Basic sciences

Anatomy
1. Coronary arteries (4)
2. Coronary circulation
3. Mediastinum (3)
4. Extraocular muscles (2)
5. Pleura, along with nerve supply and blood supply
6. Bronchopulmonary segments (8)
7. Foetal circulation (2)
8. Median nerve in the hand
9. Circle of Willis (4)
10. Arterial supply to brain
11. Blood supply of spinal cord (4)
12. CN 7 (5)
1. Pituitary gland (2)
13. Pituitary adenoma
14. Portal circulation (2)
15. Portal vein
16. Bowman’s capsule (2)
17. Pericardium
18. CN 3 (3)
19. Adrenal gland
20. Spleen
21. Urinary bladder nerve supply and neurogenic bladder (9)
22. Physiology of micturition (3)
23. Parathyroid gland (2)
24. Development of pancreas
25. Pancreas structure (2)
26. Pancreatic enzymes
27. Venous drainage of brain
28. CN 2
29. Thyroid gland anatomy and histology (2)
30. Relations and blood supply of thyroid gland
31. Relations, lobes, blood supply of prostate
32. Glomerulus
33. Blood supply to liver
34. Macroscopic structure of liver
35. Histology of liver (2)
36. Anatomy and histology of liver
37. Vascular segments of liver
38. Collecting system of kidney
39. Muscles of respiration (2)
 40. Right atrium
41. Left ventricle
42. Microscopic structure of lung
43. Vagus nerve
44. Development of spleen
45. Development of heart
46. Development of right atrium
47. Development of interatrial septum
48. Base of heart (2004)
49. Structure of suprarenal gland
50. Internal capsule – composition and blood supply (3)
51. Pyramidal tract (2)
52. Microscopic structure of kidney (2)
53. Lymphatics of lung (2)
54. Meckel’s diverticulum
55. Development of lung
56. Cavernous sinus (2)
57. Speech centre and its lesions
58. Recurrent laryngeal nerve lesions
59. Venous drainage of rectum and anal canal
60. Nerve supply to tongue
61. Name the intrinsic muscles of the hand
62. Development of arch of aorta
63. Cervico-thoracic ganglion
64. Muscles of mastication
65. Conduction system of heart and blood supply
66. Nuclear masses of thalamus
67. Porto-caval anastomoses and clinical importance (2)
68. Inguinal canal

Physiology
1. Erythropoietin (3)
2. Erythropoiesis (2)
3. Somatostatin
4. Atrial natriuretic factor
5. NMJ
6. Insulin receptor
7. Calcitonin
8. Blood brain barrier (3)
9. Counter-current mechanism (2)
10. Pulmonary function tests (2)
11. Measurement of cardiac output (2)
12. Iron metabolism (4)
13. Temperature regulation (4)
14. Physiology of consciousness (3)
15. Physiology of aerobic exercise
16. Sympatho-adrenal system physiology
17. Hypothalamo-pituitary axis (2)
18. Ventilation-perfusion quotient (2)
19. Renin-angiotensin-aldosterone system (4)
20. Cardiogenic shock – pathophysiology and management (2)
21. Syndrome of shock
22. Compensatory response of organs in hypovolaemic shock
23. Gastric secretion and their hormones
24. Gut hormones (2)
25. Conduction system of heart and ECG (3)
26. Erythropoiesis and its regulation
27. Fat metabolism
28. Coagulation of blood (2)
29. Surfactant
30. Enzymes involved in protein digestion
31. Cough reflex
32. Bile acids
33. Bile pigment metabolism (2)
34. Tests of gastric function
35. Carbohydrate digestion
36. Control of respiration
37. Action potential and its applied physiology
38. Hydrochloric acid secretion in stomach
39. Splanchnic circulation
40. Ventricular remodelling
41. Endocrine functions of pancreas
42. Sleep disorders
43. REM sleep
44. B lymphocyte functions
45. T lymphocyte
46. Mechanisms of deglutition
47. Functions of neutrophils
48. Cardiac cycle
49. Physiology of oedema formation
50. Gastrocolic reflex
51. Functions of platelets
52. Prolactin
53. Apoptosis (2)
54. Regulation of cardiac output
55. Interferons
56. Myocardial contractility
57. Functions of cerebellum
58. Reticular activating system in EEG
 59. Gastric mucosal barrier
60. Physiological basis of polyphagia, polydipsia, polyuria
61.

Biochemistry
1. Functions of parathyroid gland
2. PTH functions (2)
3. Control of thyroid secretion (2)
4. PT
5. Hypertriglyceridaemia
6. Fatty liver
7. Tocopherol
8. Immunoglobulins (4)
9. Jaundice (2)
10. LFT (2)
11. RFT (3)
12. Unconjugated hyperbilirubinaemia
13. Oral glucose tolerance test (2)
14. Acid-base balance
15. Essential fatty acids
16. Hypercalcaemia due to malignancy
17. Porphyrin metabolism
18. Glucose-6-phosphate dehydrogenase
19. G6PD deficiency (3)
20. Plasma proteins
21. HbA1C (2)
22. Acid phosphatase – isoforms and function (2)
23. ABG in respiratory diseases
24. Essential amino acids
25. Vitamin E
26. Vitamin A
27. Vitamin A deficiency
28. Vitamin D – new concepts (2)
29. Fat soluble vitamins
30. Vitamin K
31. Prostaglandins (4)
32. Plasma enzyme in disease
33. Kreb’s cycle
34. Glycogenesis
35. Glycogenolysis
36. Gluconeogenesis
37. Glycolysis
38. Uric acid metabolism in health and disease (2)
39. Biological markers of malignancy
 40. Fibrinolytic system
41. Markers of AKI
42. Urine tests for inborn errors of metabolism
43. Secretory functions of liver
44. Growth hormone stimulation test
45. Alkaline phosphatase
46. Vitamin B12
47. PUFA
48. Coris cycle or lactic acid cycle
49. Bilirubin metabolism
50. CRP
51. Leukotriene modifiers (2)
52. Western blot
53. Non-protein nitrogenous compounds
54. Biological significance of fats
55. Classification of amino acids
56. Brief note on enzymes of clinical interest
57. Buffer systems in blood
58. Phenylketonuria
59. Alkaptonuria
60. Physiology of ejaculation
61. Cytometrogram
62. Balanced diet for the adult man (vegetarian) (2003)
63. Reducing substances other than glucose
64. Acid load test
65. Inhibitors of Na/K ATPase
66. Ketone bodies
67. Cholesterol turnover
68. Genetic code
69. Lipoproteins
70. Isoenzymes of clinical importance
71. Biochemical importance of homocysteine
72. Isomers
73. Acquired chromosome abnormalities

