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Real-world data on patients with locally advanced non-small cell lung cancer (LA-NSCLC) treated with chemoradiotherapy have been reported; however, prognostic factors in patients with negative or low programme...
This study evaluates the long-term anorectal function and rectal toxicity in rectal cancer patients who achieved a clinical complete response (cCR) to total neoadjuvant treatment (TNT) and were managed with a ...
Cone-beam computed tomography (CBCT)-based adaptive radiotherapy (ART) at the Ethos® linear accelerator (eLinac) allows for daily anatomical and dosimetric adjustments and relies on robust image quality. This stu...
Extramedullary hematopoiesis (EMH) is a compensatory response to chronic anemia, commonly observed in thalassemia. EMH can cause neurological complications such as spinal cord compression and paraparesis, as w...
This study examined the longitudinal changes in metabolic liver function and MR-morphological dilatation of intrahepatic bile ducts in patients with stereotactic body radiation therapy (SBRT) for liver metasta...
Bone metastases cause significant pain and functional limitation. Conventional external beam radiotherapy (EBRT) provides effective symptom relief, but local progression remains frequent. Stereotactic body rad...
Head and neck cancer (HNC), most of which are squamous cell carcinomas, is the seventh most common cancer worldwide. Radiotherapy is a standard treatment for HNC but may lead to late complications and severe c...
Advancements in cone beam computed tomography (CBCT)-guided radiotherapy (RT) platforms have created new frontiers in adaptive radiotherapy (ART). This report describes the novel application of single-fraction...
To optimize an animal model of acute radiation-induced esophagitis (RIE) in C57BL/6 mice and characterize the histopathological features of RIE at different stages.
We sought to evaluate the efficacy and toxicity of stereotactic body radiotherapy (SBRT) for hepatocellular carcinoma with tumor thrombus in right atrium (RATT).
Pelvic nodal irradiation is often used for high-risk prostate adenocarcinoma. A commonly used alternative to low dose rate (LDR) brachytherapy, a 3-fraction SBRT boost with fiducial tracking may allow for bett...
High-dose prescribed radiotherapy has been attempted to improve local control and restore portal vein in patients with hepatocellular carcinoma (HCC) complicated with portal vein tumor thrombus (PVTT). The aim...
To investigate the impact of two neoadjuvant radiotherapy regimens on survival outcomes and adverse reactions in patients with locally advanced low and mid rectal cancer.
Precise delineation of gross tumor volume (GTV) is fundamental for effective radiation therapy in low-grade skull base meningiomas. Magnetic resonance imaging (MRI) serves as the primary imaging tool but may n...
The original article was published in Radiation Oncology 2025 20:55
Radiation oncology is increasingly turning to Artificial Intelligence (AI) - and in particular Chat Generative pre-trained transformer (ChatGPT) - for decision support, patient education, and workflow efficien...
Stereotactic Body Radiotherapy (SBRT) has been proven to be a safe and effective alternative to surgery in patients with metastatic primary sarcoma. However, data describing tumor response in relation to the g...
Recent advances in radiation biology and preclinical research have identified that high doses of radiation at ultra-high dose rate can lead to sparing of normal tissue, while maintaining tumor control. This ha...
In this study we examined the correlation between standardized uptake value (SUV) of [18F]fluorodeoxyglucose (FDG) and apparent diffusion coefficient (ADC) within the gross tumor volume (GTV) of patients with hea...
Ventricular tachycardia (VT) is a potentially life-threatening arrhythmia, that can lead to sudden cardiac death. While conventional treatments include antiarrhythmic drugs, catheter ablation, and ICD implanta...
To evaluate the precision of automated segmentation facilitated by deep learning (DL) and dose calculation in adaptive radiotherapy (ART) for nasopharyngeal cancer (NPC), leveraging synthetic CT (sCT) images d...
Radiotherapy (RT) is a standard curative treatment for prostate cancer (PCa) and there is growing evidence of the high efficacy of moderate and ultra-hypofractionated RT. Reducing treatment duration to one wee...
Focal tumor irradiation, a cornerstone of cancer therapy, has been increasingly recognized for its capacity to provoke systemic immunogenic responses that extend beyond localized tumor control. Recent advances...
We present a case of extensive and bulky pediatric metastatic melanoma originating in the head and neck which markedly responded to combination therapy with anti-programmed cell death (PD-1) inhibition and con...
Knowledge-Based Planning (KBP) pipelines, which integrate machine learning-based models to predict dose distribution, have gained popularity in clinical radiation therapy. However, for patients with specific r...
This study aimed to evaluate the clinical feasibility and performance of CT-based auto-segmentation models integrated into an All-in-One radiotherapy workflow for rectal cancer.
