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Working from home
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Working from home
4 followers · 11 following

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Achievement: QuickdrawAchievement: Arctic Code Vault ContributorAchievement: Pull Shark

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AnaHowellsFerreira/README.md

Hi there 👋

My name is Ana, and I currently live near Portland, OR.

I have extensive experience in various areas of immunology research, including kidney/liver transplant and immuno-oncology. As a bench scientist, I have developed fundamental molecular skills related to biobanking, cryopreservation, logistics, clinical trials, and flow cytometry analysis.

In 2018, I began my training as a bioinformatician, driven by my curiosity about the R language and single-cell transcriptomics. Since then, I have worked with different versions of this technology, including multimodal 10x genomics analysis using scRNAseq, CITE-seq, HTO (hashtag), TCR-seq, some scATAC-seq, and currently, snRNAseq for non-immune cells. I have utilized various platforms for large-scale computing, such as HPCs, AWS, and Databricks. Most of the analysis tools my team uses are centered around Bioconductor R packages and the R language for creating reports and reproducible analyses (Shiny, FlexDashboard, Rmarkdown).

Since 2023, I have primarily worked in projects focused on testing downstream analysis packages for snRNAseq analysis of liver samples from patients diagnosed with Metabolic-associated Steato Hepatitis (MASH). We have evaluated tools for cell-cell communication, subtype annotation, velocity, GSEA, and pseudobulk differential expression analysis. Our projects are heavily centered around the biological question 🧬 and the commercialization of potential gene targets with Galnac (siRNA therapy).

My current project involves a large, collaborative effort between multiple centers in Europe to analyze snRNAseq data from a large cohort of patients with different stages of MASH disease.

I love what I do and I would love to get in touch. 🤝

As for personal projects and what I can share with you on github...

Personal projects

  • 💻 I’m currently working on updating my github profile
  • 📚 I am working on upskilling and expanding my knowledge beyond Bioinformatics. Stay tuned for new projects!
  • 📫 How to reach me: preferrably through linkedIn: https://www.linkedin.com/in/ana-howells-ferreira/

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  1. tcr_sequencing_tools tcr_sequencing_tools Public

    Forked from weshorton/tcr_sequencing_tools

    Misc tools for TCR sequencing pipelines

    R