Top 23 Python vector-database Projects

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1. llama_index

   1 82 45,183 9.9 Python

   LlamaIndex is the leading framework for building LLM-powered agents over your data.

   

   Project mention: How to Build a RAG Solution with Llama Index, ChromaDB, and Ollama | dev.to | 2025-11-04

   Step 2: Set up LlamaIndex and Chroma DB

2. Stream

   getstream.io featured

   Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.

   

3. mem0

   2 13 42,849 9.8 Python

   Universal memory layer for AI Agents; Announcing OpenMemory MCP - local and secure memory management.

   

   Project mention: Write an Agent | news.ycombinator.com | 2025-11-06

4. txtai

   3 392 11,819 9.4 Python

   💡 All-in-one open-source AI framework for semantic search, LLM orchestration and language model workflows

   

   Project mention: The AI-Native GraphDB + GraphRAG + Graph Memory Landscape & Market Catalog | dev.to | 2025-10-26

   GitHub: https://github.com/neuml/txtai

5. memvid

   4 10 10,372 7.5 Python

   Video-based AI memory library. Store millions of text chunks in MP4 files with lightning-fast semantic search. No database needed.

   

   Project mention: Friday Links #30 — JavaScript Updates, Tools, and Inspiration | dev.to | 2025-10-17

   memvid - Video-based AI memory library. Store millions of text chunks in MP4 files with lightning-fast semantic search. No database needed.

6. deeplake

   5 15 8,894 6.3 Python

   Database for AI. Store Vectors, Images, Texts, Videos, etc. Use with LLMs/LangChain. Store, query, version, & visualize any AI data. Stream data in real-time to PyTorch/TensorFlow. https://activeloop.ai

   

   Project mention: What I Learned Comparing Zilliz Cloud and Deep Lake for Scalable Vector Search | dev.to | 2025-06-09

   As I scaled up a semantic search engine for multi-modal content, I found myself at a fork in the road. Should I lean into a purpose-built vector database like Zilliz Cloud, or embrace a more flexible data lake approach with Deep Lake? These tools promise vector search at scale—but they come from fundamentally different architectural philosophies.

7. cognee

   6 13 8,223 9.9 Python

   Memory for AI Agents in 6 lines of code

   

   Project mention: The AI-Native GraphDB + GraphRAG + Graph Memory Landscape & Market Catalog | dev.to | 2025-10-26

   URLs: https://github.com/topoteretes/cognee (hosted at cognee.ai / Cogwit)

8. deep-searcher

   7 2 7,138 9.4 Python

   Open Source Deep Research Alternative to Reason and Search on Private Data. Written in Python.

   

   Project mention: Deep Searcher, Open source deep researcher on your private data | news.ycombinator.com | 2025-02-21

   github https://github.com/zilliztech/deep-searcher

9. InfluxDB

   www.influxdata.com featured

   InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.

   

10. airweave

    8 4 5,116 10.0 Python

    Context retrieval for AI agents across apps and databases

    

    Project mention: Launch HN: Airweave (YC X25) – Let agents search any app | news.ycombinator.com | 2025-09-30

11. LEANN

    9 4 4,367 9.8 Python

    RAG on Everything with LEANN. Enjoy 97% storage savings while running a fast, accurate, and 100% private RAG application on your personal device.

    

    Project mention: First lightweight local semantic search MCP for Claude Code | news.ycombinator.com | 2025-08-15

    @Berkeley SkyLab, we’re the first to bring semantic search to Claude Code with a fully local index in a novel, lightweight structure — check it out at LEANN(https://github.com/yichuan-w/LEANN).

12. raptor

    10 5 1,374 5.7 Python

    The official implementation of RAPTOR: Recursive Abstractive Processing for Tree-Organized Retrieval

    

    Project mention: Graph RAG의 모든 것 | dev.to | 2025-04-20

    3.2. RAPTOR: Recursive Abstractive Processing for Tree-Organized Retrieval (Stanford Univ, 2024)

13. pymilvus

    11 2 1,296 9.4 Python

    Python SDK for Milvus Vector Database

    

14. pixeltable

    12 7 1,229 9.7 Python

    Pixeltable — Data Infrastructure providing a declarative, incremental approach for multimodal AI workloads.

    

    Project mention: Stop Gluing Data Infrastructure Tools: Build Multimodal AI Workloads and Application with One Declarative Python SDK | dev.to | 2025-07-06

    Star us on GitHub: https://github.com/pixeltable/pixeltable

15. SeaGOAT

    13 7 1,218 9.5 Python

    local-first semantic code search engine

    

16. qdrant-client

    14 2 1,132 8.5 Python

    Python client for Qdrant vector search engine

    

17. NeumAI

    15 2 861 8.7 Python

    Neum AI is a best-in-class framework to manage the creation and synchronization of vector embeddings at large scale.

    

18. rag-demystified

    16 3 854 8.2 Python

    An LLM-powered advanced RAG pipeline built from scratch

    

19. mcp-memory-service

    17 1 852 9.9 Python

    Universal MCP memory service with semantic search, multi-client support, and autonomous consolidation for Claude Desktop, VS Code, and 13+ AI applications

    

    Project mention: Supercharging Productivity with Cursor AI: A React Developer's Guide to MCP Servers and JSON Prompts | dev.to | 2025-04-17

    Key Takeaway: cursor10x-mcp and Repomix excel for speed and context. MCP Memory Service is great for quick wins, and Pieces organizes prompts. But tools alone don’t cut it—prompts are the real magic.

20. llmflows

    18 1 704 0.0 Python

    LLMFlows - Simple, Explicit and Transparent LLM Apps

    

21. vectordb

    19 1 631 7.9 Python

    A Python vector database you just need - no more, no less. (by jina-ai)

    

22. langchain-chatbot

    20 1 433 2.9 Python

    AI Chatbot for analyzing/extracting information from data in conversational format.

    

23. GradCache

    21 1 409 4.5 Python

    Run Effective Large Batch Contrastive Learning Beyond GPU/TPU Memory Constraint

    

24. redis-vl-python

    22 1 341 9.2 Python

    Redis Vector Library (RedisVL) -- the AI-native Python client for Redis.

    

25. vector-db-benchmark

    23 6 340 8.2 Python

    Framework for benchmarking vector search engines

    

26. SaaSHub

    www.saashub.com featured

    SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

    

Python vector-database related posts

• Search Types in Cognee

  1 project | dev.to | 20 Oct 2025

• Cognee: Building the Next Generation of Memory for AI Agents (OSS)

  1 project | dev.to | 17 Oct 2025

• Launch HN: Airweave (YC X25) – Let agents search any app

  1 project | news.ycombinator.com | 30 Sep 2025

• Show HN: Vectorless RAG

  6 projects | news.ycombinator.com | 27 Aug 2025

• Show HN: Airweave – Let agents search any app

  1 project | news.ycombinator.com | 12 May 2025

• Ingest (almost) any non-PDF document in a vector database, effortlessly

  4 projects | dev.to | 25 Apr 2025

• 13 GitHub Projects that Supercharge Your AI and Development Journey 🚀

  11 projects | dev.to | 3 Mar 2025
• A note from our sponsor - Stream
  getstream.io | 15 Nov 2025

  Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure. Learn more →

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