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Blood transfusion is a vital medical procedure used to treat patients with complications such as severe blood loss, blood disorders, cancers, and those undergoing surgery or experiencing obstetric emergencies....
The COVID-19 pandemic has highlighted the crucial role of testing in mitigating disease transmission. This study evaluates the effectiveness and cost-efficiency of various testing strategies, including daily s...
Drug-resistant pulmonary tuberculosis (DR-TB) remains a critical public health challenge, particularly affecting vulnerable populations such as the elderly, who exhibit higher morbidity and mortality rates. Th...
S gene mutations may lead to undetectable HBsAg, contributing to occult HBV infection (OBI). Nucleic acid testing (NAT) has been widely implemented to reduce transfusion-transmitted OBI. However, distinguishin...
Pseudomonas aeruginosa is a leading cause of burn wound infections, with pathogenicity driven by exotoxins and the Type III Secretion System (T3SS). Among its components, ExoA, ExoT, and the popB gene (T3SS trans...
The efficacy of LLINs is compromised by the emergence of pyrethroid resistance in malaria vectors. New insecticides that target other sites of action in the mosquito, including pyriproxyfen (PPF), are needed t...
We aimed to identify risk factors for breakthrough SARS-CoV-2 infection after at least one dose of any COVID-19 vaccine.
The malaria parasite, caused by Plasmodium falciparum, continues to pose serious public health threats in tropical and sub-tropical regions of the world, despite the availability of malaria vaccine. Since Octo...
Rapid tuberculosis (TB) diagnostics are essential for TB control. Factors influencing the uptake of these technologies in Africa are not well-documented for all technologies and are completely undocumented for...
Antimicrobial resistance (AMR) poses a critical global health challenge, exacerbated by the misuse of antibiotics. The COVID-19 pandemic has heightened this issue, particularly in low- and middle-income countr...
Glycemic variability (GV) and systolic blood pressure variability (SBPV) have been reported to be associated with all-cause mortality. However, it remains unclear whether the combination of these parameters fu...
The global rise in infections due to multidrug-resistant Gram-negative bacteria (MDRGNB) infections has disproportionately impacted immunocompromised (IC) hosts. Cefiderocol, a novel siderophore cephalosporin,...
Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB), but it fails to prevent the establishment and reactivation of latent TB. Overexpression of latency and re...
White piedra (WP) is a fungal infection that affects hair shafts, resulting in the formation of soft nodules that can be white, gray, or brown. While it was initially believed to be caused by Trichosporon beigeli...
Monitoring response to Multi-Drug-Resistant Tuberculosis (MDR-TB) treatment is burdensome to TB programmes and may benefit from alternative effective tools. We evaluated the concordance of alternative bacterio...
Listeria monocytogenes is one of the major bacteria responsible for meningitis. Controversy exists regarding the neuropathological effect of human pegivirus-1 (HPgV-1). Whether HPgV-1 interacts with L. monocytoge...
Multi-drug resistant pulmonary tuberculosis (MDR-TB), is a serious threat to world health. Serum levels of vitamin D, a ligand for the VDR that controls VDR mRNA expression, are still poorly understood in MDR-TB.
Hand, foot, and mouth disease (HFMD) is a significant public health challenge, particularly in Guangdong Province, China. Although spatio-temporal dynamics of HFMD have been studied, inter-regional transmissio...
Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant global health threat, particularly within the ESKAPE pathogens. Surveillance in Sub-Saharan Africa, including Gabon, remains limited despite ...
Effectiveness of currently deployed insecticide-based malaria vector control measures depends on continuous insecticide resistance monitoring and management. Urban malaria is becoming a serious health problem ...
With the rapid spread of COVID-19, many governments put various measures in place to contain the spread of the pandemic. These measures, such as travel restrictions, curfews, and public gatherings, may affect ...
Female HPV infection and depression have been linked to inflammation. However, the role that inflammation plays in the relationship between female HPV infection and depression remains unclear. This study inves...
Describe the prevalence of Mycoplasma pneumoniae (MP) in 2023, and investigate the influence of the relaxaion of COVID-19 pandemic control measures on MP prevalence. Analyze the positivity rates of MP in three di...
Hepatitis C Virus (HCV) causes liver diseases including chronic hepatitis, cirrhosis, and hepatocellular carcinoma. In low- and middle-income countries (LMICs), particularly sub-Saharan Africa (SSA), HCV diagn...
Blood urea nitrogen (BUN) levels had been reported to be Linked to the prognosis of critically ill patients. The purpose of this study is to investigate the association of the BUN trajectories with 28-day mort...
