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Drug Study

This document summarizes a drug study for metformin and linagliptin. It provides information on the dosage, mechanism of action, indications, adverse reactions, and nursing responsibilities for each drug. Metformin is prescribed for type 2 diabetes to decrease glucose production and absorption in the liver and intestines, enhancing glucose uptake. Linagliptin inhibits the DPP-4 enzyme involved in degrading incretin hormones, increasing insulin secretion and lowering glucagon levels to improve glucose homeostasis. Nurses are responsible for monitoring patients for hypoglycemia, changes in pancreatic enzymes, and side effects like diarrhea, nausea, and vomiting.
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0% found this document useful (0 votes)
276 views2 pages

Drug Study

This document summarizes a drug study for metformin and linagliptin. It provides information on the dosage, mechanism of action, indications, adverse reactions, and nursing responsibilities for each drug. Metformin is prescribed for type 2 diabetes to decrease glucose production and absorption in the liver and intestines, enhancing glucose uptake. Linagliptin inhibits the DPP-4 enzyme involved in degrading incretin hormones, increasing insulin secretion and lowering glucagon levels to improve glucose homeostasis. Nurses are responsible for monitoring patients for hypoglycemia, changes in pancreatic enzymes, and side effects like diarrhea, nausea, and vomiting.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Drug Study

Name of Patient: Attending Physician:


Age: Ward/Bed Number: Impression/ Diagnosis:

Dosage, Route,
Name of Drug Frequency and Mechanism of Action Indication Adverse Reactions Special Precautions Nursing Responsibilities
Timing

Generic: Dosage: Increases insulin concurrent use with Hyperglycemic rebound; Use cautiously in: Administer with a meal.
metformin sensitivity by decreasing insulin in type 2 Lactic acidosis ● renal impairment, Monitor blood glucose level closely
500 mg/tab 1 tab glucose production and diabetes mellitus myocardial infarction, Monitor kidney and liver function
absorption in liver and chronic alcohol use tests, particularly in elderly
Brand: intestines and enhancing ● elderly or patients.
Riva-Metformin Route: glucose uptake and debilitated patients Periodically monitor glucose and
Po utilization glycosylated hemoglobin levels to
evaluate drug efficacy.
Teach patient about diabetes and
importance of proper diet,
Frequency: exercise, weight control, and
Od blood glucose monitoring.
Inform patient that drug may
Classification Contraindications Side Effects cause diarrhea, nausea,and upset
stomach.
Functional: Timing: Hypersensitivity to drug Diarrhea ,nausea ,
Hypoglycemic 8 vomiting ,abdominal
agent bloating unpleasant
Chemical: metallic taste
biguanide
Drug Study
Name of Patient: Attending Physician:
Age: Ward/Bed Number: Impression/ Diagnosis:

Dosage, Route,
Name of Drug Frequency and Mechanism of Action Indication Adverse Reactions Special Precautions Nursing Responsibilities
Timing

Generic: Dosage: Linagliptin is an inhibitor Glycemic control in Hypersensitivity reaction; Use cautiously in:  Assess for drug allergies.
Linagliptin + of the enzyme DPP-4 patients with Type 2 pancreatitis; ● renal impairment,  Assess for recent history of
Metformin 2.5/500 mg/tab, (Dipeptidyl peptidase 4) DM nasopharyngitis myocardial infarction, alcohol intake.
1 tab an enzyme which is chronic alcohol use  Assess for signs and
involved in the ● elderly or symptoms of
inactivation of the incretin debilitated patients hypoglycemia.
Brand: Route: hormones GLP-1 and GIP  Monitor for changes in
Trajenta Duo Po (glucagon-like peptide-1, pancreatic enzyme levels.
glucose-dependent  Encourage small frequent
insulinotropic meals for anorexia.
polypeptide). These  Promote fluid intake for
Frequency: hormones are rapidly cough. Avoid cold water.
Od degraded by the enzyme  Encourage bed rest for
Classification DPP-4. Both incretin Contraindications Side Effects nausea. Promote client
hormones are involved in safety.
Functional: the physiological Hypersensitivity to drug Cough; anorexia; nausea,  Monitor I & O for vomiting
Antihyperglycemic Timing: regulation of glucose and its component vomiting; diarrhea and diarrhea. Replace fluid
agent 8 homeostasis. Linagliptin loss
glucose-dependently
Chemical: increases insulin secretion
Purine and and lowers glucagon
quinazoline secretion thus resulting in
derivative an overall improvement in
the glucose
homoeostasis.

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