Thanks to visit codestin.com
Credit goes to bmccancer.biomedcentral.com

Skip to main content
BMC is moving to Springer Nature Link. Visit this journal in its new home.

Articles

Page 1 of 383

  1. Multimodal care, including nutritional support, physical exercise, and pain management, is essential to address complex therapeutic challenges in advanced pancreatic cancer. There is an increasing prevalence w...

    Authors: Barlo Hillen, Gabrielle Oestreicher, Lisa Schwab, Kira Enders, Perikles Simon, Anneli Elme, Irit Ben-Aharon, Tal Goshenlago, Cindy Neuzillet, Francesco Sclafani, Eva Ester Molina Beltran, Michael Schuster, Hristina Doncheva, Christian Ruckes, Michael Karlecik, Katja Petrowski…
    Citation: BMC Cancer 2025 25:1610
    Content type: Study Protocol Published on:

  2. Prostate cancer (PCa) is one of the most prevalent malignancies in men, often progressing to castration-resistant forms and resisting conventional therapies. Curcumin, a polyphenol from Curcuma longa, has emerged...

    Authors: Mojtaba Esmaeli and Maryam Dehghanpour Dehabadi
    Citation: BMC Cancer 2025 25:1609
    Content type: Systematic Review Published on:

  3. Neoadjuvant immunotherapy combined with chemotherapy has achieved remarkable success in esophagus cancer. However, identifying the patients who may benefit from the neoadjuvant treatment remains a great challe...

    Authors: Liangliang Wu, Chaohu Pan, Wei Wang, Yiming Gao, Xiaoli Cui, Shengzhi Xie, Bo Yang, Jing Yuan, Man Chen, Jing Zhang, Haitao Luo, Tianyi Liu and Guoqing Zhang
    Citation: BMC Cancer 2025 25:1608
    Content type: Research Published on:

  4. In sub-Saharan Africa, the clinicopathological features, management strategies, and survival outcomes of nasopharyngeal carcinoma (NPC) remain underreported, posing challenges to improving patient care and tre...

    Authors: Kofi Adesi Kyei, Joseph Daniels, Tigist Tefera Degefu, Andrew Yaw Nyantakyi and Judith Naa Odey Tackie
    Citation: BMC Cancer 2025 25:1607
    Content type: Research Published on:

  5. Neuroblastoma tightly linked with genetic abnormality. The core genes responsible for RNA N1-methyladenosine (m1A) modification are critical in tumor development. Nevertheless, few reports revealed the function o...

    Authors: Susu Jiang, Siqi Dong, Yong Li, Lei Lin, Liping Chen, Wenli Zhang, Jinhong Zhu, Xinxin Zhang, Zhonghua Yang, Jiao Zhang, Jiwen Cheng, Li Li, Haixia Zhou, Suhong Li, Wenhan Yang, Jing He…
    Citation: BMC Cancer 2025 25:1606
    Content type: Research Published on:

  6. The influence of thyroid dysfunction on the clinical outcomes of head and neck cancer (HNC) patients remains an area of ongoing investigation, with previous studies yielding variable results. Treatments for HN...

    Authors: Sandeepa N. C, Tina S. Roberts, Johan Frank Opperman, Johan Grobbelaar and Muhammed Ajmal
    Citation: BMC Cancer 2025 25:1605
    Content type: Systematic Review Published on:

  7. Accurate preoperative T and TNM staging of clear cell renal cell carcinoma (ccRCC) is crucial for diagnosis and treatment, but these assessments often depend on subjective radiologist judgment, leading to inte...

    Authors: Wuchao Li, Yin Xi, Ming Lu, Junjie He, Jianguo Zhu, Haohan Li, Tongyin Yang, Xianchun Zeng, Xinfeng Liu, Rui Xu, Hui Huang, Heng Liu, Tijiang Zhang, Xiangde Min and Rongpin Wang
    Citation: BMC Cancer 2025 25:1604
    Content type: Research Published on:

  8. Cancer-associated fibroblasts (CAFs) play a critical role in the tumor microenvironment (TME) of breast cancer (BC), influencing immune evasion and treatment resistance. This study aims to explore the heteroge...

