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melparker101/README.md

👋 Hi, I’m @melparker101.

👀 I’m interested in bioinformatics/computational medicine/systems biology.

🌱 I’m currently developing my Linux, Python and R skills.

💚 I'm a massive fan of Nextflow WMS.

🔥 My new interest is machine learning.

Projects have included:

  • Cancer systems biology
  • Cancer drug response prediction
  • Integration and annotation of scRNA-seq datasets
  • Variant calling from RNA seq data
  • Prioritising etiological cell-types (ovary and adipose cells)
  • Virus diagnostics (RNA respiratory viruses)
  • Bacterial antimicrobial-resistance outbreaks

Sequencing data handled:

  • Illumina scRNA/snRNA, bulk RNA, DNA
  • Nanopore DNA

Diseases/pathogens researched:

  • Neuroblastoma
  • SARS-CoV-2
  • Obesity and cardiometabolic diseases
  • Female infertility
  • Pan-cancer
  • Pan-virus
  • Escherichia coli and Klebsiella pneumoniae

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  1. Variant-Calling-from-RNA Variant-Calling-from-RNA Public

    Script for SNP calling from RNAseq data

    Shell