Top 23 Python SDK Projects

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1. qiskit

   1 28 6,666 9.8 Python

   Qiskit is an open-source SDK for working with quantum computers at the level of extended quantum circuits, operators, and primitives.

   

   Project mention: Introducing SuperQuantX: Foundational Research for Quantum and Agentic AI | dev.to | 2025-09-12

   SuperQuantX provides one consistent API that connects to a wide set of quantum frameworks such as PennyLane, Qiskit, Cirq, Amazon Braket, TKET, and D Wave Ocean. With that single interface you can run the same research code across different backends while keeping experiments reproducible and portable. This reduces friction and accelerates iteration for teams and for individual researchers.

2. Stream

   getstream.io featured

   Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.

   

3. Cirq

   2 5 4,766 9.8 Python

   Python framework for creating, editing, and invoking Noisy Intermediate-Scale Quantum (NISQ) circuits.

   

   Project mention: Introducing SuperQuantX: Foundational Research for Quantum and Agentic AI | dev.to | 2025-09-12

   SuperQuantX provides one consistent API that connects to a wide set of quantum frameworks such as PennyLane, Qiskit, Cirq, Amazon Braket, TKET, and D Wave Ocean. With that single interface you can run the same research code across different backends while keeping experiments reproducible and portable. This reduces friction and accelerates iteration for teams and for individual researchers.

4. borb

   3 66 3,541 8.9 Python

   borb is a library for reading, creating and manipulating PDF files in python.

   

5. mmdeploy

   4 4 3,044 4.7 Python

   OpenMMLab Model Deployment Framework

   

6. opentelemetry-python

   5 7 2,215 9.2 Python

   OpenTelemetry Python API and SDK

   

   Project mention: LLM Observability in the Wild – Why OpenTelemetry Should Be the Standard | news.ycombinator.com | 2025-09-27

   Yes, it is happening because OpenInference assumes these span kind values https://github.com/Arize-ai/openinference/blob/b827f3dd659fc...

   Anything which doesn't fall in other span kinds is classified as `unknown`

   For reference, these are span kinds which opentelemetry emits - https://github.com/open-telemetry/opentelemetry-python/blob/...

7. sentry-python

   6 4 2,096 9.8 Python

   The official Python SDK for Sentry.io

   

8. quantum

   7 8 2,036 8.0 Python

   An open-source Python framework for hybrid quantum-classical machine learning.

   

   Project mention: Quantum AI : The Next Frontier in Computing | dev.to | 2025-05-20

   TensorFlow Quantum Documentation

9. InfluxDB

   www.influxdata.com featured

   InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.

   

10. solana-py

    8 5 1,418 7.7 Python

    Solana Python SDK

    

11. minio-py

    9 9 1,006 7.2 Python

    MinIO Client SDK for Python

    

12. dropbox-sdk-python

    10 5 967 3.4 Python

    The Official Dropbox API V2 SDK for Python

    

    Project mention: 50+ APIs (All Free!) For Savvy Marketers & Content Developers🔥 | dev.to | 2025-06-13

    42. Dropbox API

13. hera

    11 2 818 9.0 Python

    Hera makes Python code easy to orchestrate on Argo Workflows through native Python integrations. It lets you construct and submit your Workflows entirely in Python. ⭐️ Remember to star!

    

14. huobi_Python

    12 1 694 3.3 Python

    Python SDK for Huobi Spot API

    

15. pocketbase

    13 2 506 6.4 Python

    PocketBase client SDK for python (by vaphes)

    

16. GraphRAG-SDK

    14 13 493 9.0 Python

    Build fast and accurate GenAI apps with GraphRAG SDK at scale.

    

    Project mention: The AI-Native GraphDB + GraphRAG + Graph Memory Landscape & Market Catalog | dev.to | 2025-10-26

17. falconpy

    15 30 443 9.4 Python

    The CrowdStrike Falcon SDK for Python

    

18. azure-iot-sdk-python

    16 2 434 6.0 Python

    A Python SDK for connecting devices to Microsoft Azure IoT services

    

19. kosong

    17 1 394 9.2 Python

    The LLM abstraction layer for modern AI agent applications.

    

    Project mention: Kosong: Kimi AI's Agent SDK | news.ycombinator.com | 2025-11-08

20. pan-os-python

    18 6 378 3.7 Python

    The PAN-OS SDK for Python is a package to help interact with Palo Alto Networks devices (including physical and virtualized Next-generation Firewalls and Panorama). The pan-os-python SDK is object oriented and mimics the traditional interaction with the device via the GUI or CLI/API.

    

21. py-stellar-base

    19 2 367 8.6 Python

    Stellar client library for the Python language

    

22. flytekit

    20 2 297 9.4 Python

    Extensible Python SDK for developing Flyte tasks and workflows. Simple to get started and learn and highly extensible.

    

23. msgraph-sdk-python-core

    21 4 276 9.3 Python

    Microsoft Graph client library for Python

    

24. amadeus-python

    22 2 248 5.3 Python

    Python library for the Amadeus Self-Service travel APIs

    

    Project mention: Transform Your Travel Offerings With the TravelPayouts API | dev.to | 2025-09-03

    Amadeus API: Offers robust flight and hotel data but typically requires higher technical expertise to implement. Amadeus provides deeper airline industry integrations but may have higher access barriers for smaller developers.

25. cascadeflow

    23 3 202 9.7 Python

    Smart AI model cascading for cost optimization

    

    Project mention: N8n community node – cascadeflow, Reduce AI costs 30-65% with model cascading | news.ycombinator.com | 2025-11-07

    4. If not, escalate to an expensive "verifier" model

    We're seeing 40-85% cost savings in production workflows, with 70-80% of queries never touching the expensive model.

    Available for Python and TypeScript, with integrations for n8n and LiteLLM. MIT licensed.

    GitHub: https://github.com/lemony-ai/cascadeflow

    This is Day 2 of our release sprint. Would love to hear your feedback, especially if you're dealing with high AI API costs or running models on resource-constrained environments.

26. SaaSHub

    www.saashub.com featured

    SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

    

Python SDK related posts

• Introducing SuperQuantX: Foundational Research for Quantum and Agentic AI

  5 projects | dev.to | 12 Sep 2025

• Transform Your Travel Offerings With the TravelPayouts API

  1 project | dev.to | 3 Sep 2025

• One Input, Multiple AI Minds: Meet the New MultiMindSDK LLM Router

  1 project | dev.to | 11 Jul 2025

• ⚡ One Prompt, Many Brains: How MultiMindSDK Lets You Switch Between LLMs Seamlessly

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• How I Built an Agentic RAG Application to Brainstorm Conference Talk Ideas

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• 🛠️ From LLM to Action Agent: How We Gave ChatGPT Superpowers with ToolAgent (MultiMindSDK)

  1 project | dev.to | 2 Jul 2025

• 💡 Use FederatedRouter to Switch Between GPT-4, Gemini, and Mistral in One AI Agent (Open Source)

  1 project | dev.to | 1 Jul 2025
• A note from our sponsor - SaaSHub
  www.saashub.com | 16 Nov 2025

  SaaSHub helps you find the best software and product alternatives Learn more →

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