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Prevention is a challenge in younger patients; it’s near impossible in older patients
Yet another study reveals the challenge of mechanical stroke prevention techniques, such as left atrial appendage closure, when applied to older…
15 hrs ago
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John Mandrola
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The Ghost Patient Panel
Friday Reflection 23 Revisited
Jan 2
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Adam Cifu, MD
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97
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34
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1:22:34
This Fortnight in Medicine XVI
Finishing up our AUA questions.
Dec 31, 2025
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Adam Cifu, MD
,
John Mandrola
, and
Andrew J Foy
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The COVID Vaccine in Young Children Is Not as Effective as the Headlines Would Have You Believe
COVID in kids made the news recently.
Dec 30, 2025
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Edward H Livingston, MD, FACS
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141
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Prediction is Hard Especially About the Future
Cardiac risk scores can be useful for populations but not so much for you.
Dec 29, 2025
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John Mandrola
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129
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For Christmas, A Gift of Laughter
...and a writing and editing break for me.
Dec 26, 2025
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Adam Cifu, MD
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80
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Holidays in the Hospital
It’s a common sentiment that working on a holiday is terrible but...
Dec 25, 2025
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Rachel Johnson
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270
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61
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21
The Embarrassing but Necessary Lesson in a Drug Removal From the Market
Nearly everyone but Vinay Prasad was wrong about the Factor Xa reversal agent.
Dec 22, 2025
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John Mandrola
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186
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38
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The Ethics of PSA Testing and Cancer Screening
Is choosing to undergo a screening like buying a lottery ticket in that you will not benefit, but you are helping someone else who might?
Dec 19, 2025
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Adam Cifu, MD
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Climbing Out of the Trenches: Rethinking Polarisation in Medicine
We can choose to keep fighting from our ideological trenches—or we can collectively climb out of them. The path forward lies in recognising shared aims…
Dec 18, 2025
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Elspeth Davies
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103
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30
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This Fortnight in Medicine XV
A first foray into the "ask us anything" questions
Dec 17, 2025
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Adam Cifu, MD
,
John Mandrola
, and
Andrew J Foy
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1:00:39
Heart Failure in Trials vs Heart Failure in the Average Hospital/Clinic
I was misunderstood on the Internet. Here is my explanation: it has to do with the (minimally disruptive) treatment of patients with heart failure
Dec 15, 2025
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John Mandrola
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