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đź“– A collection of pure bash alternatives to external processes.

Shell 41,183 3,626 Updated Nov 28, 2023

An Artificial Neural Network-based discriminator for validating clinically significant genomic variants

Python 35 6 Updated Dec 25, 2023

Python and C++ code for reading and writing genomics data.

C++ 799 120 Updated Dec 9, 2021

This repository holds the companion project to Goby3, used to train and evaluate deep learning models to call variations. This repository contains the Matcha framework to help train and evaluate de…

Java 51 20 Updated Jun 1, 2018

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

Python 3,604 767 Updated Oct 21, 2025

RUFUS k-mer based genomic variant detection

C++ 54 14 Updated Jan 5, 2026

⛔️ DEPRECATED – See https://github.com/ageron/handson-ml3 instead.

Jupyter Notebook 25,844 12,865 Updated Oct 3, 2023

Data science Python notebooks: Deep learning (TensorFlow, Theano, Caffe, Keras), scikit-learn, Kaggle, big data (Spark, Hadoop MapReduce, HDFS), matplotlib, pandas, NumPy, SciPy, Python essentials,…

Python 28,832 8,047 Updated Mar 20, 2024

A toolkit to learn how to model and interpret regulatory sequence data using deep learning.

Jupyter Notebook 264 67 Updated Aug 1, 2023

Fast, flexible and easy to use probabilistic modelling in Python.

Python 3,509 596 Updated Mar 6, 2025

Deep neural networks for predicting CpG methylation

Python 37 13 Updated Apr 11, 2017
Jupyter Notebook 872 418 Updated Dec 6, 2016

Convolutional neural network analysis for predicting DNA sequence activity.

Jupyter Notebook 267 107 Updated Sep 14, 2020

Python Data Science Handbook: full text in Jupyter Notebooks

Jupyter Notebook 46,611 18,682 Updated Jun 26, 2024

📝 An awesome Data Science repository to learn and apply for real world problems.

28,181 6,357 Updated Jan 25, 2026

Approximate Nearest Neighbor Search for Sparse Data in Python!

Python 919 143 Updated Oct 2, 2020

A Python Automated Machine Learning tool that optimizes machine learning pipelines using genetic programming.

Jupyter Notebook 10,043 1,578 Updated Sep 11, 2025

Python interface to access reference genome features (such as genes, transcripts, and exons) from Ensembl

Python 399 70 Updated Aug 13, 2025

Recipes for using Python's pandas library

Jupyter Notebook 6,997 2,363 Updated Oct 24, 2024

Luigi is a Python module that helps you build complex pipelines of batch jobs. It handles dependency resolution, workflow management, visualization etc. It also comes with Hadoop support built in.

Python 18,632 2,449 Updated Jan 23, 2026

Curated decibans of scientific programming resources in Python.

Julia 1,019 194 Updated Jul 4, 2023

The CHM1-NA12878 benchmark for single-sample SNP/INDEL calling from WGS Illumina data

JavaScript 32 5 Updated Feb 20, 2018

High throughput, pain-free big data pipelines.

Python 30 7 Updated Mar 11, 2017

bedtools - the swiss army knife for genome arithmetic

C 1,020 296 Updated Mar 11, 2025

C library for high-throughput sequencing data formats

C 900 459 Updated Jan 22, 2026
Jupyter Notebook 36 13 Updated Sep 6, 2017

A curated list of awesome big data frameworks, ressources and other awesomeness.

14,174 2,595 Updated Nov 27, 2025
Java 301 85 Updated Dec 12, 2025

Code and examples for JHU Computational Genomics class

Jupyter Notebook 306 112 Updated Oct 22, 2024

Flexible and powerful data analysis / manipulation library for Python, providing labeled data structures similar to R data.frame objects, statistical functions, and much more

Python 149 27 Updated Aug 8, 2019
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