Local control prediction for patients with pulmonary oligometastases underwent stereotactic body radiotherapy (SBRT) is crucial for optimizing therapeutic strategies. This study aims to develop and validate a ...
Bladder cancer radiotherapy presents unique challenges due to the dynamic anatomy of the bladder and the surrounding organs. Conventional image-guided radiotherapy (IGRT) relies on fixed treatment margins and ...
Radiomics models frequently face challenges related to reproducibility and robustness. To address these issues, we propose a multimodal, multi-model fusion framework utilizing stacking ensemble learning for pr...
In individuals presenting with locally advanced rectal cancer, the therapeutic strategy of neoadjuvant concurrent chemoradiotherapy (CCRT) aims to enhance tumor downstaging; however, only a subset of patients ...
To determine the impact of tumor characteristics such as tumor volume, circumference and location in the rectum on intrafraction motion during dose-escalated MRI-guided radiotherapy of rectal cancer and to exp...
Gliomas with isocitrate dehydrogenase (IDH) mutation affect young adults with a long-life expectancy. While radiotherapy is effective, studies have shown its detrimental effects on cognition and quality of life. ...
To evaluate long-term outcomes, treatment costs, and quality of life associated with curative treatment of newly diagnosed stage I non-small cell lung cancer (NSCLC), by comparing surgery to stereotactic body ...
Proton therapy is commonly used for treating hepatocellular carcinoma (HCC); however, its feasibility can be challenging to assess in large tumors or those adjacent to critical organs at risk (OARs), which are...
Neoadjuvant (preoperative) radiochemotherapy (nRCT) is a standard of care in locally advanced rectal cancer (LARC). Several studies have shown that the decline in 18FDG uptake after 2 weeks of nRCT compared with ...
Patients with brain metastases face a poor prognosis when deemed not to be suitable for onco-surgical intervention. This feasibility study analyses the outcome of adaptive radiosurgery applied in customised se...
Proprietary bi-nuclide plaques combine the radiation properties of beta and gamma brachytherapy and can irradiate a larger target volume compared to ruthenium-plaques. While reducing the dose to structures out...
This study aimed to develop and validate a multi-temporal magnetic resonance imaging (MRI)-based delta-radiomics model to accurately predict severe acute radiation enteritis risk in patients undergoing total n...
This study aimed to quantify dynamic changes in the Apparent Diffusion Coefficient (ADC) values of the parotid glands during radiotherapy and explore their correlation with early-stage gland dysfunction.
Recent advances in Radiotherapy have led to the development of online adaptive RT (oART), a procedure addressing inter-fraction anatomical variations. Integrating artificial intelligence (AI) into the oART pro...
Anatomical variations that occur during radiation therapy in head and neck cancer (HNC) patients can lead to significant dosimetric changes. The purpose of this study is to evaluate dosimetric and volume chang...
Comorbid mental health symptoms impact 30–40% of cancer patients, significantly compromising treatment adherence and increasing mortality rates. Among patients undergoing radiation therapy, which is delivered ...
Lung cancer primarily affects elderly individuals and is the leading cause of cancer-related death in people aged 80 years and older. In addition, the incidence of multiple primary lung cancer (MPLC) is increa...
External beam radiotherapy (EBRT) is an essential component of standard treatment for locally advanced cervical cancer. Moderately hypofractionated radiotherapy (MHRT) offers the potential to reduce treatment ...
To assess the effect of treatment time and waiting time on clinical outcome for patients with esophageal squamous cell carcinoma (ESCC) treated with definitive concurrent chemoradiotherapy (CCRT).
Stereotactic radiotherapy with Gamma Master System® delivered for portal vein tumor thrombosis (PVTT) located in the main portal vein is previously exploited. The study aimed to evaluate the efficacy and safety o...
Liver cancer is a major contributor to cancer-related mortality. Selective internal radiation therapy (SIRT) for liver cancer has garnered increasing attention. This study aims to comprehensively describe the ...
The PEGASUS trial was the first study to evaluate and demonstrate the benefits of 68Ga-perfusion PET/CT in the lung stereotactic body radiotherapy (SBRT) planning process in preserving functional lung volumes whi...
This study aimed to assess the clinical outcomes and prognostic factors of patients with synchronous head and neck squamous cell carcinoma (HNSCC) and esophageal squamous cell carcinoma (ESCC) who underwent si...
Stereotactic radiotherapy (SRT) for kidney cancer, particularly when tumours are situated near critical organs-at-risk (OARs), presents significant challenges in achieving optimal dose delivery. MR-guided onli...
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5-year Journal Impact Factor: 3.8 (2024)
Source Normalized Impact per Paper (SNIP): 1.203 (2024)
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