml of product. Express the
concentration as ratio strength and as percentage strength;
(a) 1 in 25v/v or 4%v/v, (b) 1 in 2v/v or 3%v/v, (c) 1 in 8w/v or 8%w/v
(d) 1 in 12w/w or 12%w/w
65. 1L of aqueous solution contains 250ml of syrup. What quantity of syrup will be
contained in 25L of solution; (a) 6.25L (b) 62.55ml (c) 38,250ml, (d) 108ml.
66. In a solid dosage form, 2g of a solid active ingredient is contained in 500g of
the product. If this product is diluted with a further 250g of the vehicle, what is
the total weight of the product ;(a) 650g, (b) 750g, (c) 380g, (d) 450g
67. A child's prescription is 2ml of an analgesic suspension three times daily for
4/7. What volume of the drug will be dispensed: (a) 24ml, (b) 20ml, (c) 22.4ml, (d)
14ml
68. A prescription requires two suppositories of drug Y daily for 3/7. How many
suppositories should be supplied; (a) 2 , (b) 6, (c) 5, (d) 10.
69. Appropriate storage condition for Syrup may not include;
(a)At Constant temperature, (b) In a Well-closed Container, (c) In diluted form (d)
In concentration of 66.7%w/w
70. Temperature fluctuation in storage of Syrup may cause one of the following
instabilities ; (a) Crystallization, (b) Fermentation (c) Multiplication of Micro-
organism (d) Dilution.
71. Which of the following is the correct characteristic of an Elixir
(a) Clear product, (b) Powder or granule for reconstitution, (d) Palatable and
stable (d) All the options
72. At what conditions can Pediatric drops be used as medication form; (a)
Products that are seriously affected by dilution, (b) In all children's preparations,
(c) When larger doses are inappropriate like in infants, (d) a and c
73. Types of Oral liquid preparations may not include; (a) Oral solids for
reconstitution, (b) Emulsions, (c) Suspensions, (d) All the options
74. Which of the following is not a disadvantage of Liquid preparation ;
(a) Less Stable, (b) Susceptible to Microbial contamination, (c) Reduced gastric
irritation, (d) Difficulty in masking unpleasant taste.
75. Types of emulsions may include; (a) Oil dispersed in water, (b) Water
dispersed in Oil, (c) Liquid dispersed in semisolid base, (d) All the options
76. Reasons for administering o/w type of Emulsions orally may include one of the
followings; (a) To disguise the taste (b) To disguise the oiliness of the drug, (c) To
improve absorption of oils, (d) all the options
77. In which of these ways are liquid emulsions not used; (a) Orally, (b)
Parenterally, (c) Externally, (d) None of the options
78. Classes of o/w or w/o Liquid emulsions for external use may not include; (a)
creams, (b) Applications, (c) Lotions, (d) Liniments
79.Which of these is not a reason why preparations of o/w are superior to w/o
emulsions; (a) They rub into skin more readily (b) Easily removed by washing (c)
More likely to soil clothes, (d) Evaporation of aqueous phase causes cooling.
80. Which of these is a none sterile dosage form; (a) Implants, (b) Eye drops, (c)
Oral liquid products (d) injections
81. Advantages of Parenteral route of drug administration may not include; (a)
Induces nausea and vomiting (b) Safe and effective in unconscious patients (c)
Enhances control of drug regimen aiding compliance, (d) Rapid and effective
response in emergency.
82. Which of these containers is suitable for Parenteral preparations;
(a) Ampoules (b) Vials (c) Polyvinyl chloride bags (d) All the options
83. Which is an advantage of Ampoule containers over Vials for Parenterals; (a)
high speed filling than vials, (b) sealing at point of production reducing
contamination, (c) Laceration of finger while opening, (d) Aseptically prepared
84. Aseptic processing of Parenteral products involves;
(a) Transfer and sealing operation, (b) Formulation using sterile components, (b)
Clean room technology, (c) Sterilization of equipments and finished products
either thermally or using bacteria proof filter, (d) all the options
85. Possible causes of deterioration of Medications during storage does not
includes; (a) Prolonged storage, (b) Extremes of temperature, (c) Effects of Light
(d) Use of Required storage conditions by manufacturer.
86. Which of these products does not require storage in a refrigerator; (a) Oral
liquid antibiotics, (b) Powdered dosages (c) Insulin injections, (d) Diagnostic
Agents.
87. Guide to "Good Dispensing Practice" for storage of medicine may not include;
(a) Materials being stored under recommended conditions, (b) Stock storage near
toilet areas, (c) Storage and issuance of drugs in chronological sequence, (d)
Store keeper exercising full knowledge of stability of material to remove expired,
deteriorated or over stayed products.
88. Drugs requiring cold chain distribution methods may not include;
(a) Insulin, (b) Vaccines (c) Cytotoxic products (d) Oral antibiotics
89. Indications of deterioration of a solid dosages may include; (a) Excessive
moisture, (b) Swelling, (c) Discoloration, (d) All the options.
90. Instability of Oral Liquid Solution may not include; (a) Caking, (b) Turbidity, (c)
Gas formation, (d) Precipitation.
91. Major areas of Quality assurance in pharmaceutical production excludes; (a)
Quality control, (b) Production, (c) Distribution, (d) None of the options
92. Quality analysis applies to which of these production processes; (a)
Preproduction testing, (b) In-production testing, (c) Post-production testing, (d) all
the options
92. Types of analysis carried out by Quality control include;
(a) Raw material identification, (b) Bacterial identification, (c) Sampling,
specification and testing of both raw and finished products, (d) All the options.
93. Which of these medicinal products is unstable for freezing; (a) Emulsions, (b)
Suspensions, (c) Insulin (d) All the options.
94. Which of these is not true for a "Recently Prepared" Mixtures; (a)To be
stored not more than three months (b) Not to be made more than a few days
before issue, (c) Discard Unused parts after one month from date of issue, (d) Not
to be stored longer than a few weeks under temperate room conditions.
95. Which of these statements is correct about "Freshly Prepare" Mixtures; (a)
Particularly unstable Mixtures, (b) Discard two days from date of issue, (c) Expiry
date is Two days after the date the last dose should have been taken, (d) Must be
prepared not more than 24 hours before issue.
96. Which statement about the "Dilution of mixtures" is not correct;
(a) Reduces the stability of mixture, (b) To be carried out immediately before
issue to patient, (c) Water to be used as diluents, (d) Not more than two weeks
supply to be dispensed.
97. Method for converting medicinal powders into free flowing granules may not
includes; (a) Dry granulation process, (b) Moist granulation process, (c) Blending
process, (d) None of the options
98. Which of these is the function of a "Disintegrant" in tablet formulation; (a) To
increase the bulk of tablet, (b) To prevent crumbling of granules into powders, (c)
Ensures breakup of tablets in stomach, (d) Improves flow properties of granules
99. Which of the GMP precaution is required for Manufacturing personnel; (a)
Medical examination to exclude persons with infectious diseases, (b) Use of
appropriate protective garments within production area, (c) Prohibition of storage
of consumable items in production areas, (d) All the options
100. Which of these is not a common source of preventable medication error; (a)
Ignoring prescription labels, (b) None Compliance to instruction by Patient, (c)
Crushing extended release drug,(d) Application of Good Dispensing Practice by
trained Pharmacist