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NWAS-RP

NWAS-RP is a Network-based GWAS re-prioritization software toolkit for mining high-level imaging genetic associations using tissue-specific functional networks and network GWAS reprioritization strategy.

Example data is available at https://upenn.app.box.com/s/epj9r0rm1avt6nkm4frtuv1xmq0b8ta3.

References

Yao X, Yan J, Liu K, Kim S, Nho K, Risacher SL, Greene CS, Moore JH, Saykin AJ, Shen L, for the ADNI. (2017) Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules. Bioinformatics, 2017 May 29. doi: 10.1093/bioinformatics/btx344.

Yao X, Yan J, Risacher S, Moore J, Saykin A, Shen L. (2017) Network-based genome wide study of hippocampal imaging phenotype in Alzheimer’s disease to identify functional interaction modules. ICASSP'17: The 42nd IEEE International Conference on Acoustics, Speech and Signal Processing, 10.1109/ICASSP.2017.7953342, New Orleans, March 5-9, 2017.

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Network-based GWAS re-prioritization and module identification

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