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Biological and medical applications of the Symmetrical Convergence (SymC) framework. Exploring critical damping in cellular, neurological, and immune systems for stability and adaptive control.

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Symmetrical Convergence (SymC) — Bio Repository

Overview

This repository contains the biological, neurological, and medical branch of the Symmetrical Convergence (SymC) research program.

SymC is a unifying physical framework built around a single governing principle: adaptive systems achieve maximal stability and information efficiency at the critical damping boundary. Across domains, failure, disease, and inefficiency arise when systems drift into underdamped (chaotic) or overdamped (rigid) regimes.

Within biology and medicine, this manifests as:

  • Disease as control instability, not isolated pathology
  • Comorbidity as phase-shifted expressions of a shared stability substrate
  • Treatment as boundary restoration, not symptom suppression

This repository consolidates the SymC work that applies these principles to viral dynamics, oncology, neurodegeneration, pain, addiction, psychiatric instability, and adaptive therapeutic control.


Scope of Work

Across the SymC bio program, we have:

  • Reframed biological regulation as a dynamical control problem
  • Unified chronic disease, neurodegeneration, and mental illness under shared stability mechanics
  • Introduced stability ratios and phase metrics as actionable diagnostic tools
  • Demonstrated how adaptive intervention outperforms static treatment strategies
  • Linked molecular, cellular, neural, and behavioral dynamics within a single substrate model

Canonical SymC Biology & Medicine Papers

I. Core Biological Control Frameworks

  1. SymC Viral Control: A Stability-Ratio Method for Adaptive Therapeutic Dynamics DOI: https://doi.org/10.5281/zenodo.17651256

  2. Optimal Control Theory in Oncology (SymC Oncology Framework) DOI: https://doi.org/10.5281/zenodo.17507544


II. Neurodegeneration and Progressive Instability

  1. Prodromal Critical Cascade in Parkinson's Disease: A SymC Framework for Early Detection, Phenotype Dynamics, and Precision Intervention DOI: https://doi.org/10.5281/zenodo.17645851

  2. SymC Neurostability Principle: The Governing Physics of Alzheimer's and Dementia Instability Architectures DOI: https://doi.org/10.5281/zenodo.17766309


III. Pain, Addiction, and Neural Control Failure

  1. Neuroelastic Resonance Instability: A SymC Critical-Damping Principle of Addiction and Neural Control Failure DOI: https://doi.org/10.5281/zenodo.17782917

  2. The Nociceptive Stability Principle: SymC Substrate Architecture for Adaptive Pain Control DOI: https://doi.org/10.5281/zenodo.17924428


IV. Psychiatric Stability and Comorbidity

  1. SymC Boundary Dissolves Comorbidity Paradox: Redefining the Phase-Shifting Mechanical Lineage of Mental Illness as Neuro Stability Disorder DOI: https://doi.org/10.5281/zenodo.17937287

Related Cross-Domain SymC Works (Contextual)

The following papers inform the biological models but are housed in other SymC repositories:


How to Use This Repository

This repository is intended for:

  • Researchers exploring systems biology and disease dynamics
  • Clinicians interested in adaptive, phase-aware intervention models
  • Control theorists applying feedback principles to living systems
  • AI and computational biology teams developing adaptive treatment algorithms

Each paper is designed to be read independently, but together they form a single, closed theoretical system.


Citation and Usage

All works are archived on Zenodo and may be cited individually via their DOIs.

If referencing the SymC bio framework as a whole, please cite the relevant primary paper(s) alongside the foundational SymC boundary postulate.


Program Status

This repository represents a mature, internally consistent branch of the SymC research program. Future updates may include:

  • Clinical validation datasets
  • Computational simulation modules
  • Adaptive control implementations

Core theory is considered stable.

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