UHPLC Pump 770

Service Manual

0060.368-15
March 2023
0060.368-15 UHPLC Pump 770 Service Manual

Original instructions

Copyright ©2023 All rights reserved. No part of this publication may be reproduced, stored in a
retrieval system or transmitted in any form by any means, without written permission from the
manufacturer.
The manufacturer reserves the right to make changes to the design and specifications of the
system and this manual without prior notice.

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0060.368-15 UHPLC Pump 770 Service Manual

Contents

1. About this manual 5

1.1 Pictorials 5
1.2 Safety instructions 6

2. Identification of Parts 10
2.1 Instrument - front 10
2.2 Instrument - rear 11

3. Control software 12
3.1 Service Menu 12
3.1.1 Flow settings 13
3.1.2 Pressure 14
3.1.3 Pressure graph 14
3.1.4 I/O control and settings 15
3.1.5 Log counters 15
3.1.6 Production 16
3.1.7 Wizards and tests 16

4. Maintenance 18
4.1 Piston and seal replacement 18
4.2 Calibration wizard 19
4.3 Spindle lubrication 19
4.4 Check valve replacement 20
4.5 Purge valve replacement 21

5. Troubleshooting 23
5.1 Diagnostics 23
5.2 Pressure screen 23
5.3 Dynamic leak test 25

6. Disassembly 27
6.1 Removing the top cover 27
6.2 Access to support pumps and degasser 27
6.3 Replacing the purge valve drive, vacuum chamber, selection valve 29
6.4 Main board replacement 29
6.5 Removing the power supply 30
6.6 Replacing a pump drive 31
6.7 Replacing the power supply 34

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7. Performance inspection 35
7.1 System setup 35
7.2 Flow accuracy 35

Appendix A. Spares and Accessories 36

A.1 Spare parts 38
A.2 Standard PM kit - Part # 0770.772 42
A.3 Premium PM kit - Part # 0770.764 43
A.4 Basic PM kit - Part # 0770.765 43

Appendix B. Error Codes 45

Appendix C. Storage, packaging, recycling and disposal 50

Appendix D. PCB layout 52

Appendix E. Exploded views 53

Index 62

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0060.368-15 UHPLC Pump 770 Service Manual

1. About this manual

This service manual is intended for trained and qualified service engineers who
perform service on the pump.
Refer to the user manual for information on the standard operating procedures.

1.1 Pictorials

The following pictorials may occur in this manual:

This sign warns about the risk of electrical shock. It calls attention
to a procedure or practice which, if not adhered to, could result in
electrocution.
Do not proceed beyond this danger sign until the indicated
conditions are fully understood and met.
The warning sign denotes a hazard. It calls attention to a
procedure or practice which, if not adhered to, could result in
severe injury, loss of life or damage or destruction of parts or all of
the equipment.
Do not proceed beyond a warning sign until the indicated
conditions are fully understood and met.
The caution sign denotes a hazard. It calls attention to a
procedure or practice which, if not adhered to, could result in
damage or destruction of parts or all of the equipment.
Do not proceed beyond a cautions sign until the indicated
conditions are fully understood and met.
The fire hazard sign draws attention to the fact that use of
flammable solvents or samples may cause a significant safety
risk.
The toxic hazard sign draws attention to the fact that use of toxic
solvents or samples may carry a significant health risk.

The biohazard sign draws attention to the fact that use of

biological materials, viral samples and needles may carry a
significant health risk.
The hot surface sign calls attention to parts in the instrument that
must not be touched, as they may cause burns

The optical radiation sign warns about possible eye injury due to
hazardous optical radiation.

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0060.368-15 UHPLC Pump 770 Service Manual

The ESD Safety sign warns about damage to sensitive electronic

components due to electrostatic discharge.

The attention sign signals relevant information. Read this

information, as it might be helpful.

The note sign signals additional information, providing advice or a

suggestion that may support you in using the equipment.

This symbol indicates that the waste of electrical and electronic

equipment must not be disposed as unsorted municipal waste
and must be collected separately. Please contact an authorized
representative of the manufacturer for information concerning the
decommissioning of equipment.