Microbiology
1. Plasmodium falciparum
2. Paramyxovirus
3. Bio-terrorism (3)
4. Atypical mycobacteria
5. CMV
6. Cestode infestation
7. Tapeworm
8. Hepatitis C virus (2)
 9. Candidiasis
10. Chikungunya virus
11. Autoclave
12. PCR in medicine (2)
13. Complement system
14. Serological tests for syphilis (2)
15. Life cycle of hookworm
16. Structure and classification of dengue virus
17. Hand washing
18. “Pathologic species and diagnostic laboratory tests”
19. Pro-inflammatory cytokines
20. Cytokines (2)
21. Serological diagnosis of ebola
22. Lab tests for atypical mycobacteria
23. Transport media
24. Serology of hepatotrophic viruses
25. Parvovirus infection
26. Zika infection
27. Pasteurisation
28. Cellular immunodeficiency diseases
29. Post-streptococcal sequelae
30. Uses of E. coli
31. Serological tests of CSF
32. Naglers reaction

Pharmacology
1. Beta lactamase inhibitors
2. Digoxin
3. Insulin resistance (2)
4. Methotrexate
5. Tricyclic antidepressants
6. Adverse effects and uses of aspirin
7. Aspirin resistance
8. Classification of anti-hypertensive drugs
9. DOTS therapy
10. Anti-amoebic drugs (2)
11. Drug addiction (2)
12. Antimitotics
13. Nitric oxide (2)
14. Drug interactions
15. Sulfasalazine
16. Vitamin excess
17. Newer quinolones
18. Anti-malarial drugs
19. Chloroquine
20. Radio-active iodine
21. Benzodiazepines
22. Anti-viral agents (2)
23. Anti-retroviral drugs (2)
24. Anti-helminthics (2)
25. Anti-arrhythmics (2)
26. Coagulants and anti-coagulants
27. Anti-thyroid drugs
28. Amiodarone
29. Indapanide
30. Quinine
31. Vancomycin
32. Newer anti-platelet drugs
33. Newer macrolides (2)
34. Side effects of carbamazepine
35. Clinical advantages of carbidopa
36. ARBs
37. Azithromycin – indications, adverse reactions
38. Bosentan
39. Carbapenems
40. Daptomycin – indications and adverse reactions
41. Sodium nitroprusside
42. ACE inhibitors
43. ARBs
44. Newer antidepressants
45. Tolvaptan
46. Newer antimalarials
47. H1 blockers
48. H2 blockers
49. Stem cell therapy (2)
50. Classify diuretics, add note on metolazone
51. Loop diuretics
52. Furosemide
53. Forced diuresis
54. Biologic therapy in treatment of malignancy
55. Tenofovir
56. Orciprenaline
57. Rate controlling CCBs
58. Gut sterilisers
59. Newer anxiolytics
60. Rifampin
61. Ivermectin (2)
62. Tafenoquine
63. Vasodilators in CCF
 64. Drug therapy in pulmonary hypertension
65. Choice of anaesthetic agents in coronary patients (2003)
66. Anti-pseudomonal agents
67. Ganciclovir
68. Repaglinide

Pathology
1. Cerebral embolism
2. Myeloma kidney
3. Molecular genetics of lung carcinoma
4. Non-bacterial thrombotic endocarditis
5. Tumour markers (6)
6. Reid Sternberg giant cell
7. Non-caseating granuloma
8. Bridging necrosis (2)
9. Cancer genetics
10. Type IV hypersensitivity
11. Types of emphysema
12. Pathology of emphysema in a non-smoker
13. Anaphylaxis (2)
14. Treatment of anaphylaxis
15. Atherosclerotic plaque
16. Acute hepatitis – gross structure and microscopic appearance
17. Structural lesions in chronic bronchitis
18. Silicosis and lung
19. Pathology of acute lung injury
20. Primary intracranial tumours
21. Pathology of Hodgkins lymphoma
22. Pathology of Rickettsial infections
23. Pathological changes in stages of consolidation of lung (lobar pneumonia)
24. Pathology in cirrhosis of liver
25. Pathology in rheumatic carditis
26. Pathology of ulcerative colitis
27. Pathology of pernicious anaemia
28. RBC indices
29. Nutmeg liver
30. Pathological calcification
31. Heat shock proteins
32. T helper cells
33. Suppressor T cell
34. FISH
35. Hamartomas
Pulmonology
Essay
1. Types of respiratory failure
2. Classify different parenchymal lung diseases. Describe clinical features and management of
interstitial pneumonias
3. Aetiology, pathophysiology, clinical features, management of cystic lung disease
4. Define Bronchial asthma. Aetiology, pathogenesis, manifestations, complications, diagnosis
and management of bronchial asthma. Note on acute severe asthma. Newer anti-asthmatic
drugs (2)
5. Aetiopathogenesis, clinical features, management and investigations of pulmonary
thromboembolism (2)
6. Clinical features, diagnosis and management of acute pulmonary embolism
7. MDR TB (3)
8. Management of COPD
9. Pathogenesis, clinical features, diagnosis, treatment of nosocomial pneumonia (2)
10. Agents, risk factors, clinical features, treatment of pneumonia (2)
11. Aetiology, pathophysiology, clinical features, management of pleural effusion
12. Aetiology, clinical features, management of obstructive sleep apnoea
13. Mechanisms causing non-cardiogenic pulmonary oedema and management of ARDS
14. Aetiology, clinical features, diagnosis, treatment of empyema thoracis

