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Top 23 Python Deep Learning Projects
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Link (Github): https://github.com/AUTOMATIC1111/stable-diffusion-webui
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Stream
Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.
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transformers
๐ค Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.
python3.12 -m venv new_venv_312 source new_venv_312/bin/activate pip install --upgrade pip pip install https://github.com/huggingface/transformers/archive/main.zip torchaudio peft soundfile torchcodec ### and also pip install librosa
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Project mention: The bug that taught me more about PyTorch than years of using it | news.ycombinator.com | 2025-10-26
He's not a core maintainer and hasn't been for years - pytorch's contributors are completely public
https://github.com/pytorch/pytorch/graphs/contributors
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ragflow
RAGFlow is a leading open-source Retrieval-Augmented Generation (RAG) engine that fuses cutting-edge RAG with Agent capabilities to create a superior context layer for LLMs
Project mention: The AI-Native GraphDB + GraphRAG + Graph Memory Landscape & Market Catalog | dev.to | 2025-10-26 -
nn
๐งโ๐ซ 60+ Implementations/tutorials of deep learning papers with side-by-side notes ๐; including transformers (original, xl, switch, feedback, vit, ...), optimizers (adam, adabelief, sophia, ...), gans(cyclegan, stylegan2, ...), ๐ฎ reinforcement learning (ppo, dqn), capsnet, distillation, ... ๐ง
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Keras 3 multi-backend
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InfluxDB
InfluxDB โ Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
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Project mention: Labellerr YOLOv8: Cars and Number Plate Detection โ Practical, Step-by-Step | dev.to | 2025-11-05
YOLOv8(by Ultralytics) is one of the most widely used state-of-the-art object detection models. It is known for delivering high accuracy, while still being fast enough for real-time detection.
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Project mention: Show HN: Using YOLO to Detect Office Chairs in 40M Hotel Photos | news.ycombinator.com | 2025-01-25
They did it on their own computer. https://github.com/ultralytics/ultralytics
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Project mention: 2025 Voice AI Guide: How to Make Your Own Real-Time Voice Agent (Part-1) | dev.to | 2025-09-20
XTTS-v2 โ Zero-shot voice cloning, 17 languages, streaming support
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Project mention: How to Build a RAG Solution with Llama Index, ChromaDB, and Ollama | dev.to | 2025-11-04
With a few lines of Python, you can build a basic retrieval-augmented generation (RAG) solution, but it doesnโt stop here. You can extend this project to search for multiple web pages, load large documents, add a simple web UI using either Streamlit or Anvil, or even experiment with different models in Ollama.
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DeepSpeed
DeepSpeed is a deep learning optimization library that makes distributed training and inference easy, efficient, and effective.
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gradio
Build and share delightful machine learning apps, all in Python. ๐ Star to support our work!
Project mention: The Ultimate Guide to Building Stunning AI Apps For Beginners - Gradio | dev.to | 2025-11-14Why Gradio is the New Superpower for Every AI Learner in 2025
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Ray
Ray is an AI compute engine. Ray consists of a core distributed runtime and a set of AI Libraries for accelerating ML workloads.
Not currently, but it is being worked on https://github.com/ray-project/ray/issues/53976.
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Deep-Learning-Papers-Reading-Roadmap
Deep Learning papers reading roadmap for anyone who are eager to learn this amazing tech!
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MockingBird
๐AIๆๅฃฐ: 5็งๅ ๅ ้ๆจ็ๅฃฐ้ณๅนถ็ๆไปปๆ่ฏญ้ณๅ ๅฎน Clone a voice in 5 seconds to generate arbitrary speech in real-time
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Project mention: Show HN: Plug-and-play Python utils for any computer-vision pipeline | news.ycombinator.com | 2025-07-21
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qlib
Qlib is an AI-oriented Quant investment platform that aims to use AI tech to empower Quant Research, from exploring ideas to implementing productions. Qlib supports diverse ML modeling paradigms, including supervised learning, market dynamics modeling, and RL, and is now equipped with https://github.com/microsoft/RD-Agent to automate R&D process.
After researching different AI models in Qlib (a quantitative finance platform), here's what I learned:
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Project mention: Strengthening Open-Source Integrity: My First Contribution to spaCy | dev.to | 2025-10-28
๐ Pull Request: #13877 โ Remove spaCy Quickstart from Universe/Courses due to spam redirect
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SaaSHub
SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives
NOTE:
The open source projects on this list are ordered by number of github stars.
The number of mentions indicates repo mentiontions in the last 12 Months or
since we started tracking (Dec 2020).
Python Deep Learning discussion
Python Deep Learning related posts
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Comic Translate: Unleash the Power of GPT-4 for Flawless Global Comic Translation
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Show HN: Open-Source LaTeX OCR, Alternative to Mathpix/SimpleTex
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Notes on the margins
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Python library for quantum computing, quantum ML, and quantum chemistry
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LazyLLM, Easiest and laziest way for building multi-agent LLMs applications
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LitServe: Build custom AI inference engines
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maze VS pi-optimal - a user suggested alternative
2 projects | 30 Oct 2025 -
A note from our sponsor - Stream
getstream.io | 16 Nov 2025
Index
What are some of the best open-source Deep Learning projects in Python? This list will help you:
| # | Project | Stars |
|---|---|---|
| 1 | stable-diffusion-webui | 158,141 |
| 2 | transformers | 152,508 |
| 3 | Pytorch | 94,956 |
| 4 | ragflow | 67,441 |
| 5 | nn | 64,273 |
| 6 | Keras | 63,551 |
| 7 | Real-Time-Voice-Cloning | 58,832 |
| 8 | yolov5 | 56,018 |
| 9 | faceswap | 54,691 |
| 10 | ultralytics | 48,563 |
| 11 | TTS | 43,441 |
| 12 | streamlit | 42,140 |
| 13 | ColossalAI | 41,234 |
| 14 | DeepSpeed | 40,641 |
| 15 | gradio | 40,497 |
| 16 | Ray | 39,825 |
| 17 | Deep-Learning-Papers-Reading-Roadmap | 39,241 |
| 18 | GFPGAN | 37,167 |
| 19 | MockingBird | 36,745 |
| 20 | supervision | 35,881 |
| 21 | qlib | 33,724 |
| 22 | spaCy | 32,785 |
| 23 | pytorch-tutorial | 31,911 |
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