1.2 Safety instructions

Adhere to standard quality control procedures and the following equipment

guidelines when using the system:

General safety
The system working environment should meet the specifications
indicated in this manual.
The system is intended to be used in a regulated laboratory
environment with trained operators following good laboratory
practices.
Use this system ONLY for its intended use. Use of the system for
any other purpose may cause unsafe situations.
Do not use the system if there is any visible damage.
The system working environment should meet the specifications
indicated in this manual.
System operation and maintenance
To keep up the specified performance of the system,
maintenance must be carried out as indicated in this manual.
Service contracts and preventive maintenance services are
available. Please contact your local dealer or the nearest sales
office for more information.
Electrical safety
The system must be connected to a suitable mains power supply
with a correctly installed protective earth conductor. Never use
the system without a properly connected protective earth
conductor.
Read the installation instructions before connecting the system to
the mains power supply.

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0060.368-15 UHPLC Pump 770 Service Manual

Removal of panels may expose users to lethal voltages. For that

reason, this should only be done by qualified service engineers.
Disconnect the system from the all power sources before
removing protective panels.
Replace or repair faulty insulation on power cords immediately.
Solvents
The solvents used may be flammable. The room in which the
system is installed should be well ventilated to prevent that
solvent vapors cause a fire.
Do not allow solvents to accumulate in the system.
Perform periodic leak checks on fluid lines.
Solvent handling
When handling solvents always observe good laboratory
practices. Know the properties of the solvents used. This
information can be found in Material Safety Data Sheets (MSDS)
supplied by the vendor.
Avoid the use of the following solvents when using a steel
containing flow path:

l Solvents containing strong complexing agents like EDTA.

l Strongly acidic mobile phases (pH <1).

l Halogenated solvents or additives that form radicals and/or

acids.

l Solvents able to form peroxides like chromatographic grade

ether and non-stabilized THF, dioxane and diisopropyl
ether. In case use of these solvents is unavoidable, they
need to be filtered through dried aluminum oxide in order to
remove the peroxides.
Toxic Hazard
When you use or analyze toxic fluids you need to take all possible
precautions and treat all specimens as potentially toxic.
Leaking solvent connections can cause vapor accumulation in the
oven compartment. These vapors can be toxic. Make sure you do
not breathe in vapors while opening the oven door.
Always wear protective goggles and gloves when handling toxic
samples.
Biological Hazard
When you analyze biological fluids, you need to take all possible
precautions and treat all specimens as potentially infectious.
Always wear protective goggles and gloves when handling toxic
or biologically infectious samples.

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0060.368-15 UHPLC Pump 770 Service Manual

Waste disposal
Dispose of waste (samples, solvents, device) in accordance with
a regulated waste disposal program. Follow a regulated,
approved waste disposal program and never dispose of solvents
through the municipal sewage system.
Electrostatic Discharge (ESD)
Use a personal grounding device or wrist strap. This device or
wrist strap must always be worn snugly to assure skin contact at
all times. It must be connected to a common point ground to drain
static charges present on the body.
Applications: quality control
It is recommended that you routinely run several quality control
samples.
Quality control samples should represent low, average and high
levels of a compound. Make sure that quality control sample
results are within an acceptable range, and evaluate precision
from day to day and run to run.
Data collected when quality control samples are out of range may
not be valid. Do not report this data until you are certain that
system performance is acceptable.
Apart from use of quality control samples, we recommend that
you use blanks. The blanks will help you assess whether carry-
over is within an acceptable range, and they will help you in
monitoring the integrity of your data.
It is also recommended that you use a proper internal standard.
If the system runs into an error state, the results for the processed
sample should not be trusted.
EMC caution statement
This device complies with the emission and immunity
requirements described in the IEC61326 standard.
Do not use this device in close proximity to sources of strong
electromagnetic radiation (e.g. unshielded intentional radiators),
as these can interfere with proper operation.
If this device is integrated into a system, the user is responsible
for electromagnetic compatibility of the overall system.
FCC emission notice
This device complies with Part 15 of the FCC Rules. Operation is
subject to the following two conditions: (1) this device may not
cause harmful interference, and (2) this device must accept any
interference received, including interference that may cause
undesired operation.
However, there is no guarantee that interference will not occur in
a particular installation.