Short notes
1. Extrapulmonary TB
2. Clinical features of disseminated tb
3. Miliary tuberculosis
4. Pulmonary complications of tuberculosis
5. Multi-resistant Mycobacterium tuberculosis (2)
6. Ziehl Neelson staining and reporting scale for M. tb
7. Serological tests of tuberculosis (2)
8. Lab diagnosis of TB (2)
9. Management of MDR TB (4)
10. Chemoprophylaxis of TB
11. Lobar pneumonia
12. Bronchopulmonary aspergillosis (2)
13. Aspergillosis (2)
14. Pathology of bronchiectasis
15. Pulmonary eosinophilic syndromes
16. Primary pulmonary hypertension
17. Treatment of obstructive sleep apnoea
18. OSAS
19. VAP
 20. Preventive strategies for VAP
21. Lung abscess
22. Yellow nail syndrome
23. Pneumocystis infection (4)
24. Anaerobic infections of lung and pleura
25. Community acquired pneumonia (2)
26. Pulmonary embolism
27. Primary complex
28. Causes and management of recurrent spontaneous pneumothorax
29. Radiological presentation and clinical classification of bronchogenic carcinoma
30. Interpretation of lung function tests
31. Indications for pulmonary function tests
32. Pancoast tumour
33. Indicators of obstructive lung disorders
34. Management of acute severe asthma
35. Drug-induced lung diseases
36. PFT in emphysema lung
37. Second line ATT drugs
38. Mesothelioma
39. Acute lung injury
40. RNTCP
41. Complications of Pneumococcal pneumonia
42. Newer drugs in BA
43. FoB
44. Non-pulmonary manifestations of cystic fibrosis

Gastroenterology
Essay
1. Ulcerative colitis – aetiopathogenesis, clinical features, investigations, management (2)
2. Pathogenesis of peptic ulcer, diagnosis, treatment and prevention
3. Aetiology, pathophysiology, clinical features, management of viral gastroenteritis
4. Differential diagnosis, investigations, and treatment in an individual aged about 30 years
coming with chronic diarrhoea
5. Aetiology, pathogenesis, course of disease, lab diagnosis, treatment, complications of acute
pancreatitis (3)
6. Definition, clinical features, aetiopathogenesis, diagnosis, management of IBS
7. Enumerate the functional bowel disorders. Describe the diagnostic criteria, pathophysiology,
and recent advances in the therapy of IBS
8. Mention risk factors for H. pylori infection. Outline the bacterial and host factors important
in determining H. pylori-induced gastrointestinal disease. Summarise the potential
mechanisms by which H. pylori may lead to gastric secretory abnormalities. Describe the
recent concepts in the management of H. pylori infection
Short notes
1. Ulcerative colitis
2. Crohn’s disease
3. IBD
4. Extra-intestinal manifestations of IBD
5. Medical management of IBD
6. Malabsorption syndrome (2)
7. Chronic pancreatitis
8. Adverse factors in Acute pancreatitis. Discuss autoimmune pancreatitis
9. Classify chronic gastritis. Note on treatment of H. pylori
10. Role of H. pylori in acid peptic disease (2)
11. H. pylori infection
12. Regimens for elimination of H. pylori
13. Peptic ulcer disease
14. IBS (2)
15. Investigations for chronic diarrhoea
16. Traveller’s diarrhoea (4)
17. Aetiology, investigations and treatment of bacillary dysentery
18. Bacterial food poisoning (3)
19. Food poisoning
20. Abdominal tuberculosis
21. ORS solution
22. Achlorhydria
23. GERD (2)
24. Viral gastroenteritis
25. Motor dysphagia

Hepatology
Essay
1. Aetiology, pathology, clinical features, management, complications of cirrhosis liver (2)
2. Aetiology, pathophysiology, clinical features, management of chronic hepatitis (2)
3. Write about bilirubin metabolism. Classify hepatitis. Discuss hepatitis B virus infection,
natural history, diagnosis, treatment and vaccine (3)
4. Epidemiology, clinical features of hepatitis. Complications and current concepts in
management of hepatitis.

Short notes
1. Noncirrhotic portal fibrosis
2. Cirrhosis liver
3. Alcoholic cirrhosis
4. Alcoholic liver injury
 5. Portal hypertension (2)
6. Classify portal hypertension. Enumerate the causes of extrahepatic portal hypertension
7. Wilson’s disease (3)
8. Evaluation of Wilsons disease
9. Gilbert’s syndrome
10. Congenital hyperbilirubinaemias
11. Drug induced hepatitis
12. Autoimmune hepatitis (2)
13. Hepatitis A
14. Chronic hepatitis B
15. Delta virus of hepatitis
16. Chronic Hepatitis B drug therapy
17. Chronic active hepatitis (2)
18. Hepatitis B vaccination
19. Hepatitis C
20. Hepatocellular carcinoma
21. SAAG
22. Haemochromatosis
23. Indian childhood cirrhosis (2)
24. Non-alcoholic hepatic steatosis (2)
25. Liver transplantation
26. Clinical features and management of hepatic encephalopathy (2)
27. Precipitating factors and management of hepatic encephalopathy
28. HRS
29. Pulmonary manifestations of CLD

Haematology
Essay
1. Classify haemoglobinopathies. Pathophysiology, clinical features, management of any one of
them
2. Aetiology, genetics, pathology, clinical features, management of haemophilia
3. Outline coagulation cascade and describe formation of the haemostatic plug. Approach to
patient with bleeding disorder and management (2)
4. Pathophysiology, haematological and clinical manifestations and management of MDS
5. Stem cell transplant in clinical practice
6. Pathology, clinical manifestations, diagnosis, management of amyloidosis
7. Classify leukaemias. AML – clinical features, pathophysiology, diagnosis, management (3)
8. Iron deficiency anaemia – aetiopathogenesis, clinical features, investigation, management
9. NHL – aetiopathogenesis, clinical features, investigation, management
10. Define anaemia, discuss in detail about megaloblastic anaemia and management
11. Classify haemolytic anaemia. Describe the haemolytic mechanisms, and recognition of
haemolysis
 12. Functions of platelets. Aetiology, clinical features, diagnosis, treatment of ITP (2)
13. Bone marrow in health and disease
14. Aetiology, clinical features, diagnosis, management of aplastic anaemia

