- current flagship projects (Bio-LLM Evaluation Suite, Vision-Language-Action Lab Robotics, Comparative Agentic Research Platform),
- open-source contributions in computational biology ecosystems (Galaxy Project, MAIA, mAIstro, Cognitive Kernel-Pro, Prime Intellect),
- communication assets (lab reports, demos, newsletters),
- and the operational cadence that demonstrates consistent research velocity.
Advance safe, reproducible, and equitable AI systems for life science and healthcare by bridging modern frontier-model capabilities with rigorous bioinformatics practice.
- Multimodal AI for Life Sciences: Vision-language-action pipelines for wet-lab automation, pathology, radiomics, and multi-omics decision support.
- Scalable MLOps & Evaluation: GPU-accelerated genomic workflows, benchmark harnesses, GAIA-style agentic evaluations, and reproducible research infrastructure.
- Responsible Deployment: Privacy-first data handling, HIPAA-aligned pipelines, secure audit trails, and transparent documentation for clinical stakeholders.
| Project | Focus | Status | Next Milestone |
|---|---|---|---|
| Bio-LLM Evaluation Suite | Fine-tuning + safety benchmarking of open models on curated clinical & genomic corpora with encrypted audit trails | Planning | Design architecture & dataset audit by 20 Oct 2025 |
| Vision-Language-Action Lab Robotics | Helix-inspired controllers for automated pipetting/assay workflows with simulation-to-reality transfer | Planning | Build simulation environments & baseline policy by 03 Nov 2025 |
| Comparative Agentic Research Platform | Galaxy + Cognitive Kernel-Pro integration for pathogen surveillance experiments with agent decision logging | Planning | Draft integration proposal & open initial issues by 27 Oct 2025 |
| Project | Contribution Track | Issue/PR Goal (Oct–Dec) |
|---|---|---|
| Galaxy Project | GPU-accelerated genomics tools, reproducible Jupyter tutorials, blog on workflow reproducibility | ≥2 merged PRs + 1 co-authored blog |
| mAIstro | Extend agent orchestration to omics datasets, add automated evaluation harnesses, publish benchmarks | ≥1 agent orchestration PR + benchmark report |
| MAIA | Kubernetes Helm charts, HIPAA-aligned data pipeline docs, clinician feedback sprint | Helm chart merge + sprint facilitation notes |
| Cognitive Kernel-Pro | Biomedical reasoning tasks, GAIA-aligned evaluation suites, reflection note | Eval suite PR + reflection technical note |
| Prime Intellect INTELLECT-3 | Decentralized RL environments for genomics optimization, leaderboard support | RL environment PR + leaderboard integration |
Progress will be tracked via project boards and weekly lab reports (see docs/lab-reports/).
- Fortnightly Lab Reports: Summaries of code contributions, experiments, benchmarks, and learnings. (Template in
templates/lab-report.md) - Demo Videos: ≤3 minute walkthroughs for each major PR, embedded into project README badges.
- Monthly Newsletter: “Top 5 AI/Bio Papers & Repos” highlighting contributions and community insights.
- Changelog: Running catalogue of merged PRs, metrics, and community feedback (see
CHANGELOG.md).
- Refresh GitHub profile README, pinned repositories, and contribution graph screenshots.
- Launch a public project board outlining experiments, benchmarks, and writing tasks.
- Submit introductory outreach messages to Galaxy, MAIA, and Cognitive Kernel-Pro maintainers (templates in
templates/outreach/). - Scope Bio-LLM Evaluation Suite architecture and dataset risk assessment.
- Log first lab report draft covering kickoff activities and initial community touchpoints.
src/bio_llm_eval/— Python package scaffolding (data loaders, training/evaluation placeholders, CLI entry point).configs/pubmedqa.baseline.json— Sample configuration for the baseline pipeline.docs/— Design docs, dataset notes, issues, lab reports.templates/— Outreach and lab-report templates.tools/compliance/— PHI scanning utility for dataset onboarding.tests/— Pytest smoke tests validating scaffolding.
Run the placeholder pipeline:
python -m bio_llm_eval.cli --config configs/pubmedqa.baseline.json --report reports/baseline.jsonThe command currently operates in dry-run mode (no model download). Setting "dry_run": false triggers full LoRA-capable fine-tuning when a GPU is detected; if no GPU is available the runner automatically falls back to dry-run mode and logs a warning.
Optional flags:
python -m bio_llm_eval.cli \
--config configs/pubmedqa.baseline.json \
--append-changelog \
--changelog-path CHANGELOG.md \
--append-lab-report \
--lab-report-path docs/lab-reports/2025-10-13.mdThis appends a bullet summarising accuracy, toxicity, and hallucination heuristics to the specified changelog / lab report after the run.
python -m venv .venv
source .venv/bin/activate
pip install --upgrade pip
pip install -e .[dev]
pytestRefer to CONTRIBUTING.md for full workflow details (linting, compliance steps, submission guidelines).
make lint/make test/make run-sampleprovide convenient wrappers for common tasks.- GitHub Actions workflow (
.github/workflows/ci.yml) runs lint, tests, and the dry-run pipeline across Python 3.9–3.11 on every push/PR.
data/samples/pubmedqa.sample.jsonl— minimal 3-example slice used for tests and dry-run validation. Replace with the approved dataset path after completing the compliance checklist indocs/checklists/completed/.
batch_size,gradient_accumulation_steps— control training throughput for the LoRA pipeline.lora.enable— toggle PEFT LoRA adapters; targeting modules configurable.dry_run— Skip model downloads; automatically overridden toTrueif no GPU is detected.
MIT License to encourage collaboration while protecting sensitive datasets and proprietary assets.