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0060.368-15 UHPLC Pump 770 Service Manual

Changes or modifications not expressly approved by the party

responsible for compliance, could void the user’s authority to
operate the equipment. Only use this device with the specified
cables.
Canada spectrum management emissions notice
This class A digital product apparatus complies with Canadian
ICES-001.
Cet appareil numérique de la classe A est conforme à la norme
NMB-001.
ISM Classification
This device has been classified as ISM Group 1 Class B in
accordance with IEC CISPR 11 Industrial Scientific and Medical
(ISM) instruments requirements.
Class B products are suitable for use in both commercial and
residential locations and can be directly connected to a low
voltage, power-supply network.
Korean EMC notice
This device complies with MSIP (Ministry Of Science, ICT, and
Future Planning) EMC registration requirements. This instrument
is registered as a Class B instrument for residential and/or
business use.
B급 기기 (가정용 방송통신기자재) 이 기기는 가정용(B급) 전자파
적합기기로서 주 로 가정에서 사용하는 것을 목적으로 하며, 모든
지역에서 사용할 수 있습니다.

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0060.368-15 UHPLC Pump 770 Service Manual

2. Identification of Parts

Use this section to find the location of parts.

2.1 Instrument - front

Figure 1: Front view

1. Solvent selection valve, degasser, seal wash inlet

2. Purge valve

3. Outlet filter

4. Mixer 35 µL (100 µL optional)

5. Purge/prime block

6. Status LED / Power switch

7. Primary pump head pump B

8. Secondary pump head pump B

9. Secondary pump head pump A

10. Primary pump head pump A

11. Leakage drain outlet

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0060.368-15 UHPLC Pump 770 Service Manual

2.2 Instrument - rear

Figure 2: Rear view

1. Ethernet connector

2. USB connector

3. RS 232 Multilink

4. Input/output

5. Mains inlet, fuses and power switch

6. Ventilation (do not obstruct) Make sure there is at least 100 mm free
space behind the pump.

The manufacturer will not accept any liability for damages directly
or indirectly caused by connecting the instruments in the system
to instruments which do not meet relevant safety standards.

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0060.368-15 UHPLC Pump 770 Service Manual

3. Control software

The instrument is controlled by ServiceLink control software.

Refer to the User manual for information on software installation, instrument
configuration and general use.

3.1 Service Menu

1. Open ServiceLink.

2. Select the Direct Control tab and select the arrow next to the instrument
to open the popup menu.

Figure 3: Service menu

3. Select the Service menu option.

Figure 4: ServiceLink – Service code login

4. Enter service code: 101163 and select OK.

5. The Flow settings window opens:

Figure 5: Flow settings

The left-hand side offers several options; for each option a separate window is
available. The following chapters explain the available functions per page.

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0060.368-15 UHPLC Pump 770 Service Manual

Switching the purge valve manually while the system is under

pressure might damage the column. It is strongly advised to
ensure the entire system is at ambient pressure before switching
the purge valve.

3.1.1 Flow settings

Figure 6: Service - Flow settings

This window allows you to control:

l Flow setting

l Maximum/minimum pressure setting.

Whenever the pressure is outside this window during operation an error
will appear.

l Solvent selection, purge valve position. Do not activate the valve while
the pump is running.

l Prime and purge control, for automatic priming and purging.

l Degasser and seal wash.

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0060.368-15 UHPLC Pump 770 Service Manual

3.1.2 Pressure

Figure 7: Service - Pressure

This page provides detailed information on each pressure sensor during the
run.
Please refer to section 6.1 of the user manual for a complete description.
The “zero pressure” is used to zero the pressure sensors, should be activated
whenever work has been done on the pump heads.

3.1.3 Pressure graph

Figure 8: Service - Pressure graph

This page provides information on the system pressure.

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0060.368-15 UHPLC Pump 770 Service Manual

3.1.4 I/O control and settings

Figure 9: Service - I/O

Please refer to the user manual for detailed information.

