GeneRHi-C (pronounced "generic")

3D GENomE Reconstruction from Hi-C data

A pre-print describing this work has been published on BioRxiv (https://doi.org/10.1101/392407)

The IP model has been published as a confrence paper as a part of CSBio '19: Proceedings of the Tenth International Conference on Computational Systems-Biology and Bioinformatics (https://dl.acm.org/doi/10.1145/3365953.3365962)

This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.

The following is a brief description of the contents of each folder:

- data: contains the original s. pombe data and adjacency matricies that were used for step 1
- step 1: contains the three mathematical models and their results
- step 2: contains the script for generating the graph-representation from the reduced set of interactions
  identified in step 1 and the results
- step 3: contains the JYZ3D script for generating xyz coordinates and the results