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2026-01-14 : 20849 3D structures containing nucleic acids | RNAEQ v4.22all
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Jan 2026: New targets and procedures for validating valence geometry of NA structures. For more info visit NAKB's valence geometry standards page.

Welcome to NAKB

The Nucleic Acid Knowledgebase (NAKB), portal for 3D structural information about Nucleic Acids, is successor to the Nucleic Acid Database (NDB), as described in:

  • Lawson CL, Berman HM, Vallat B, Chen L, Zirbel C (2024) The Nucleic Acid Knowledgebase: a new portal for 3D structural information about nucleic acids. Nucleic Acids Research 52, D245. DOI
  • Berman HM, Lawson CL, Schneider B (2022) Developing Community Resources for Nucleic Acid Structures. Life 12, 540. DOI
  • November 2023 online lecture (YouTube) describing NAKB to the CASP RNA special interest group.

NAKB provides NA, Protein, and Ligand Annotations, Search, Report, Statistics, Atlas and Visualization for all nucleic-acid containing experimentally determined 3D structures held by NDB and by the Protein Data Bank (PDB), including all major methods: X-ray, Electron Microscopy, and NMR. For each structure, links are provided to external resources that annotate and analyze nucleic acid structures and their complexes.