Short notes
1. Hodgkin disease (2)
2. NHL (2)
3. ALL
4. AML
5. Chromosomal abnormality in acute leukaemia
6. CML (2)
7. PNH (2)
8. MM
9. Chemotherapy for MM (2)
10. Waldenstrom’s macroglobulinaemia (2)
11. Pure red cell aplasia (PRCA)
12. Haemolytic anaemia
13. Thrombocytopaenia
14. Transfusion haemosiderosis
15. Management of aplastic anaemia
16. Aplastic anaemia
17. Clinical features, lab abnormalities, and management of tumour lysis syndrome
18. Investigation of thrombophilia
19. Dimorphic anaemia
20. Sideroblastic anaemia (2)
21. Causes and management of DIC
22. Management of alpha thalassemia
23. Beta thalassaemia (2)
24. Beta thalassemia major
25. Thalassaemia
26. Bone marrow transplantation
27. Bone marrow failure
28. Polycythaemia (2)
29. Management of anaemia in an 11-year old female child
30. Von Willebrand disease (3)
31. Haemophilia
32. Leukaemoid reaction
33. Burkitt’s lymphoma (2)
34. Sickle cell crisis
35. Sickle cell disease
36. Autologous blood transfusion
37. Iron deficiency anaemia
38. Blood component therapy (2)
39. Haematopoietic growth factors
 40. Essential thrombocytosis
41. Hypercoagulable states
42. Hairy cell leukaemia
43. Philadelphia chromosome
44. Musculoskeletal abnormalities in haemoglobinopathies
45. MALTomas
46. Plummer Wilson syndrome
47. Serum protein electrophoresis (2)
48. Electrophoretic pattern of proteins
49. Systemic mastocytosis

Oncology
Essay
1. Lung cancer – cytologic basis, TNM staging, clinical features, lab findings, management
2. Clinical features, staging, diagnosis, management of renal cell carcinoma
3. Manifestations and management of oncological emergencies (2)

Short notes
1. Small cell lung cancer
2. Renal cell carcinoma
3. Cytokines in oncology

Rheumatology
Essay
1. Aetiology, clinical features and management of dermatomyositis
2. Aetiology, pathophysiology, clinical features, extra-articular manifestations, diagnosis,
management of rheumatoid arthritis (3)
3. Enumerate the various vasculitis syndromes and discuss the clinical features and
management of polyarteritis nodosa
4. Clinical features, diagnosis, treatment of mixed connective tissue disease
5. Pathogenesis, clinical manifestations, pathology, management of SLE (3)
6. Pathogenic mechanisms of vessel damage in vasculitic syndromes. Outline the diagnosis and
clinical features of small vessel vasculitis

Short notes
1. Serological tests for SLE
2. Biologicals used in rheumatoid arthritis (2)
3. DMARDs in RA
 4. Felty’s syndrome
5. Hand in RA
6. DMARDs
7. Biological DMARDs (2)
8. Raynaud’s phenomenon (2)
9. Antiphospholipid antibody syndrome (3)
10. Young onset OA
11. Serum antibodies assay in different rheumatological disorders and its relevance in reactive
arthritis
12. Caplan syndrome
13. Kawasaki disease
14. Crystal associated arthritis
15. Seronegative arthropathy
16. Criteria for RA diagnosis
17. Churg Strauss syndrome (2)
18. Wegener’s granulomatosis
19. HSP (3)
20. Diagnosis and treatment of Sjogrens syndrome
21. Enteropathic arthritis
22. Secondary vasculitis syndrome
23. Vasculitis
24. Ankylosing spondylitis (2)
25. Infliximab
26. Sarcoidosis extrapulmonary manifestations
27. Sarcoidosis
28. Pathological changes of OA. Note on young-onset OA
29. Purpura
30. Reactive arthropathy/Reiters disease (3)
31. Marfans syndrome
32. Polymyositis
33. ANCA
34. Juvenile rheumatoid arthritis
35. Clinical features of syndromes associated with hypoxanthine-guanine-phosphoribosyl-
transferase (HGPRT) deficiency
36. Takayasu disease

Cardiology
Essay
1. Epidemiology, pathogenesis, diagnosis, treatment of rheumatic fever (2)
2. Classify cardiomyopathies. Pathophysiology, clinical features, lab diagnosis and management
of HOCM
3. Aetiology, clinical features, management of dilated cardiomyopathy (2)
 4. Discuss mechanisms of tachyarrhythmias. Causes, classification, clinical features, diagnosis,
management, complications of AF
5. Management of ACS
6. Aetiology, pathophysiology, clinical features, complications, management of pericardial
effusion
7. Constrictive pericarditis – aetiology, pathophysiology, clinical features, diagnosis,
management (2)
8. Pathophysiology, aetiology, clinical features, diagnosis, management of aortic stenosis
9. Structure and functions of normal mitral valve. Aetiology, clinical features, diagnosis and
management of mitral incompetence
10. Pathogenesis of atherosclerosis. Mention the risk factors. Outline the selected clinical trials
of statin therapy for prevention of coronary events
11. Atherosclerosis – aetiopathogenesis, primary and secondary prevention
12. Define cardiac failure. Describe management of cardiac failure (2)
13. Aetiology, clinical features, diagnosis, management of primary diastolic dysfunction of the
heart
14. Classification, aetiology, clinical features, diagnosis, investigations, management of
hypertension in an adult
15. Pathogenesis, classification, clinical features, management of infective endocarditis (2)
16. Management strategy for patients with UA and NSTEMI. Note on pathophysiology of
cardiogenic shock (2)
17. Aetiology, classification, complications of congenital heart disease. Clinical features,
diagnosis, management of patients with ASD
18. Cardiovascular manifestations of nutritional disorders
19. Pathophysiology, aetiology, clinical features, diagnosis, management of AS

