- VALENTINE, LEWIS EDWARD (1893 - 1986), Baptist minister, author and Welsh nationalist
- VAN HEYNINGEN, RUTH ELEANOR (1917 - 2019), biochemist
- VARRIER-JONES, PENDRILL CHARLES (1883 - 1941), physician
- VAUGHAN family Golden Grove,
- VAUGHAN family Hergest, Kington
- VAUGHAN family Llwydiarth,
- VAUGHAN family Tretower Court,
- VAUGHAN family Corsygedol,
- VAUGHAN family Bredwardine,
- VAUGHAN family Courtfield,
- VAUGHAN family Clyro,
- VAUGHAN family Trawsgoed, Crosswood,
- VAUGHAN family Porthaml,
- VAUGHAN family Pant Glas,
- VAUGHAN, Maesyneuadd Llan-decwyn - see WYNN
- VAUGHAN, Nannau - see NANNAU
- VAUGHAN, Dunraven - see EDWIN
- VAUGHAN, Dunraven - see VAUGHAN
- VAUGHAN, Caerynwch - see RICHARDS
- VAUGHAN, ARTHUR OWEN (Owen Rhos-comyl; 1863? - 1919), adventurer and author
- VAUGHAN, BENJAMIN NOEL YOUNG (1917 - 2003), Anglican priest
- VAUGHAN, EDWARD (d. 1661), Master of the Bench of the Inner Temple
- VAUGHAN, EDWARD (d. 1522), bishop of S. Davids
- VAUGHAN, EDWARD, rector - see VAUGHAN, ROWLAND
- VAUGHAN, EDWIN MONTGOMERY BRUCE (1856 - 1919), architect
- VAUGHAN, Sir GRUFFUDD (d. 1447), soldier
- VAUGHAN, GWYNETH - see HUGHES, ANNIE HARRIET
- VAUGHAN, HENRY (1621 - 1695), poet
- VAUGHAN, HERBERT MILLINGCHAMP (1870 - 1948), historian and author
- VAUGHAN, HILDA CAMPBELL (1892 - 1985), author
- VAUGHAN, Sir JOHN (1603 - 1674), judge
- VAUGHAN, JOHN (1663 - 1722) Derllys Court,, social and religious reformer
- VAUGHAN, JOHN (d. 1824), artist and violinist
- VAUGHAN, JOHN (1871 - 1956), general
- VAUGHAN, RICE (d. 1670), lawyer and author
- VAUGHAN, RICHARD (1550? - 1607), bishop
- VAUGHAN, ROBERT (1592? - 1667), antiquary, collector of the famous Hengwrt library
- VAUGHAN, Sir ROBERT WILLIAMES (d. 1859), baronet - see WYNN
- VAUGHAN, ROWLAND (c.1590 - 1667) Caer-gai,, poet, translator, and Royalist
- VAUGHAN, Sir THOMAS (d. 1483), soldier, court official, ambassador, chamberlain to the prince of Wales
- VAUGHAN, THOMAS (1621 - 1666), alchemist - see VAUGHAN, HENRY
- VAUGHAN, WILLIAM (1575 - 1641), author - see VAUGHAN
- VAUGHAN, WILLIAM (d. c. 1827) - see VAUGHAN, JOHN
- VAUGHAN, WILLIAM HUBERT (1894 - 1959), railway guard and chairman of the Welsh Land Settlement Society
- VAUGHAN-THOMAS, LEWIS JOHN WYNFORD (1908 - 1987), broadcaster, author and public figure
- VENABLES, Llysdinam Newbridge-on-Wye - see DILLWYN
- VENABLES-LLEWELYN, Llysdinam Newbridge-on-Wye - see DILLWYN
- VICARI, ANDREW (1932 - 2016), painter
- VILE, THOMAS HENRY (1882 - 1958), rugby player
- VINCENT family