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@TaschnerMandlGroup

TaschnerMandlGroup

Welcome to the Taschner-Mandl Lab at Children's Cancer Research Institute (CCRI) in Vienna

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We are a group of experimental and computational biologists at CCRI with the goal to tackle unresolved questions of neuroblastoma pathogenesis and develop new diagnostic and therapeutic approaches to facilitate precision medicine for children with malignant tumors. For more information visit our institutional homepage.

This organization hosts analysis and software repositories supporting our research.

  • NK-NB_study: Single cell RNA-seq analysis of bone marrow-derived NK cells in neuroblastoma metastasis samples
  • YAP-TAZ_study: Single cell transcriptomics & proteomic analysis of neuroblastoma primary tumor samples
  • neuroblastoma: Single-cell transcriptomics & epigenomics analysis for neuroblastoma samples
  • SpatialIMC: Spatial interaction analysis in IMC images
  • MapMetSC: Single-cell transcriptomics & proteomic analysis for data extracted from MapMetIP
  • MapMetIP: Image processing workflow for multi-modal (IF & IMC) high-plex images
  • DeepFLEX: Image processing and single-cell analysis pipeline for MELC images
  • ALT-FISH: Classification of ALT-FISH spots
  • AI4CAN: App for FISH image classification

Some repositories are currently in development and private, but will be published soon. Stay tuned.

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  1. NK-NB_study NK-NB_study Public

    Code for the publication Rados, Wernig-Zorc et al., 2025

    R 1

  2. MapMetSC MapMetSC Public

    MAPping METastases in Neuroblastoma - spatially and temporally

    R 1

  3. YAP-TAZ_study YAP-TAZ_study Public

    scRNA-seq analysis code for the publication Strohmenger et al., 2025

    Jupyter Notebook 1

  4. MapMetIP MapMetIP Public

    Image processing pipeline for multi-modal images

    Python

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