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@parklab Park Lab at Harvard Medical School

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    48 repositories

    • SMaHT_SNV_COLO829BLT50_HAPMAP

      Public
      Jupyter Notebook
      •1•0•1•1•Updated Feb 25, 2026Feb 25, 2026

    • parklab.github.io

      Public
      HTML
      •1•0•0•0•Updated Feb 23, 2026Feb 23, 2026

    • SMaHT_Regional_Categorization

      Public
      This repository has the description of the hg38 genome categorization of easy, difficult, and extreme region.
      0•1•0•0•Updated Feb 18, 2026Feb 18, 2026

    • SMaHT_Tissue_Benchmark_SmallVariants

      Public
      0•0•0•0•Updated Feb 3, 2026Feb 3, 2026

    • KidsFirst_TE_pediatric_cancer

      Public
      R
      •0•0•0•0•Updated Jan 29, 2026Jan 29, 2026

    • denovo_retroelements_kids_first

      Public
      Python
      •0•0•0•0•Updated Jan 9, 2026Jan 9, 2026

    • NanoSeq_parkLab

      Public
      Analysis software for Nanorate Sequencing (NanoSeq) experiments -- forked over from Sanger Institute
      C++
      •
      GNU Affero General Public License v3.0
      •15•0•0•0•Updated Dec 16, 2025Dec 16, 2025

    • MosaicForecast

      Public
      A mosaic detecting software based on phasing and random forest
      Python
      •
      MIT License
      •21•70•7•2•Updated Dec 8, 2025Dec 8, 2025

    • code-share

      Public
      Repository to host shared code for the lab
      Shell
      •0•0•0•0•Updated Nov 10, 2025Nov 10, 2025

    • EchoSV

      Public
      A novel tool for accurately merging haplotype-based SV calls and comparing SVs across reference genomes
      cross-referencegenotypingsv-mergingsv-comparison
      Python
      •
      MIT License
      •0•6•0•0•Updated Oct 9, 2025Oct 9, 2025

    • spatial_sampling_analysis

      Public
      This repository contains analysis of spatially-resolved somatic mutations datasets.
      HTML
      •
      MIT License
      •0•1•0•0•Updated Sep 17, 2025Sep 17, 2025

    • r-scan2

      Public
      R package supporting the SCAN2 pipeline
      R
      •4•0•1•0•Updated Aug 26, 2025Aug 26, 2025

    • HiScanner

      Public
      C
      •
      MIT License
      •2•8•1•0•Updated Aug 13, 2025Aug 13, 2025

    • bamsnap

      Public
      HTML
      •
      MIT License
      •27•124•20•0•Updated Aug 1, 2025Aug 1, 2025

    • SPECIFICANCER_data

      Public
      JavaScript
      •
      MIT License
      •0•0•0•0•Updated Jul 30, 2025Jul 30, 2025

    • SCAN2

      Public
      SCAN2 is a somatic SNV and indel genotyper for single cells amplified by Primary Template-Directed Amplification (PTA)
      Python
      •9•17•16•1•Updated Jul 28, 2025Jul 28, 2025

    • ViScanner

      Public
      Scanner output visualization tool
      JavaScript
      •0•0•0•0•Updated Jul 15, 2025Jul 15, 2025

    • r-mutenrich

      Public
      Analyze distribution of somatic mutations with permutations as a background
      R
      •0•0•0•0•Updated Jul 7, 2025Jul 7, 2025

    • xTea

      Public
      Comprehensive TE insertion identification with WGS/WES data from multiple sequencing technics
      nanoporepacbioilluminatransposable-elementslinked-readsmobile-element-insertion
      Python
      •
      Other
      •23•120•13•2•Updated Jul 4, 2025Jul 4, 2025

    • hiscanner_demo

      Public
      MIT License
      •1•2•1•0•Updated Jul 1, 2025Jul 1, 2025

    • NMF_jointMU

      Public
      Jupyter Notebook
      •
      MIT License
      •0•0•0•0•Updated May 29, 2025May 29, 2025

    • Salamander

      Public
      Salamander is a non-negative matrix factorization framework for signature analysis
      Python
      •
      MIT License
      •0•9•0•0•Updated Aug 30, 2024Aug 30, 2024

    • SigMA

      Public
      Mutational signature analysis for low statistics SNV data
      R
      •
      Other
      •22•64•11•0•Updated Aug 7, 2024Aug 7, 2024

    • MuSiCal

      Public
      A comprehensive toolkit for mutational signature analysis
      Python
      •
      Other
      •7•41•11•0•Updated Jul 19, 2024Jul 19, 2024

    • NGSCheckMate

      Public
      Software program for checking sample matching for NGS data
      Python
      •
      MIT License
      •57•137•29•4•Updated Jun 20, 2024Jun 20, 2024

    • MSIprofiler

      Public
      Repo that aids in the detection of microsatellite instabilities (MSI) from sequencing data
      Python
      •4•21•0•3•Updated Apr 22, 2024Apr 22, 2024

    • luquette-glia-analysis

      Public
      Scripts for the glia project
      R
      •0•0•1•0•Updated Mar 6, 2024Mar 6, 2024

    • focal-amplification

      Public
      R
      •3•7•0•0•Updated Oct 23, 2023Oct 23, 2023

    • SVA_catalog

      Public
      Host the SVA reference catalog
      JavaScript
      •0•0•0•0•Updated Sep 16, 2023Sep 16, 2023

    • SVA_landscape_project

      Public
      HTML
      •0•0•1•0•Updated Sep 16, 2023Sep 16, 2023