    Authors: Yingyi Li, Zhihui Zhang, Xin Liu, Yixin Cheng, Kang Li, Weihong Zheng and Zhenyu He
    Citation: BMC Cancer 2025 25:1603
    Content type: Research Published on:

  9. Hepatocellular carcinoma (HCC) prognosis remains poor in advanced stages. Stereotactic body radiation therapy (SBRT) combined with pharmacological agents (targeted therapies/immunotherapies) represents a promi...

    Authors: Shuaihao Hou, Suqin Hu, Qiong Wu, Haonan Sun, Zhongxuan Fang, Rong Sun, Liqun Wang and Bin Zhou
    Citation: BMC Cancer 2025 25:1602
    Content type: Systematic Review Published on:

  10. Cancer continues to pose a major global health burden, with rising incidence and mortality rates. The protracted timelines, and high costs associated with traditional drug development highlight the urgent need...

    Authors: Oluwatobi O. Olayode, Tolulope J. Oladosu, Ajibola I. Abioye, Emmanuel Olusola Oladeji and Blessing T. Ogunoye
    Citation: BMC Cancer 2025 25:1601
    Content type: Systematic Review Published on:

  11. Childhood cancers pose a significant public health challenge in sub-Saharan Africa (SSA) due to complex interlinked socioeconomic factors that contribute to delayed diagnoses, limited treatment options, and un...

    Authors: Abraham Tamirat Gizaw, Indryas Woldie, Abebayehu N. Yilma, Mulualem Tadesse, Assefa Legesse Sisay, Feyissa Mama Sebero, Henok Gulilat Azalework, Daniel Dana, Pradeep Sopory and Diriba Fufa Hordofa
    Citation: BMC Cancer 2025 25:1600
    Content type: Systematic Review Published on:

  12. Measurement of health-related quality of life (HRQoL) in patients with melanoma under immune checkpoint inhibitor therapy (ICI) under routine conditions and in survivorship is insufficient due to the absence o...

    Authors: Lea Pöschmann, Friedegund Meier, Martin Eichler, Frank Friedrich Gellrich, Jochen Schmitt and Olaf Schoffer
    Citation: BMC Cancer 2025 25:1599
    Content type: Research Published on:

  14. Accurate prediction of prognosis and risk stratification in patients with laryngeal cancer can inform appropriate treatment decision-making. This study aims to develop a multi-channel deep learning radiomics m...

    Authors: Haomiao Ma, Wenfeng Wei, Junhong Zhang, Li Liang, Lingyu Zhang, Wencan Wang, Qian Zhang, Qi Zhang, Yanhong Hao, Zhilin Li, Lingjie Wang and Hua Zhang
    Citation: BMC Cancer 2025 25:1597
    Content type: Research Published on:

  16. Fibronectin type III domain containing 1 (FNDC1) is a member of fibronectin type III domain protein family, which is known to play an important role in the metastasis of some cancers. However, it has not been ...

    Authors: Hongying Jiao, Jing Tian, Qiao Liu, Meng Jiang, Xia Niu, Wei Zhang and Li Gong
    Citation: BMC Cancer 2025 25:1595
    Content type: Research Published on:

  17. Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC), characterized by poor clinical behaviors and outcomes. TMOD1 was reported as a downstream target of NF-κB contributing to...

    Authors: Yijie Li, Xinyi Long, Yiting Xie, Xiaorong Zhong, Shiyu Cao, Fei Chen, Mengjia Shen, Lin Xiao, Lijuan Yin, Feng Ye and Ting Luo
    Citation: BMC Cancer 2025 25:1594
    Content type: Research Published on:

  18. Detecting programmed death-ligand 1 (PD-L1) expression helps identify patients likely to respond to PD-1/PD-L1 therapies. However, the high costs of PD-L1 assays, such as SP263 pharmDx, limit their widespread ...

    Authors: Fei Qu, Jingnan Wang, Qingqing Zhao, Hui Jiang, Xiaoyi Zhong, Qingqing Xu, Xinyu Yang, Liqiao Hu, Zhidong Zhang and Yan Zheng
    Citation: BMC Cancer 2025 25:1593
    Content type: Research Published on:

  19. Nipple-sparing mastectomy (NSM) with autologous tissue reconstruction offers excellent cosmetic outcomes but can be complicated by skin necrosis. This study aimed to investigate the risk factors for skin necro...

