PHARMACEUTICS IA
(PHYSICAL PHARMACY)
PHM 6101
LECTURE # 1
FATIMA NASIM
Sr Lecturer
Faculty of Pharmacy,
Ibadat International University,
Islamabad
COURSE OUTLINE
PHARMACY ORIENTATION: Introduction and
orientation to the Profession of Pharmacy in relation to
Hospital Pharmacy, Retail Pharmacy, Industrial
Pharmacy, Forensic Pharmacy, Pharmaceutical
education and research etc.
2. HISTORY AND LITERATURE OF PHARMACY: a. A
survey of the history of pharmacy through ancient
Greek and Arab periods with special reference to
contribution of Muslim scientists to pharmacy and allied
sciences. b. An introduction of various official books.
COURSE OUTLINE
3. PHYSICO-CHEMICAL PRINCIPLES:
a. Solutions: Introduction, types, concentration
expressions, ideal and real solution, colligative
properties, their mathematical derivations and
applications in pharmacy, molecular weight
determinations, distribution co-efficient and its
applications in pharmacy.
b. Solubilization: Factors affecting solubility.
Surfactants, their properties and types. Micelles;
their formulation and types.
COURSE OUTLINE
c. Adsorption: Techniques and processes of
adsorption in detail.
d. Ionization: pH, pH indicators, pka, buffers, buffer‟s
equation, isotonic solutions and their applications in
pharmacy
e. Hydrolysis: Types and protection of drugs against
hydrolysis.
f. Micromeritics: Particle size, shapes and distribution
of particles. Methods of determination of particle size
and importance of particle size in Pharmacy.
COURSE OUTLINE
4. DISPERSIONS: a. Colloids: Types, methods of
preparation, properties (optional, kinetic,
electrical). Dialysis and artificial kidney, stability of
colloids, protection and sensitization phenomenon
and application of colloids in Pharmacy.
b. Emulsions: Types, theories of emulsification,
emulsifying agents their classification and stability
of emulsion.
c. Suspensions: Type, Methods of Preparation,
Properties, Suspending agents, their classification
and stability
LIST OF RECOMMENDED
BOOKS
S P Agarwal, Rajesh Khanna Physical Phramacy ,
2nd edition
Cooper JW, Gunn C, Carter SJ. Cooper and Gunn‟s
Tutorial Pharmacy.
Sinko PJ, Martin AN. Martin's physical pharmacy
and pharmaceutical sciences: physical chemical
and biopharmaceutical principles in the
pharmaceutical sciences.
Bentley textbook of Pharmaceutics
Remington: The science and practice of pharmacy.
23rd Ed. Academic Press, 2020.
PHARMACY
ORIENTATION
Contents
Pharmacy
Pharmacist
Drugs
PHARMACY
is derived from the Greek work „Pharmakon‟,
meaning drug.
The word „Pharmacy‟ has two meanings :
General sense – it is a place where drugs or
medicines are sold.
Professional sense – it is the profession, the
members of which deal with drugs.
PHARMACY
Art and science of preparing and dispensing medications
and the provision of drug and related information to the
public.
Pharmacy
Clinical health science that links medical sciences
with chemistry and it includes the discovery,
production, disposal, safe and effective use and
control of medications and drugs.
New Pharmacy
Pharmacist
The person who is licensed to prepare and
dispense drug.
"Pharmacist is the drug expert“
What do Pharmacists do?
Pharmacists are experts in medicines and as one
of the fastest growing areas of healthcare play a
key role in improving the health of the nation, and
ensuring patient safety.
They work in a number of different settings:
develop new medicines
supply medicines
provide advice about medicines
offer health services.
Other roles of Pharmacist
Pharmacists also work in other roles where there
may be less direct contact with patients, for
example in universities, regulation, government
organisations, research, publishing and the
pharmaceutical industry.
Continued
Pharmacists are experts in medicines and their
use.
They have a unique set of skills and knowledge,
they train as scientists and clinicians.
They use this scientific knowledge to advise
patients how to take their medicines and make
recommendations on the best medicine for
particular conditions and diseases.
Continued
Pharmacists are the third largest healthcare
profession in Great Britain.
They work in a number of different settings,
developing new medicines, supplying medicines,
providing advice about medicines, and offering
health services.
Some pharmacists are also prescribers, and like
doctors can prescribe medicines on prescriptions.
Continued
They also work within the wider healthcare team,
ensuring that patients receive the best possible
care.
Continued
Pharmacists must have very good communication
skills, as they are required to translate technical
medical information to patients.
They often work in busy environments and must be
organised, logical, be able to manage multiple
tasks, and remain calm under pressure.
Continued
They should also have a good eye for detail and
be thorough and accurate in what they do.
Pharmacists work in teams and are often involved
in education and training others, so good people
skills are also essential.
Drug
A drug is any substance that acts on the living body to
alter the physiological process and are used for the
prevention, diagnosis and treatment of diseases.
Drug
Any chemical compound (natural or synthesized)
that may be used by human or animal as an aid in
the diagnosis, treatment, or prevention of disease.
Examples
Radioactive compounds
Aspirin
Paracetamol
Mefenamic acid
Medicine
A medicine is any drug which has a definite form &
dose and are therapeutically used for the treatment
of diseases of living subjects.
Why choose Pharmacy?
A dynamic, people-oriented career in health care.
Diverse employment opportunities.
A flexible work environment.
A comfortable income.
Be part of a respected profession.
What are the pros and cons?
Pros
Job security
Flexible working
Excellent rewards
Transferable skills
Variety
Opportunities in new roles/settings
Opportunities to specialise
Cons
Competitive
Long hours in certain sectors and
Evening/weekend shifts
Physically demanding in certain sectors
E Pharmacy
The application of internet to access drugs and
diagnostics which begin early in advent of info age
has matured into portals or virtual drugs stores
popularly known as “Internet pharmacy” or “Online
pharmacy” or “Web pharmacy” or “Cyber
pharmacy”.
Continued
e-Pharmacies are online platforms where
consumers can purchase medicines without having
to visit brick-and-mortar pharmacies.
This makes the process more convenient for
consumers and has resulted in a rising demand for
the model across the world.
In addition, increasing utilization of e-
Prescriptions in the hospitals, globally, it has also
led to the growth of this industry.
Advantages of E Pharmacy
Disadvantages of E PHARMACY
Where can a Pharmacist work?
Community Pharmacy
Hospital Pharmacy
Industrial Pharmacy
Primary Care Pharmacy
Academic Pharmacy
Military Pharmacists
Regulatory Affairs
References
“The science and Pharmacy” by Gennaro Alfonso
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562902/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093426/