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The document outlines key concepts related to T cell receptors (TCR) and their activation, including the components of TCR, the interaction with MHC molecules, and the signals required for T cell activation. It emphasizes the importance of TCR development in the thymus and the role of cytokines produced by antigen-presenting cells (APCs). Additionally, it highlights the functions of different T cell types in response to intracellular bacteria and infected macrophages.

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Qudamah Jasem
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6 views2 pages

BT Template

The document outlines key concepts related to T cell receptors (TCR) and their activation, including the components of TCR, the interaction with MHC molecules, and the signals required for T cell activation. It emphasizes the importance of TCR development in the thymus and the role of cytokines produced by antigen-presenting cells (APCs). Additionally, it highlights the functions of different T cell types in response to intracellular bacteria and infected macrophages.

Uploaded by

Qudamah Jasem
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Lecture10

1-T Cell receptor is a Membrane bound:

A- Glycoprotein
B- Glucosamine
C- Peptidoglycan

Ans:A

2- The TCR plus CD3 =

A- CD complex
B- TCR complex
C- Cd3 complex

Ans:B

3- TCR on T cytotoxic (CD8) cells recognize antigen with:

A- MHC1
B- MHC2
C- MHC3

Ans:A

4- After the T cell enters the thymus, it starts developing theT cell receptor (TCR) by a process
known:

A- Phenotype
B- Gene expression
C- Gene rearrangement

Ans:c

5- T cell that interacts strongly with self antigen will :

A- Be removed
B- Receive signal of survival
C- Maintained

Ans:A
6- T cell activation require 3 signals, the first is:

A- delivered by cytokines
B- B7 on the APC binding to CD28 on the T cell
C- The TCR binding to MHC plus (foreign) peptide

Ans:C

7- The cytokines in T cell activation produced by:

A- APC
B- T Cell
C- Adenoid

Ans:A

8- intracellular bacteria are target for :

A- TH 1
B- TH 2
C- CD 8

Ans:C

9: infected macrophages are activated by:

A- CD 8
B- TH 1
C- TH2

Ans:B

10- Has antimicrobial action and can induce apoptosis :

A- Granulysin
B- Fas ligand
C- Granzymes

Ans:a

Written by:Noura Alenzi

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