In [1]: np.__version__
Out[1]: '1.8.0'

In [2]: np.arange(10)
Out[2]: array([0, 1, 2, 3, 4, 5, 6, 7, 8, 9])

In [3]: _2.flags.writeable = False

In [4]: _2[[1,2,3]] = 100
---------------------------------------------------------------------------
ValueError                                Traceback (most recent call last)
<ipython-input-4-6b16d30888f3> in <module>()
----> 1 _2[[1,2,3]] = 100

ValueError: assignment destination is read-only

In [5]: _2.flat[[1,2,3]] = 100
---------------------------------------------------------------------------
ValueError                                Traceback (most recent call last)
<ipython-input-5-ad5ff20cf609> in <module>()
----> 1 _2.flat[[1,2,3]] = 100

ValueError: underlying array is read-only

In [6]: _2.put([1,2,3], 100)

In [7]: _2
Out[7]: array([  0, 100, 100, 100,   4,   5,   6,   7,   8,   9])