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Using the Boltz-2 Affinity Module with a Known Structure

Status: Open.

#702 In jwohlwend/boltz;

· MartinFuentetaja opened on Sep 8, 2026

Question on side chain predictions with given template

Status: Open.

#701 In jwohlwend/boltz;

· BJWiley233 opened on Sep 4, 2026

improve the robustness of the ligand 3D conformation generation

Status: Open.

#700 In jwohlwend/boltz;

· AIMedDrug opened on Aug 1, 2026

Feature request: expose PAE (and confidence JSON) in the hosted API output

Status: Open.

#697 In jwohlwend/boltz;

· Ayushmania2002 opened on Jul 17, 2026

pdb vs mmcif output_format

Status: Open.

#696 In jwohlwend/boltz;

· marissadolorfino2024 opened on Jul 9, 2026

Request for correction: Boltz manifest draft in OpenSciFlow

Status: Open.

#695 In jwohlwend/boltz;

· kkkniengLiu opened on Jul 6, 2026

ConnectTimeoutError to api.colabfold.com when using Boltz --use_msa_server

Status: Open.

#694 In jwohlwend/boltz;

· Kj-23 opened on Jun 30, 2026

ConnectTimeoutErrorwhen fetching fromapi.colabfold.com during high-throughput screening

Status: Open.

#693 In jwohlwend/boltz;

· ChenSyyJR opened on Jun 29, 2026

training code for boltz-2

Status: Open.

#687 In jwohlwend/boltz;

· YueZhou-oh opened on May 28, 2026

Training preprocessing: rcsb.py does not correctly populate cluster_id or msa_id for custom mmCIF datasets

Status: Open.

#686 In jwohlwend/boltz;

· ReaganGen opened on May 27, 2026

[Bug] steering_args['fk_steering'] raises TypeError when steering_args is None (diffusionv2.py:323)

Status: Open.

#680 In jwohlwend/boltz;

· Chabname opened on May 13, 2026

[Bug] pairformer_args.v2 missing from checkpoint hyper_parameters → AttentionPairBias.forward() unexpected kwarg 'k_in'

Status: Open.

#679 In jwohlwend/boltz;

· Chabname opened on May 13, 2026