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Tenofovir disoproxil is an oral prodrug of tenofovir that is used as an antiviral drug. It has a bioavailability of 25% and a chemical formula of C19H30N5O10P. Tenofovir itself has a protein binding of less than 1%, an elimination half-life of 17 hours, and is excreted through the kidneys. Its chemical formula is C9H14N5O4P.

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Muhammad Umer Farooq
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60 views1 page

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Tenofovir disoproxil is an oral prodrug of tenofovir that is used as an antiviral drug. It has a bioavailability of 25% and a chemical formula of C19H30N5O10P. Tenofovir itself has a protein binding of less than 1%, an elimination half-life of 17 hours, and is excreted through the kidneys. Its chemical formula is C9H14N5O4P.

Uploaded by

Muhammad Umer Farooq
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Tenofovir disoproxil

Clinical data
Trade names Viread, others
Synonyms Tenofovir disoproxil fumarate, Bis(POC)PMPA
Pharmacokinetic data
Bioavailability 25%
Chemical and physical data
Formula C19H30N5O10P
Molar mass 519.443 g/mol
3D model Interactive image (https://chemapps.stolaf.edu/jmol/jmol.php?model=C%5BC%40H%5D%28Cn1c
(JSmol)
nc2c1ncnc2N%29OCP%28%3DO%29%28OCOC%28%3DO%29OC%28C%29C%29OCOC%2
8%3DO%29OC%28C%29C)

Tenofovir

Clinical data
Synonyms 9-(2-Phosphonyl-methoxypropyly)adenine (PMPA)
Routes of Oral
administration
Pharmacokinetic data
Protein < 1%
binding
Elimination 17 hours
half-life
Excretion Kidney
Chemical and physical data
Formula C9H14N5O4P
Molar mass 287.213 g/mol
3D model Interactive image (https://chemapps.stolaf.edu/jmol/jmol.php?model=O%3DP%28O%29%28O%2
(JSmol)
9CO%5BC%40H%5D%28C%29Cn1c2ncnc%28c2nc1%29N)

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