Short notes
1. Rheumatic fever
2. Pericarditis
3. Morphology of ASD
4. ASD in an adult
5. Cardiomyopathy
6. Restrictive cardiomyopathy
7. Pansystolic murmur
8. Continuous murmur
9. Blood culture for infective endocarditis
10. Infective endocarditis
11. Prevention of infective endocarditis
12. Role of microbiologist in drug-resistant IE
13. Modified criteria for IE
14. Refractory cardiac failure
15. Resistant hypertension – causes
16. Pathophysiology of primary hypertension. Discuss steps in evaluation of perioperative
hypertension
17. Hypertension in the young – causes
18. Malignant hypertension
19. Constrictive pericarditis
20. Cardiac tamponade
21. Pacemakers in AV conduction disease (2)
22. Pacemakers of the heart
23. Newer therapies for heart failure (3)
24. Levosimendan and usefulness in heart failure
25. Neurohormonal activation and compensatory mechanisms in heart failure
26. Indications and principles of cardiac resynchronisation therapy
27. Clinical presentations of phaeochromocytoma. Approach to diagnosis.
28. Phaeochromocytoma
29. Post-cardiac injury syndrome
30. AF
31. Causes of AF. Note on paroxysmal AF
32. Cor pulmonale
33. Management of UA, NSTEMI
34. VT
35. Management of IE due to enterococci and streptococci
36. Ventricular assist device
37. Re-entrant arrhythmias
38. Drug-eluting stents (2)
39. Stents
40. Interventional management of coronary artery disease
41. Enumerate the therapeutic procedures of recurrent arrhythmia. Note on catheter ablation
42. CT imaging in cardiology
43. Evaluation of myocardial infarct size
44. Ischaemic cardiomyopathy
45. Role of viruses in RHD
46. Treatment of accelerated hypertension
47. Haemodynamics in patent ductus arteriosus after birth
48. Frederickson’s classification of hyperlipoproteinaemias
49. Side effects of beta blockers
50. Cardioselective beta blockers
51. Statins
52. Rosuvastatin – indications, mechanism of action, benefits
53. Pleiotropic effects of statins and the latest controversies associated with its use
54. Fibrates – indications and side effects
55. Drug therapy of resistant hypertension
56. Current status of beta blockers in CCF
57. Hyperlipidaemia (3)
58. Causes of secondary hyperlipidaemia
59. Lipid lowering agents
60. Acute AR
61. Pre-excitation syndrome
 62. Atrial myxoma
63. Aortic stenosis
64. Intra-aortic balloon counterpulsation
65. Defibrillators
66. MVPS
67. Hypotension
68. Newer antiplatelet drugs
69. Ebstein anomaly
70. Interventional management of CAD

Neurology
Essay
1. Discuss the approach to a patient presenting with fever and headache. Describe causes,
diagnosis and management of bacterial meningitis (3)
2. Aetiology, clinical features, management of MS (2)
3. Causes, clinical features, diagnosis and management of hypoxic-ischaemic encephalopathy
4. TB meningitis – aetiopathogenesis, clinical features, diagnosis, management
5. Akinetic rigid syndrome – aetiopathogenesis, clinical features, investigations, management
6. Pathophysiology, clinical features, investigations, management of GBS
7. Discuss the evaluation and management of a 25-year old male brought unconscious to the
emergency room
8. Discuss criteria for brain death and analyse the factors in organ harvesting
9. Discuss in detail the aetiology, clinical features, and management of movement disorders
10. Classification, aetiology, clinical features, diagnosis, investigations, management of epilepsy
(2)
11. Aetiopathogenesis, clinical features, management of parkinsonism
12. Systemic effects of chronic alcohol abuse. Management of alcohol intoxication and
withdrawal
13. Aetiology, clinical features, diagnosis, management of myasthenia gravis
14. Classification, clinical features, management of myopathies

Short notes
1. Brain abscess
2. Lacunar infarct (3)
3. Parkinsons disease
4. Treatment of parkinsons disease
5. Cauda equina and its lesions
6. CSF analysis in pyogenic meningitis
7. Meningococcal meningitis
8. Cryptococcal meningitis
9. CSF in cryptococcal meningitis
10. Hemiballismus
11. Classification of diabetic neuropathy
12. Thrombolysis in acute CVA
13. Diagnostic evaluation and management of suspected encephalitis
14. Evoked potentials
15. Charcot’s joint
16. Mitochondrial myopathies
17. Narcolepsy
18. Critical illness polyneuropathy
19. Pompe disease
20. EMG and its uses (2)
21. Fabry’s disease
22. Discuss myasthenia syndromes. Add a note on management
23. Congenital myasthenic syndromes
24. Spinal TB
25. Vertigo
26. Neoplastic meningitis
27. Temporal lobe epilepsy
28. Diagnostic criteria for multiple sclerosis (2)
29. Multiple sclerosis
30. Treatment of MS
31. Complications of TB meningitis
32. Lab diagnosis of TB meningitis
33. Restless leg syndrome (2)
34. Myotonic disorders
35. Circulation of CSF. Note on normal pressure hydrocephalus
36. NPH
37. Brain death (4)
38. Tuberous sclerosis
39. Cluster headache
40. HIE
41. Drug management in haemorrhagic stroke
42. Meningoencephalitis – treatment
43. Bromocriptine
44. Role of GABA analogues in epilepsy
45. Side effects of phenytoin
46. Anti-epileptics
47. Newer anti-epileptics
48. Recent drugs in parkinsonism
49. X-linked muscular dystrophies (2)
50. Duchenne muscular dystrophy
51. Myopathy
52. Subdural haematoma
53. Prion diseases (3)
54. Treatment of migraine
 55. Prophylaxis of migraine
56. Neuroprotective therapy in akinetic-rigid syndromes
57. Chorea
58. Athetosis (2)
59. Paradoxical stroke
60. Subacute combined degeneration of spinal cord
61. Japanese B encephalitis
62. Pathological features of Alzheimer’s disease (2)
63. Aetiopathogenesis and management of alzheimers disease
64. Diabetic autonomic neuropathy
65. Medical causes of voice disorders
66. Acute intermittent porphyria (2)
67. Usefulness of imaging modalities of the chest in the evaluation of gait ataxias
68. Internuclear ophthalmoplegia

Nephrology
Essay
1. Classify major causes of ARF. Discuss the pathophysiology, clinical features and management
of ATN (2)
2. Aetiopathogenesis, clinical features, management of ARF (2)
3. Define CKD. Aetiopathogenesis, clinical features, biochemical manifestations of CKD. Discuss
staging and management of CKD and add a note on complications. Indications for dialysis.
(4)
4. Acid-base disorders
5. Aetiology, clinical features, management of hyponatraemia
6. Causes, diagnosis, management of hypercalcaemia
7. Clinical features, diagnosis, staging, treatment of diabetic nephropathy (2)
8. Discuss the aetiopathogenesis, clinical features, management of glomerular diseases with
nephritis presentation
9. Histopathology of kidney – in health and disease