3.1.5 Log counters

Figure 10: Service - Log counters

This page provides information on usage, and allows you to reset the log
counters.

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3.1.6 Production

Figure 11: Service - Production

Firmware upload
1. Click to browse to the location of the

flash file

2. Click .

The new firmware is uploaded.

PCB Programming Allows you to enter the part number of the PCB.
Serial number Allows you to enter the serial number of the pump
Max. pressure (Bar) Allows you to set the maximum pressure
Fans Shows the current RPM of the fans
Pressure sensors These values are set during the zero and calibration
wizard. Not manual programmable.

3.1.7 Wizards and tests

Figure 12: Service - Wizards and tests

Dynamic leak test To start the leak test (See "Dynamic leak test" on

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0060.368-15 UHPLC Pump 770 Service Manual

page 25
Pump head Wizard to start the pump head replacement and
maintenance maintenance.
Follow the instructions given during the wizard.
Calibration wizard Wizard to calibrate the pressure sensors.
Follow the instructions given during the wizard.
Lubrication wizard Wizard to start the spindle lubrication (see "Spindle
lubrication" on page 19).
Follow the instructions given during the wizard.
Tests LED test.

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0060.368-15 UHPLC Pump 770 Service Manual

4. Maintenance

The pump is designed for many years of trouble-free operation. To keep the
pump in optimal condition, preventive maintenance is required after 12 months
of use, or after 120 liters have passed through the system, whichever comes
first. Preventive maintenance must be performed by an authorized service
engineer.
During a PM wetted parts are replaced and the drives will be lubricated.
l Parts inside the pump head are extremely sensitive to dirt
and dust particles.

l It is strongly advised to proceed with the next steps in a

clean environment.

l Before you start any work on the pump heads, place the
solvent bottles at a lower level than the pumps, to prevent
solvent from flowing from the open ends.

l In order to avoid any damage to the piston and or seals it is

required to set the pump heads in the exchange position.

l Do NOT switch off the pump during maintenance.

Available parts for the PM (see " Spares and Accessories" on page 36):

l 0770.765 - Basic PM kit

l 0770.772 - Standard PM kit

l 0770.764 - Premium PM kit

Tools:

l 0770.710 - Toolkit

l Lint free tissues

l Isopropanol

4.1 Piston and seal replacement

In the service screen there is a wizard that will act as a guide through the seal
and piston replacement procedure.

For piston and seal replacement it is required to use this wizard.

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0060.368-15 UHPLC Pump 770 Service Manual

Start the Pump head maintenance wizard in the service screen and follow the
instructions.

Figure 13: Wizard - Pump head maintenance

4.2 Calibration wizard

Each pump head is equipped with a pressure sensor. These sensors need to
be calibrated to create a well performing pump.

Whenever pump heads are replaced or moved from location (e.g.

A to B), it is required to calibrate the pressure sensors. Run the
calibration wizard, to perform this calibration.

To execute the Calibration wizard, use water as mobile phase.

1. Make sure the pump has been primed and purged.

2. Open ServiceLink Maintenance > .

3. Select Calibration wizard .

4. Follow the steps in the wizard.

5. After successful calibration select Finish.

4.3 Spindle lubrication

In order to keep the spindles in good condition it is required to lubricate them

every year or after 120 Liters, whichever comes first.
To perform lubrication, a special greasing kit and a software wizard have been
developed.
Only use the grease supplied by the manufacturer.
Start the Lubrication wizard in the service screen and follow the instructions.

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0060.368-15 UHPLC Pump 770 Service Manual

Figure 14: Wizard - Lubrication

4.4 Check valve replacement

The pump has 4 check valves in total. Each pump has 1 inlet and 1 outlet valve.
Each check valve contains the same type of cartridge. For convenience the
cartridges are provided with an arrow. These should always point upwards.
Always tighten check valve housings with 8Nm torque:

l When housings have been loosened or removed.

l When leakage occurs from check valve housings.

Required tools:

l Open wrench ½”

l Open wrench ¼ “

l Torque wrench with ½ “socket

1. For the outlet check valve

remove the tubing between
the two pump heads.