    Authors: Xuhui Guo, Xilong Gong, Yue Yang, Lina Wang, Lei Hou, Jiao Zhang, Yajie Zhao, Jia Wang, Hao Dai, Dechuang Jiao and Zhenzhen Liu
    Citation: BMC Cancer 2025 25:1592
    Content type: Research Published on:

  20. Taxanes are an effective class of chemotherapeutics, but they frequently cause chemotherapy-induced peripheral neuropathy (CIPN). CIPN complicates treatment, often leading to alterations or discontinuation. Th...

    Authors: Anukriti Sharma, Ken B. Johnson, Alper Sen, Bihua Bie, Emily E. Rhoades, Jacob Steenblik, Jennifer DeVecchio, Courtney Hershberger, Mei Wei, N. Lynn Henry, Carla Bou Dargham, G. Thomas Budd, Joseph Foss and Daniel M. Rotroff
    Citation: BMC Cancer 2025 25:1591
    Content type: Research Published on:

  21. Shared decision-making (SDM) improves outcomes in urinary reconstruction after radical cystectomy, but its implementation in China remains understudied. This qualitative study explores SDM barriers and facilit...

    Authors: Wang Li, Yiqin Shi, Liping Pu, Junyong Zhang, Mingyan He, Jianxia Chen and Xiaoqin Huang
    Citation: BMC Cancer 2025 25:1590
    Content type: Research Published on:

  22. Anaemia of inflammation represents a common form of anaemia. It is often clinically linked to pre-existing comorbidities but can also be a sign of cancer. This challenges the diagnostic evaluation, making it d...

    Authors: Astrid Boennelykke, Lene Sofie Granfeldt Østgård, Alina Zalounina Falborg and Peter Vedsted
    Citation: BMC Cancer 2025 25:1589
    Content type: Research Published on:

  23. Retinoblastoma (RB) is the most common primary intraocular malignancy in children. Its 5-year survival rate exceeds 90% if diagnosed early. However, delayed care-seeking allows the disease to advance to late s...

    Authors: Hong Ji, Junzhao Chen, Na Du, Shanshan Xiong, Yinghui Wu and Changjuan Zeng
    Citation: BMC Cancer 2025 25:1588
    Content type: Research Published on:

  24. In recent years, the incidence of papillary thyroid carcinoma (PTC) has been rapidly increasing, and thermal ablation techniques are gradually emerging as alternative therapies for PTC. The aim of this study w...

    Authors: Rongli Xie, Xiaoyin Tang, Tingyu Lin, Guohui Xiao, Yanna Zhao, Ying Liu, Min Ding, Lingling Tao, Weiwei Li, Yi Shen, Dongjie Shen, Shu-Rong Wang, Jianhua Gu, Ping Li and Jian Fei
    Citation: BMC Cancer 2025 25:1587
    Content type: Research Published on:

  25. Thyroid cancer encompasses distinct histological subtypes, each potentially associated with unique metabolic characteristics. However, the comprehensive metabolic reprogramming underlying these malignancies re...

    Authors: Raziyeh Abooshahab, Maryam Zarkesh and Mehdi Hedayati
    Citation: BMC Cancer 2025 25:1586
    Content type: Research Published on:

  26. This study aims to investigate the predictive value and optimal threshold of tumor-infiltrating lymphocytes (TILs) for neoadjuvant treatment response and long-term prognosis in breast cancer patients.

    Authors: Liangqiang Li, Peidong Yang, Chengye Hong, Debo Chen and Weibin Lian
    Citation: BMC Cancer 2025 25:1585
    Content type: Research Published on:

  27. The triglyceride-glucose (TyG) index, a surrogate marker for insulin resistance (IR), has recently been implicated in the development of multiple cancer types. However, its relationship with the pathological i...

    Authors: Meimei Pan, Yijie Yuan, Zhe Chen, Yanggang Dan, Bingchuan Hu, WenJie Song and Yongpeng Zhang
    Citation: BMC Cancer 2025 25:1584
    Content type: Research Published on:

  28. Therapy with radiotherapy in the head and neck, can be associated with gonadal damage in male survivors of cancer. To the authors’s knowledge the effect of treatments on testicular reproductive and endocrine f...