Short notes
1. Acute renal failure
2. RPGN (2)
3. Nephrotic syndrome
4. Renal manifestations of SLE (2)
5. Systemic manifestations of SLE
6. Microbes causing acute cystitis
7. Berger’s disease and IgA nephropathy
8. Gitelman’s syndrome
9. Anaemia in CRF
10. Treatment of acute uncomplicated UTI
11. Management of AKI in ICU
12. HIV associated nephropathy
13. Endogenous nephrotoxins and kidney injury
14. Liddle syndrome
15. Physiology of water balance
16. Hyponatraemia (4)
17. Abnormalities of potassium
18. Role of kidney in potassium homeostasis
19. Respiratory acidosis (2)
20. Respiratory alkalosis (2)
21. Lactic acidosis
22. Metabolic acidosis
23. Hypercalcaemia
24. AD-PKD
25. ABG
26. Pathogenesis of renal osteodystrophy
27. Renal osteodystrophy
28. Acute pyelonephritis
29. Aetiology of pyelonephritis
30. Metabolic alkalosis
31. Interstitial nephritis (2)
32. Renal transplantation (3)
33. Post-renal transplant management
34. Renal tubular acidosis (3)
35. Magnesium deficiency
36. Evaluation of haematuria
37. Haematological consequences of nephritic syndrome
38. Acute nephritic syndrome (2)
39. Donor nephrectomy
40. Problems with haemodialysis. Note on intermittent haemodialysis
41. Complications of dialysis
42. SIADH (3)
43. ECG and potassium – significance
44. Indications and contraindications of renal biopsy
45. Haemolytic uraemic syndrome
46. IgA nephropathy
47. Post-streptococcal glomerulonephritis – microscopic appearance
48. Anion gap
49. Renal failure indices
50. Pathology of membrane proliferative (mesangiocapillary) glomerulonephritis
51. Calcium metabolism (4)
52. Gittelmanns syndrome
53. Periodic paralysis syndrome
54. Renal failure with normal size or enlarged kidneys
 55. Adipsic hypernatraemia
56. Diabetes insipidus
57. Nephrogenic diabetes insipidus
58. Proteinuria
59. Causes and diagnosis of chronic renal failure
60. Alport syndrome

Endocrinology
Essay
1. Aetiology, pathogenesis, clinical features, diagnostic evaluation and treatment of
hypofunction of adrenal cortex
2. Discuss aetiology, evaluation and management of dwarfism
3. Pathogenesis, clinical features, lab diagnosis, management, complications of Grave’s disease
4. Define diabetes mellitus. Classify DM. Discuss the manifestations, diagnosis, treatment of
DKA
5. Describe the musculoskeletal manifestations of endocrine disorders
6. Aetiology, pathogenesis, clinical features, diagnostic evaluation, treatment of hypofunction
of adrenal cortex

Short notes
1. Type 1 DM (2)
2. Gestational diabetes
3. Lower limb complication of DM
4. Cutaneous markers of DM
5. Diabetic retinopathy (2)
6. Occult diabetes
7. Merits and de-merits of newer oral anti-diabetic drugs
8. OHA’s (2)
9. Newer OHA’s
10. Newer insulins (2)
11. Insulin degludec
12. Insulin analogues – clinical uses and benefits over human insulin (3)
13. DPP IV inhibitors – indications and clinical benefits
14. Emerging therapies in DM
15. Management of DKA (2)
16. Pagets disease (2)
17. Pancreatic transplantation
18. Male infertility
19. Hyperprolactinaemia
20. Carcinoid syndrome
21. Dawn phenomenon
 22. Werner’s syndrome
23. Diabesity
24. Osteoporosis (3)
25. Bone densitometry
26. Dwarfism
27. Short stature
28. Islet cell transplantation
29. POEMS syndrome
30. Delayed puberty (2)
31. Hirsutism
32. Vitamin D resistant osteomalacia
33. Metabolic syndrome
34. Autoimmune hypothyoroidism
35. Hyperinsulinaemia
36. TFT (4)
37. Hypothyroidism
38. Myxoedema coma
39. Thyroid storm – features and management
40. Thyroid dysfunction in pregnancy (2)
41. Graves disease

Psychiatry
Essay
1. Aetiology, pathophysiology, clinical features, management of depressive disorders
2. Approach to and management of patients with suicidal thoughts
3. Aetiology, clinical features, course, prognosis, management of panic disorders. Mention the
conditions that mimic panic disorder

Short notes
1. Mood disorders
2. Manic depressive psychosis / bipolar (5)
3. Manic depression (2)
4. Risk factors for suicide
5. Alcoholic hallucination
6. Approach to detoxification in alcohol dependence syndrome
7. Drug abuse
8. Eating disorders – classification, characteristics, treatment (2)
9. Effects of alcohol on CNS. Discuss alcohol withdrawal
10. Environmental and personal factors of parasuicide
11. OCD (5)
12. Management of OCD
 13. Somatoform disorder (2)
14. Somatisation disorder
15. Reactive depression (2)
16. Depression
17. Opioid abuse and dependence
18. Neuroleptic malignant syndrome (6)
19. Panic disorder (2)
20. Phobic disorder
21. Lithium uses and side effects
22. Lithium
23. Drugs causing anxiety
24. Catatonic schizophrenia and treatment
25. Schizophrenia (2)
26. Korsakoff’s psychosis and treatment (2)
27. PTSD (2)
28. Delirium
29. Acute delirium
30. Chronic fatigue syndrome (2)
31. Psychotherapy and psychological rehabilitation
32. Acute confusional state
33. Anorexia nervosa
34. Bulimia nervosa
35. SSRIs (2)
36. Delirium tremens
37. Hysterical conversion reaction

Paediatrics
Essay
1. Causes of seizures in children. Discuss aetiopathology, clinical features of complex partial
seizures
2. Causes, clinical features, lab diagnosis of metabolic acidosis in an infant
3. Describe protein energy malnutrition. Discuss classification, diagnostic criteria and
management. Note on ICDS programme (2)

Short notes
1. ADHD (3)
2. Breast feeding
3. Drugs and breast feeding
4. Downs syndrome
5. Kwashiorkor
6. Cretinism
 7. Congenital hypothyroidism
8. Febrile seizures (5)
9. Hyaline membrane disease (2)
10. Universal immunisation (4)
11. Marasmus (2)
12. Cerebral palsy (2)
13. Protein calorie malnutrition
14. Severe acute malnutrition (SAM) in children
15. Evaluation of haematuria in a child
16. Trinucleotide repeat disorders
17. Neuroblastoma
18. Paediatric advanced life support
19. Reye’s syndrome (2)
20. Metabolic disorders – neonatal screening
21. Infantile tremor syndrome
22. Dyslexia – causes and clinical features
23. Adolescent health problems and management
24. Diarrhoeal disease in children
25. Viral gastroenteritis in paediatrics
26. Evaluation of UTI in children
27. Obesity in children
28. Diagnosis and management of Wilm’s tumour
29. ITP in children
30. DKA in children
31. Pneumococcal vaccines
32. Growth and development milestones in a one-year-old infant
33. Evaluation of wheeze in a child
34. Knock knees in children
35. Hypovolaemic shock in paediatric age group
36. Management of worm infestation in children
37. Common skin ailment in school going children up to 10 years
38. Breath holding spell
39. Infantile diarrhoea
40. Congenital rubella syndrome