2. For the inlet check valve

remove the inlet tubing.

Figure 15: Pump heads

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0060.368-15 UHPLC Pump 770 Service Manual

3. Use the ½ “open wrench to

unscrew the check valve.

Figure 16: Unscrew check valve

Figure 17: Check valve housing and

cartridge
4. Install the new cartridge with the arrow pointing upwards.
For the inlet as well as for the outlet.
5. Tighten the cartridge with the torque wrench to 8 Nm.

4.5 Purge valve replacement

Required tools:

l ¼” open wrench

l Philips screw driver #2

1. Remove the tubing from the

valve.

2. Loosen the 2 Philips screws.

3. Slide the valve out of the drive.

Figure 18: Loosen the 2 marked Philips

screws

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0060.368-15 UHPLC Pump 770 Service Manual

4. Place the mounting plate on

the new valve.

5. Before installing the new valve

in the pump, please make
sure the pin in the drive shaft
is in the horizontal position, as
shown in the picture on the
Figure 19: Front view (left) and rear view
right. (right)

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5. Troubleshooting

Refer to the User manual for troubleshooting procedures.

5.1 Diagnostics

This section describes information that will help in diagnosing malfunctioning.

In the text below only, the A pump is shown, the same information counts for
the B pump as well.
The green bar represents the pressure in the primary pump head.
The blue bar represents the pressure in the secondary pump head.

5.2 Pressure screen

The screens below will give information that helps in diagnose any
malfunctioning.

Pump runs according to specifications

Figure 20: Pressure - according to specifications

l Pressure in the primary pump head (green bar) will increase until 6 Bar
below the secondary pump head (blue bar)

l During refill stroke pressure in primary head will drop and secondary
pressure will remain stable.

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0060.368-15 UHPLC Pump 770 Service Manual

Pressure pulsating – Flow incorrect

Figure 21: Pressure – incorrect flow

Top:
Blue bar: Fluctuating
Green bar: No pressure buildup
Bottom:
Blue bar: Fluctuating
Green bar: Fluctuating

Error 778 will pop up:

Possible causes:

l Air in pump head A. Prime/Purge pump to resolve this.

l Inlet check valve is not closing.

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0060.368-15 UHPLC Pump 770 Service Manual

Flow unstable

Figure 22: Pressure - unstable flow

Pressure in all pump heads fluctuate.
No difference in pressure between primary, secondary A and secondary B
Pressure on primary B is 6 bar below secondary B
Possible cause:

l Outlet check valve pump A is leaking.

5.3 Dynamic leak test

Purpose of the dynamic leak test:

Check for leakage. This test provides information if there is any leakage at the
seals or outlet check valve.

Before starting the test, make sure the pump is primed and purged.
Start the wizard and follow the instructions.

Figure 23: Wizard - Dynamic leak test

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0060.368-15 UHPLC Pump 770 Service Manual

Figure 24: Leak test results

Results within -5 and + 5 can be considered satisfactory.

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6. Disassembly

This section describes how to get access to the inner parts of the instrument.

Unplug the instrument before accessing the inside!

The pump contains electrostatic sensitive parts. Use proper

grounding techniques to prevent damage to the instrument.

Required tools:

l Philips screw driver # 1

l Philips screw driver # 2

l Flat screw driver.

l ¼”” open wrench

6.1 Removing the top cover

1. Remove 2 screws on the rear

side and 1 on the front.

2. Remove the 4 tubing guides.

3. Use a small flat head

screwdriver to lift part A.

4. Then slide the guide (B) to the

front.

5. Lift the top cover.

6.2 Access to support pumps and degasser

To gain access to support pumps and degasser, lift the top foam section:

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0060.368-15 UHPLC Pump 770 Service Manual

Figure 25: Lift the top foam section

1. Purge valve drive

2. Solvent selection valve

3. Vacuum chamber

4. Seal wash pump

5. Main board

6. Purge pump

7. Degasser

To replace the degasser, purge pump and the seal wash pump, no other tools
are required. Simply lift each part from the foam and disconnect the
corresponding connector and tubing.