    Authors: Xiao Liu, Xuefeng Luo, Yang Xian, Lijuan Ying, Xiaofang Zhu, Yuanyuan Zeng, Siyu Long, Bo Liu and Fuping Li
    Citation: BMC Cancer 2025 25:1583
    Content type: Research Published on:

  29. When children are diagnosed with cancer, their parents often face psychological challenges such as post-traumatic stress disorder, anxiety, and depression, impacting both their quality of life and the child’s ...

    Authors: Xiaoyu Yang, Shanshan Jiang, Xiaotong Wang, Rong Wang, Pan Li, Na Cao and Xinying Yu
    Citation: BMC Cancer 2025 25:1582
    Content type: Systematic Review Published on:

  30. Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with limited effective treatment options, contributing to its high mortality of rate. Radiotherapy has shown effect in converting PDAC from a...

    Authors: Ziniu Tang, Fang Shi, Kunli Zhu, Rui Feng, Shumei Jiang, Minghuan Li, Lei Xu and Jinbo Yue
    Citation: BMC Cancer 2025 25:1581
    Content type: Study Protocol Published on:

  32. The integration of immunotherapy with chemotherapy (CT) has emerged as a major focus of clinical research in recent years for patients with advanced or recurrent endometrial cancer (EC). Recent phase 3 randomi...

    Authors: Rongxia Li, Xinmiao Zhang and Jinhai Shen
    Citation: BMC Cancer 2025 25:1579
    Content type: Research Published on:

  33. Standard treatment for stage III colon cancer is major surgical resection followed by adjuvant chemotherapy (ACT). Norwegian guidelines recommend initiation of ACT within 4–6 weeks after resection, but consens...

    Authors: Elin Marthinussen Gustavsen, Stig Norderval, Liv Marit Dørum, Eva Stensland, Ellinor Haukland, Yohannes Tesfay and Beate Hauglann
    Citation: BMC Cancer 2025 25:1578
    Content type: Research Published on:

  34. Digestive system cancers are a major global health burden, necessitating reliable and cost-effective prognostic biomarkers for clinical decision-making. The hemoglobin, albumin, lymphocyte, and platelet (HALP)...

    Authors: Caihua Qian, Jingting Liu, Chunyan Meng, Jun Cheng, Bo Wu and Jianhua Liao
    Citation: BMC Cancer 2025 25:1577
    Content type: Systematic Review Published on:

  35. This study aimed to explore the associations between body composition and markers related to disease severity in young females newly diagnosed with breast cancer.

    Authors: Jarson P. Costa-Pereira, Ingryd F. Macêdo, Giselle A. Barbosa, Glauber M. Leitão, Galtieri O. C. Medeiros, Ana L. Miranda, Gláucia M. C. Ferreira, Agnes D. L. Bezerra, Alcides S. Diniz, Ana Paula Trussardi Fayh and Sara M. M. L. Verde
    Citation: BMC Cancer 2025 25:1576
    Content type: Research Published on:

  36. Allostatic load (AL), reflecting chronic physiological stress across neuroendocrine, immune, and metabolic systems, may contribute to the onset and prognosis of multiple cancers via inflammation and stress-rel...

    Authors: Chenhao Xu, Da Huo, Yanxu Liu, Qiyu Zhu, Junjie Zhao, Jiayu Liang and Xianding Wang
    Citation: BMC Cancer 2025 25:1575
    Content type: Research Published on:

  39. Cachexia is a major challenge throughout cancer treatment. Unintentional weight loss, the principal diagnostic criterium of cancer cachexia, is usually assessed through self-reported body weight change, which ...

    Authors: N. D. Hildebrand, M. A. T. Sier, S. M. J. van Kuijk, L. S. M. Hoeijmakers, L. L. G. C. Ackermans, J. Ubachs, L. Stassen, N. F. M. Ruber, V. Schaghen-D’Antonio, E. P. Goedegebuure, L. Baade-Corpelijn, B. C. Bongers, J. Stoot, M. Sosef, S. Lambrechts, P. J. de Vos van Steenwijk…
    Citation: BMC Cancer 2025 25:1572
    Content type: Study Protocol Published on:

  40. Chemotherapy-induced neutropenia (CIN) and febrile neutropenia (FN) pose significant risks in patients with non-myeloid malignancies. This study aimed to evaluate the efficacy and safety of telpegfilgrastim in...

