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Alcohol Poisoning: DR Bilal Iqbal

This document discusses different types of alcohols that can cause poisoning when ingested, including ethanol, methanol, isopropanol, and ethylene glycol. It provides details on ethanol, the most commonly ingested alcohol, including its sources and methods for analysis in blood and breath samples. Isopropanol is the second most common alcohol ingested and its sources and analysis are also outlined. Methanol sources are listed.

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dr. SheryarOrakzai
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44 views12 pages

Alcohol Poisoning: DR Bilal Iqbal

This document discusses different types of alcohols that can cause poisoning when ingested, including ethanol, methanol, isopropanol, and ethylene glycol. It provides details on ethanol, the most commonly ingested alcohol, including its sources and methods for analysis in blood and breath samples. Isopropanol is the second most common alcohol ingested and its sources and analysis are also outlined. Methanol sources are listed.

Uploaded by

dr. SheryarOrakzai
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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ALCOHOL

POISONING
Dr Bilal Iqbal
ALCOHOL
 Ethanol
 Methanol
 Isopropanol
 Ethylene glycol
ETHANOL
Most commonly ingested alcohol.
ETHANOL SOURCES
 Alcoholic drinking
 Colognes
 Medical preparation
 Mouthwashes
ANALYSIS OF ETHANOL
 Blood Ethanol  Breath Ethanol
 Enzymatic analysis :  Breath alcohol measurement devices use :

 Ethanol is measured by oxidation to  Infrared abrorption spectrometry


acetaldehyde with NAD a reaction is  Dichromatic sulfuric acid oxidation
catalyzed by ADH , NADH is measured at reduction (photometric)
340 nm that is proportional to Ethanol
present.  Electrochemical oxidation

 Serum or plasma is preferred over whole


blood to prevent interference from
hemoglobin.
ISOPROPANOL
(SECOND MOST COMMONLY INGESTED ALCOHOL)
Sources :
Industry solvent
Disinfectant
Skin and hair products
Jewelry cleaners
Detergents
Paint thinners
Anti freeze
ISOPROPANOL ANALYSIS
 Isopropanol and its metabolite Acetone determined by
 Headspace gas chromatography
 Nuclear magnetic resonance
METHANOL
 Sources:
 Solvent in commercial products
 Constituent of antifreeze and window cleaning fluids
 Componrnt of canned fuel

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