If any of the tubing inside the pump are reconnected or replaced it

is strongly advised to prime and purge the pump before installing
the upper foam part. This will allow you to check for leakage.

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0060.368-15 UHPLC Pump 770 Service Manual

6.3 Replacing the purge valve drive, vacuum chamber, selection valve

To replace the valve drive (2) or vacuum chamber/selection valve (1):

1. Remove all tubing connected to these parts.

2. Slide the foam to the rear as indicated below. There is now enough
space to lift the assemblies.

Figure 26: Replacing purge valve drive, vacuum chamber, selection valve

6.4 Main board replacement

The main board contains electrostatic sensitive parts. Use proper

grounding techniques to prevent damage to the instrument.

l Disconnect the wiring.

l Remove the 4 plastic screws and the 4 screw locks on the rear:

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Figure 27: Main board replacement

After replacing the main board, it is required to run the calibration

wizard. Since calibration values are stored in the non-volatile
memory of the board.
See " Wizards and tests" on page 16

Figure 28: Wizard - Calibration

6.5 Removing the power supply

To get access to the power supply, disconnect the mains power line.

1. Remove the main board (see "Main board replacement" on the previous
page).

2. Lift the top foam section.

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0060.368-15 UHPLC Pump 770 Service Manual

3. Disconnect the cables from the power supply.

Figure 29: Lift the top foam section

4. Remove the power supply.

6.6 Replacing a pump drive

To replace a pump drive:

1. Remove the top cover (see "Removing the top cover" on page 27).

2. Lift the top foam section.

Figure 30: Lift the top foam section

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3. Remove all the tubing from the front panel:

Figure 31: Remove tubing

4. Remove only the pump head from the drive that must be replaced:

Figure 32: Remove pump head

Please note that the back of the pump head contains a very
strong magnet. Make sure no metal parts or debris come close to
the magnet:

Figure 33: Magnet in pump head

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5. Disconnect the prime tubing from the frontpanel.

Figure 34: Disconnect prime tubing

6. Lift the foam section including peripherals from the cabinet. There is no
need to disconnect any wiring. Be careful not to damage the flex PCB.

Figure 35: Move the foam section

7. Move the foam section with peripherals to the side.

8. Disconnect the wiring from the drive you need to replace.

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0060.368-15 UHPLC Pump 770 Service Manual

9. Lift the drive from the lower foam section.

Figure 36: Lift drive from foam section

10. Reassemble in the opposite order.

11. Tighten pump head hex screws to 8Nm using a torque wrench.

Check for leakage: after installing the drive and the internal and
external tubing, prime the pump before placing the top foam.

6.7 Replacing the power supply

To get access to the power supply, remove the main board (see "Main board
replacement" on page 29) and lift the foam part.

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7. Performance inspection

Below are instructions how to check the performance of the pump after repair
or maintenance. Required tools:

l Water (UHPLC grade)

l Flow meter

7.1 System setup

Figure 37: System setup for performance inspection

l A1 H2O (UHPLC grade)

l B1 H2O (UHPLC Grade)

l Column: to create backpressure, approx. 600 bar (8,000 psi) at 1,000

µL/min

l Flow meter (for example V-Kit)

7.2 Flow accuracy

1. Set up the system as indicated in the above configuration.

2. Open Direct control in ServiceLink.

3. Make sure the pump has been primed and purged.

4. Do the experiment using the flowrate and backpressure settings

described in the table below.

5. Make sure the pressure is stable for 5 minutes. Record the flowrate for 1
minute at 10 measurements per second.

6. Check pressure graph for monitoring pressure.

Flow (µL/min) Backpressure Specification flowrate

200 ± 100 bar (1,400 psi) 190 – 210 µL/min
1000 ± 600 bar (8,000 psi) 990 – 1010 µL/min

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Appendix A. Spares and Accessories

This section lists spare parts available for the pump.

To ensure correct functioning of the pump, use the original tubing

from the manufacturer. If any other type of tubing is used, this will
influence performance negatively.