Toxicology
Essay
1. Name the commonest poisonous snakes of India. Discuss clinical features, management,
complications (2)
2. Clinical features, diagnosis, management of barbiturate poisoning
3. Clinical features, diagnosis, management of OPC (3)
 4. Enumerate common Childhood poisons. Clinical features, complications, management of
copper sulfate poisoning
5. Approach to acute poisoning and management

Short notes
1. Management of hanging
2. Scorpion sting and common species in India (5)
3. Mechanism of OPC, intermediate syndrome
4. Lead poisoning
5. Arsenic poisoning (2)
6. Near-drowning
7. How to obtain consent for intubation in a snake bite victim
8. Clinical features and management of viperine bite
9. Paracetamol poisoning
10. Digitoxicity treatment (2)
11. Methyl alcohol poisoning (2)
12. Barbiturate poisoning

Dermatology
Essay
1. Dermatological manifestations of infectious disease (2002)

Short note
1. Pemphigus vulgaris
2. Enumerate photosensitive dermatosis. Add a note on pellagra
3. Pellagra (2)
4. Scabies
5. Miliaria rubra
6. Steven-Johnson syndrome
7. Cutaneous drug reaction

Miscellaneous
Essay
1. Classify lipidosis. Discuss the aetiopathogenesis, clinical features and management of
Niemann pick disease
2. Discuss the various palliative medical care services in terminally ill patients
3. Enumerate clinical conditions requiring mechanical ventilation. Types of invasive and non-
invasive ventilator support. General considerations of management of ventilated patient
 4. Outline the haeme biosynthetic pathway and classify porphyrias. Discuss aetiology, clinical
features and management of AIP.

Short notes
1. Paraneoplastic visual syndrome
2. Paraneoplastic syndromes
3. Approach to diagnosis and management of an elderly patient presenting with acute delirium
4. Medical management of BPH
5. Histocompatibility typing and types of transplants
6. Acute radiation effects
7. Physiological effects of ageing
8. Care of the terminally ill
9. Enumerate illnesses of heat. Discuss Heat stroke (6)
10. Heat hyperpyrexia
11. Hypothermia
12. Thiamine deficiency
13. Scurvy
14. Tropical oral health and prevention of disease
15. Parenteral nutrition support
16. TPN
17. DD for low back ache
18. Radiation injury
19. SPECT
20. Swan-Ganz catheter
21. Tissue engineering
22. Familial Mediterranean fever
23. Lysosomal storage diseases
24. Klinefelter’s syndrome (2)
25. Dual energy X-ray scan
26. Role of trace elements in nutrition and health
27. Fluorosis
28. Obesity
29. Spiral CT
30. Types and usefulness of tissue engineering
31. Concepts and components of hospice care
32. Management of chronic pain
33. Euthanasia
34. CPAP
35. Heart-lung transplant
36. Chief – ECMO
37. Neuropsychiatric manifestations of vitamin deficiency
38. Anthropometrics
39. Pneumatic antishock garment (PASG)
40. Mediastinitis
 41. Epidemic dropsy (3)
42. Beri beri
43. Brain death

Infectious diseases
Essay
1. Neurological diseases in HIV (2)
2. Principles of HAART and classification of ART drugs. Explain who to initiate HAART in an ART-
naïve individual, complications of treatment and how to monitor
3. Evaluation and management of pulmonary infections in HIV
4. Diagnosis, lab investigations, management of AIDS. Enumerate the opportunistic infections
and management of these infections in a case of HIV (2)
5. Discuss in detail the organ specific syndromes associated with HIV infection

6. Enumerate the various parasites that affect the liver and describe the lifecycle and
management of any one in detail
7. Describe the pulmonary manifestations of parasitic infections in the tropics
8. Enumerate the zoonoses in the tropics. Outline the neurological manifestations of each
9. Describe the haematological manifestations of infectious disease
10. Neurocysticercosis – aetiopathogenesis, clinical features, management
11. List the major viral haemorrhagic fevers. Describe the clinical manifestations, complications
and management of viral haemorrhagic fevers
12. Classify dengue fever and discuss the clinical features and management of severe dengue in
a child (2)
13. Classify leptospirosis. Given an account of management and complications.
14. Life cycle of plasmodium falciparum. Clinical features and management (8)
15. Outline the emergencies encountered in parasitic infestations, and describe in detail the
clinical features and management of black water fever
16. Enumerate the various protozoa that affect the intestine and describe the life cycle, clinical
features and management of any one in detail
17. Name blood flukes. Discuss the life cycle, clinical features and management of any one in
detail
18. Aetiology, evaluation and management of 30 year old patient with fever and skin rashes of 5
days duration
19. Discuss aetiology, pathophysiology, clinical features, management of cestodes
20. Approach to a patient with fever and an eschar and management
21. Aetiopathogenesis, clinical features, management of Rickettsial disease
22. Epidemiology, aetiopathogenesis, clinical features, lab diagnosis, treatment, complications
of typhoid fever
23. Aetiopathogenesis, clinical features, complications, management of salmonellosis
24. Aetiology, pathogenesis, clinical features, treatment of cholera
 25. Epidemiology, aetiopathogenesis, clinical features, lab diagnosis, treatment, complications
of lymphatic filariasis (3)
26. Life cycle, pathology, clinical features and management of Wuchererira Bancrofti
27. FUO – classify, approach to diagnosis, management
28. Infectious mononucleosis – aetiology, pathophysiology, clinical features, diagnosis,
management, complications
29. Toxoplasmosis – aetiopathogenesis, clinical features, investigation, management (2)
30. Classify leprosy. Clinical features, diagnosis, management of lepromatous leprosy.
Reactional states in leprosy and their management
31. Various infection caused by mammalian bites and discuss in detail the management of
dogbite
32. Brucellosis – immunity, pathogenesis, clinical features, diagnosis, treatment, prognosis,
follow-up and prevention