Constantly emerging SARS-CoV-2 genetic variants with potent immune escape kept the COVID-19 pandemic ongoing. Apart from vaccination, effective antiviral drug is necessary to achieve clinical improvement, espe...
In 2024, two cases of melioidosis were discovered in Chongqing, China. This was the first instance of non-traveler infection cases being found in this region. The strain characteristics and phylogenetic relati...
Extended spectrum beta-lactamases (ESBLs) and carbapenemase producing Acinetobacter baumannii and Pseudomonas aeruginosa are the top antibiotic-resistant priority list of pathogens representing the greatest threa...
The relationship between high-risk human papillomavirus (HR-HPV) infection outcomes and cervical lesion recurrence after conization is well documented. However, the temporal dynamics of human papillomavirus (H...
Actinobacillus ureae is a commensal found in the respiratory tract of humans. It is known to cause infections such as meningitis and septic arthritis in immunocompromised patients and also pneumonia especially in...
Acute gastroenteritis (AGE) is a prevalent gastrointestinal illness and a leading cause of morbidity and mortality among children younger than 5 years of age. Viral pathogens, group A rotavirus (RVA), noroviru...
While obesity paradox has been observed in various critical conditions, its role in sepsis remains unclear. This study aimed to investigate the relationship between body mass index (BMI) and 30-day in-hospital...
Tuberculosis (TB) remains a significant global public health challenge, with 10.8 million cases and 1.23 million deaths reported in 2023. Children comprised 11% of these cases and deaths globally. In Kenya, ap...
Ankylosing Spondylitis (AS) is a prevalent autoimmune disorder that necessitates the prolonged use of corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs), and disease-modifying antirheumatic drugs ...
Influenza viruses cause widespread respiratory illness. Due to limited surveillance, influenza dynamics in Namibia remain poorly understood. This study aimed to conduct molecular surveillance of influenza A an...
Incomplete tuberculosis (TB) treatment adherence may lead to unsuccessful treatment and relapse. Digital adherence technologies (DATs) may allow more person-centric approaches for supporting treatment adherenc...
Talaromycosis is an invasive fungal infection with high mortality in patients with advanced human immunodeficiency virus (HIV) disease in the tropical and subtropical regions of Asia. The lungs are the most co...
Gordonia bronchialis (G. bronchialis) is an emerging opportunistic pathogen that primarily affects immunocompromised individuals and is often associated with indwelling catheters.
Sepsis is a life-threatening disease and among the most common cause of death, which influence a series of following medical conditions. A comprehensive analysis of the cross-talks with temporary order of dise...
Tribal communities are disproportionately affected by hepatitis B virus (HBV) compared to non-tribal populations, posing a significant public health concern. This study aimed to assess the prevalence of and ri...
Venezuela’s recent economic and political instability has severely compromised its healthcare infrastructure, impacting the management of infectious diseases, including human immunodeficiency virus (HIV). This...
Brucellosis is a zoonosis caused by Brucella spp., with B. melitensis the most virulent in humans. Although typically presenting with non-specific systemic symptoms, rare but severe complications—disseminated int...
Visceral leishmaniasis (VL), also known as kala-azar, has posed significant challenges to elimination efforts due to increased reporting of new cases from high mountain and previously considered non-endemic ar...
Persistence and recrudescence of trachoma remain major challenges delaying progress towards elimination of the disease in many countries, including Ethiopia. Limited evidence exists regarding factors contribut...
The irrational use of broad-spectrum antibiotics in intensive care units (ICUs) has led to increasing bacterial
The COVID-19 pandemic has significantly impacted healthcare systems, leading to increased antibiotic misuse and multidrug-resistant (MDR) infections. This study assessed microorganisms and antibiotic-resistanc...
Infective endocarditis (IE) poses significant diagnostic challenges, particularly in blood culture-negative cases where fastidious bacteria evade detection. Metagenomic-based nanopore sequencing enables rapid ...
Tuberculosis (TB) is the leading cause of death from a single infectious agent, with approximately 1.2 million deaths reported in 2023. While TB primarily affects the lungs, it can also spread to other organs,...
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Citation Impact
Journal Impact Factor: 3.0 (2024)
5-year Journal Impact Factor: 3.1 (2024)
Source Normalized Impact per Paper (SNIP): 1.160 (2024)
SCImago Journal Rank (SJR): 1.035 (2024)
Speed
Submission to first editorial decision (median days): 10
Submission to acceptance (median days): 142
Usage 2024
Downloads: 9,189,426
Altmetric mentions: 13,503
The following summary describes the peer review process for this journal:
Identity transparency: Single anonymized
Reviewer interacts with: Editor
Review information published: Review reports. Reviewer Identities reviewer opt in. Author/reviewer communication