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Top 23 Python Desktop Projects
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flet
Flet enables developers to easily build realtime web, mobile and desktop apps in Python. No frontend experience required.
Project mention: FletX: Bring Reactive Power to Your Python UI with GetX-Like Simplicity | dev.to | 2025-06-15Meet FletX — a lightweight framework built on top of Flet that brings reactivity and clean architecture to Python GUI apps.
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InfluxDB
InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
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pythonguis-examples
Demo desktop apps built with Python & Qt. With examples for PyQt6, PySide6, PyQt5 & PySide2
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Project mention: Windows-MCP: The MCP for AI to Interact with Windows Apps | news.ycombinator.com | 2025-06-25
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A guy in Brazil who coded up:
https://nodezator.com/
because it was the first Python node editor which "just worked" out of the box when I tried to run it.
Based on a game dev system which was called Indie Python, the main site is now at:
https://indiesmiths.com/
I kick in to Wikipedia via Microsoft Rewards points whenever they are matching points, or if I have a surplus of Amazon gift card money 'cause there haven't been any Kindle book sales I bought into for a while.
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Stream
Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.
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Project mention: A Beautiful Python GUI Framework with Theming, State Binding and Live Hot Reload | news.ycombinator.com | 2025-06-27
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nwg-wrapper
Wrapper to display a script output or a text file content on the desktop in sway or other wlroots-based compositors
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kobold_assistant
Like ChatGPT's voice conversations with an AI, but entirely offline/private/trade-secret-friendly, using local AI models such as LLama 2 and Whisper
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Shamelessly promoting here, I created an architecture that allows an AI agent to have those so called "tools" available locally (under the user control), and works with any kind of LLMs, and with any kind of server (in theory). I've been showing demos about it for months now. Works as a middle-ware, in stream, between the LLM server and the chat client, and works very well. The repo is outdated, simply because no one is expressing interest in looking into the code. But here is the repo: https://github.com/khromalabs/Ainara. There's a link to a video in there.
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Encrypted-Tkinter-Password-Manager
A small python-based password manger/generator utilizing Fernet Symmetric Encryption, SQLite, and Tkinter.
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SaaSHub
SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives
NOTE:
The open source projects on this list are ordered by number of github stars.
The number of mentions indicates repo mentiontions in the last 12 Months or
since we started tracking (Dec 2020).
Python Desktop discussion
Python Desktop related posts
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A Beautiful Python GUI Framework with Theming, State Binding and Live Hot Reload
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Nodezator: Make apps by connecting Python functions visually
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Nodezator is a generalist Python node editor
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A generalist Python node editor
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FLaNK Weekly 18 Dec 2023
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Nodezator v1.4 released! (Python node editor in the public domain)
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Is there any official app for Windows? How can I download my songs on my desktop? I cannot see that option, like when on youtube videos
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A note from our sponsor - Stream
getstream.io | 16 Nov 2025
Index
What are some of the best open-source Desktop projects in Python? This list will help you:
| # | Project | Stars |
|---|---|---|
| 1 | flet | 14,740 |
| 2 | fsociety | 11,633 |
| 3 | pythonguis-examples | 4,482 |
| 4 | Windows-MCP | 3,409 |
| 5 | nodezator | 2,681 |
| 6 | pyprland | 624 |
| 7 | gtg | 592 |
| 8 | rednotebook | 539 |
| 9 | trufont | 498 |
| 10 | komorebi | 301 |
| 11 | winup | 193 |
| 12 | nwg-wrapper | 177 |
| 13 | kobold_assistant | 160 |
| 14 | termux-desktop-lxqt | 156 |
| 15 | gotify-tray | 105 |
| 16 | bigbashview | 64 |
| 17 | gnome-gmail | 53 |
| 18 | ainara | 32 |
| 19 | SpotifyGlobal | 25 |
| 20 | input-device-indicator | 25 |
| 21 | ChatGPT-Desktop-Webview | 20 |
| 22 | Encrypted-Tkinter-Password-Manager | 9 |
| 23 | Python-CameraApp | 8 |
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