Short notes
Bacteria
1. Syphilis
2. Neurosyphilis
3. Gonococcal infection
4. Leprosy
5. Paucibacillary leprosy – diagnosis and treatment
6. Cultivation of M. leprae
7. Lepra reaction (3)
8. Mycoplasma
9. Mycoplasma pneumoniae
10. Leptospirosis, note on Weils disease (9)
11. Lab diagnosis of leptospirosis (5)
12. Management of leptospirosis
13. Treatment of typhoid
14. Non-typhoidal salmonellosis (2)
15. MDR salmonellae
16. Botulism (2)
17. Lymphogranuloma venereum
18. Salmonellosis. Note on MDR enteric fever
19. Shigellosis
20. Classify opportunistic mycobacteria and the disease in humans
21. Nontuberculous mycobacteria (NTM)
22. Atypical mycobacterial infections (2)
23. MRSA management
24. MSSA management
25. Scrub typhus
26. Louse-borne relapsing fever
 27. Buruli ulcer
28. HEAF test
29. Diphtheria (2)
30. Whooping cough
31. Legionnaire’s disease (3)
32. Pseudmembranous colitis
33. Brucellosis (4)
34. Typhus fevers
35. Febrile neutropaenia (2)
36. Wool sorters disease
37. Oral typhoid vaccine
38. Plague (2)
39. Malignant pustule
40. Anthrax (2)
41. Tropical ulcer
42. Cholera sicca
43. Tetanus
44. Ulceroglandular fever
45. Bacillary angiomatosis
46. Trachoma
47. Gonorrhoea
48. Lyme disease
49. Tick paralysis
50. Melioidosis
51. Water house – Friderichsen syndrome

Viruses
1. Chikungunya fever (3)
2. HSV (2)
3. Herpes zoster (2)
4. Clinical features and management of dengue
5. Dengue fever
6. Active and passive immunisation in rabies (2)
7. Lab diagnosis of rabies
8. Rabies (2)
9. Dumb rabies
10. H1N1 infection
11. Chickenpox
12. JE – epidemiology and management (2)
13. Lab diagnosis of AIDS
14. Serological diagnosis of HIV infection
15. Acute HIV seroconversion illness
16. AIDS dementia complex
17. CD4 count and HIV associated disease (2)
 18. Ocular manifestations of opportunistic infections in AIDS
19. Genetic factors implicated in pathogenesis of HIV
20. HAART (4)
21. Side effects of ART drugs, note on HAART
22. Newer ART drugs
23. Window period
24. Infectious mononucleosis – diagnosis complications and management (3)
25. Recent outbreaks with various influenza viruses. Note on H5N1 influenza
26. Influenza vaccine
27. Swine flu management
28. Oral hairy leukoplakia
29. Management of nocardiosis
30. Serological tests for syphilis
31. Tropical (pulmonary) eosinophilia (5)
32. CMV infection
33. Yellow fever
34. Epidemic myalgia
35. Diagnosis and management of CMV retinitis
36. Ebola virus
37. Polio prevention programme (2002)
38. Poliomyelitis (2008)
39. Human diploid cell vaccine
40. Subacute sclerosing pan encephalitis (2)
41. Prevention of hepatitis B and HIV in health care workers
42. Hanta virus
43. SARS
44. Extra-hepatic complications of hepatitis B
45. EBV infections
46. Kyasanur forest disease
47. Spectrum of arboviral infections in india
48. Measles
49. Complications of measles
50. HPV
51. Mumps
52. Hairy leukoplakia

Protozoa
1. Leishmaniasis (2)
2. Visceral leishmaniasis (3)
3. Recent advances in management of Kala azar
4. Chiclero ulcer
5. Filariasis
6. Amoebiasis
7. Extra-intestinal amoebiasis (2)
 8. Amoebic liver abscess (3)
9. Amoebic encephalitis
10. Hydatid cyst
11. Bilharziasis
12. Cysticercosis
13. Neurocysticercosis and indications to treat (2)
14. Tropical splenomegaly syndrome (5)
15. Complications of falciparum malaria (2)
16. Pernicious malaria
17. Treatment of chloroquine-resistant falciparum malaria
18. Artemisinin combination therapy in resistant malaria
19. Newer drugs in malaria
20. Quartan malaria
21. Visceral larva migrans
22. Cutaneous larva migrans
23. Clinical features and management of cutaneous larva migrans
24. Larva currens
25. Non-filarial elephantiasis
26. Podoconiosis – clinical features and management
27. Classify intestinal protozoal infections. Outline life cycle of Giardia
28. Giardiasis (3)
29. What are ectoparasitic infestations. Discuss their relevance in HIV/AIDS
30. Onchocerciasis
31. Isospora belli
32. Life cycle of ankylostoma duodenale
33. Round worm
34. Hook worm (2)
35. Toxoplasmosis complications
36. Cerebral toxoplasmosis – diagnosis and management
37. Toxoplasmosis (2)
38. Diagnosis and management of African trypanosomiasis
39. Life cycle of pin worms
40. Lab diagnosis of lung parasites
41. Malaria vaccine
42. MMR vaccine
43. Coxiella burnetii
44. Ascariasis
45. Microbiological diagnosis of malaria
46. Serological and molecular tests for parasitic infestations
47. Balantidiasis
48. Guinea worm

Fungal
1. Superficial mycosis
 2. Management of mucocutaneous candidiasis
3. Candidiasis (2)
4. Mycetoma foot/Madura foot (2)
5. Actinomycosis
6. Lab tests for Cryptococcus (2)
7. Cryptococcal infections (2)
8. Mucormycosis (2)
9. Histoplasmosis
10. Systemic fungal infection

Miscellaneous
1. Toxic shock syndrome (3)
2. Septic shock (2)
3. Kuru (2)
4. SSS Syndrome
5. Toxic shock syndrome – clinical features and management
6. Enumerate the infectious diseases associated with polyserositis. Note on familial
Mediterranean fever
7. Hyperthermia
8. Infectious oesophagitis
9. Adult vaccination (2)
10. Septic encephalopathy
11. Pyrexia of unknown origin
12. Nosocomial infection
13. Infection control in hospital
14. Tropical pyomyositis