tsdf
calculates optimal Zhong's two-/three-stage Phase II designs, generates two-/three-stage Phase 1 dose finding decision table and allows user to run dose-finding simulations using customized decision table.
To install from CRAN
:
install.packages("tsdf")
To install latest version from github
:
install.packages("devtools")
devtools::install_github("wguo1990/tsdf")
[1] Bob Zhong, Single-arm phase IIA clinical trials with go/no-go decisions, 2012