    Authors: Yanbing Zheng, Yan Zhang, Jia Li, Qin Liao and Hongming He
    Citation: BMC Cancer 2025 25:1571
    Content type: Research Published on:

  41. SRY-related high-mobility-group box gene 4 (SOX4) is overexpressed in various cancers and has been studied as a therapeutic target in multiple malignancies. Therefore, this study aims to investigate the role o...

    Authors: Hye-Bin Jang, Sun-Ae Kim, Eun Kyung Jung, Kyung-Hwa Lee, Joon Kyoo Lee, Young-Eun Joo, Yong Yeon Jeong, Sang Chul Lim and Tae Mi Yoon
    Citation: BMC Cancer 2025 25:1570
    Content type: Research Published on:

  42. The prognosis of pancreatic ductal adenocarcinoma remains dismal, largely because this disease is typically diagnosed at an advanced stage, making early detection a major challenge. Beyond the conventional bio...

    Authors: Jianchun Xiao, Xiaoyue Lu, Wenhao Luo, Yicheng Wang and Taiping Zhang
    Citation: BMC Cancer 2025 25:1569
    Content type: Research Published on:

  43. Brain metastases (BM) are a common complication in non-small cell lung cancer (NSCLC), associated with poor prognosis and limited survival without treatment. Previous studies have demonstrated a synergistic ef...

    Authors: Quan Zhang, Junzhu Xu, Shanshan Deng, Xin Li, Yan Wang, Ying Cai, Xuan Wang and Hu Ma
    Citation: BMC Cancer 2025 25:1568
    Content type: Research Published on:

  44. Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of taxane-based chemotherapy in breast cancer patients. Previous findings suggest that compression therapy may be a sa...

    Authors: Mai Okazaki, Aya Ueda, Akiko Iguchi-Manaka, Bryan J. Mathis, Kensuke Shimada, Takeshi Machino, Takeshi Yamada and Hiroko Bando
    Citation: BMC Cancer 2025 25:1567
    Content type: Research Published on:

  45. Although two pivotal phase III trials have evaluated the efficacy of adding immune-checkpoint inhibitors (ICIs) to concurrent chemoradiotherapy (CCRT) in locally advanced cervical cancer (LACC), discrepancies ...

    Authors: Ping Jiang, Shuhua Wei, Chunxiao Li, Ang Qu, Hongbo Chen, Hua Zhang, Hongyan Guo and Junjie Wang
    Citation: BMC Cancer 2025 25:1566
    Content type: Research Published on:

  46. Developing a machine learning model to predict post-transplant muscle loss in hepatocellular carcinoma patients.

    Authors: Jinyan Chen, Zhihang Hu, Huigang Li, Renyi Su, Zuyuan Lin, Jianyong Zhuo, Chiyu He, Ruijie Zhao, Wei Shen, Yajie You, Shuhan Jiang, Xuyong Wei, Shusen Zheng, Xiao Xu and Di Lu
    Citation: BMC Cancer 2025 25:1565
    Content type: Research Published on:

  47. The aim of this study was to develop a multimodal fusion model for accurate risk prediction and clinical decision support for ductal carcinoma in-situ (DCIS).

    Authors: Guoyan Yao, Yan Huang, Xiaojing Shang, Lei Guo, Jieping Feng, Zhongqiu Lai, Weikang Huang, Jianye Lu, Lijun Chen and Minan zheng
    Citation: BMC Cancer 2025 25:1564
    Content type: Research Published on:

  48. Capivasertib is recommended, plus fulvestrant, for hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer with PIK3CA/AKT1/PTEN alterations and is under development for...

    Authors: Jian Zhang, Xiaojun Liu, Yiqun Du, Yuxin Mu, Yanchun Meng, Yan Sun, Ling Zhang, Chris Chen, Marie Cullberg, Ethan Fan and Xichun Hu
    Citation: BMC Cancer 2025 25:1562
    Content type: Research Published on:

  50. Heat shock 90 kDa protein ATPase homolog 1 (AHSA1), a chaperone of heat shock protein 90 (Hsp90), is upregulated in various malignancies, where it promotes the invasion, migration, and proliferation of cancer ...

    Authors: Feihan Gu, Erli Wu, Xiaorong Yan, Wenkai Huang, Siyuan Chen, Weimin Bao, Wenhua Xu, Yuanyin Wang and Ran Chen
    Citation: BMC Cancer 2025 25:1560
    Content type: Research Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407