High pressure tubing pre-bended

Figure 38: High pressure tubing

1. 0770.741 High pressure tubing 1/16” (pump to pump)
2. 0770.744 Stainless steel tubing 1/16” (valve to mixer)
3. 0770.746 Stainless steel tubing 1/16” (valve to purge pump)
4. 0770.745 Stainless steel tubing 1/16” (valve to purge pump)
5. 0770.742 High pressure tubing 1/16” (pump A to valve)
6. 0770.743 High pressure tubing 1/16” (pump B to valve)

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0060.368-15 UHPLC Pump 770 Service Manual

Low pressure tubing

Figure 39: Low pressure tubing

0770.757 Low pressure tubing set; consists of:

1. Pump tubing

2. Seal wash tubing

3. Nuts and ferrules

Internal tubing

Figure 40: Internal tubing

1. 0770.750 ETFE Tubing 1/16” – OD 1mm ID
2. 0770.747 Tubing Silicon 7 mm – OD 3 mm ID

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A.1 Spare parts

Part Description
number
0770.724 Pump head primary

0770.725 Pump head secondary

0770.737 High pressure seal

0770.702 Piston/cartridge
replacement

0770.703 Seal replacement tool

0770.704 Front head primary

0770.705 Front head assy

secondary

0770.712 Lubrication kit

Includes:
Lubrication
tool, 4
syringes
with grease.

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Part Description
number
0770.729 Check valve housing
outlet

0770.728 Check valve housing

inlet single

0770.738 Check valve cartridge

single

0770.766 Pump filter set 1/8" 10µ

(pck 5)

0770.723 Pump drive assy

0770.730 Pump sensor PCB

0770.739 Mixer 35 µL

0770.758 Mixer 100 µL

0770.740 Outlet filter 2µ

0770.735 Power supply

0770.732 Seal wash pump

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Part Description
number
0770.736 Degasser chamber

0770.715 Degasser SSV

connection block

0770.731 Solvent selection valve

Note: Text on bottom side when

mounted.
0770.727 Fan

0770.726 Prime pump

0770.720 Main board including

firmware. For OEM
versions of the pump
please contact the
manufacturer.
0770.722 Purge valve drive

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Part Description
number
0770.734 Mains inlet / switch /
fuses

0770.754 Purge valve

0770.755 Purge valve rotor seal

0700.005 Nut stainless steel 1/16”

(PCK/10)

0700.004 Ferrule stainless steel

1/16” (PCK/10)

0770.751 Flangeless nut PPS 1/8”

and ferrule. Brown (PCK
10)

0770.752 Flangeless nut Delrin

1/8” and ferrule. Black
(PCK 10)

0770.753 Flangeless nut 1/16” and

ferrule (PCK 10)

0770.721 Power switch panel

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Part Description
number
0770.733 Leak sensor

0770.747 Tubing silicone

7 mm OD – 3 mm ID (per
meter)

0770.748 Air tubing 1/16” OD - 1mm ID (per meter)

0770.749 PTFE tubing 1/8” OD - 1/16” ID (per meter)
0770.750 ETFE Tubing 1/16” OD - 1mm ID (per meter)
0770.757 Low pressure tubing set
0770.710 Toolkit 1299 pump

0770.790 Shipping box 1299 pump

A.2 Standard PM kit - Part # 0770.772

Part QTY Description

number
0770.315 4 Pump head
cartridge

0770.712 1 Lubrication kit.

Includes:
Lubrication tool 4
syringes with
grease.
0770.766 5 Pump filter 10µ

0770.737 4 High pressure seal

0770.738 4 Check valve

cartridge single

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Part QTY Description

number
0770.740 1 ASI 2 µ outlet filter

A.3 Premium PM kit - Part # 0770.764

Part QTY Description

number
0770.702 4 Piston cartridge
replacements kit
Includes: Piston and
pre-assembled seal
wash cartridge, low
pressure seal,
ceramic piston guide
0770.712 1 Lubrication kit
Includes:Lubrication
tool4 syringes with
grease.
0770.766 5 Pump filter 10µ

0770.737 4 High pressure seal

0770.738 4 Check valve cartridge

single

0770.740 1 ASI 2 µ outlet filter

2002.535 1 Purge valve rotor seal

A.4 Basic PM kit - Part # 0770.765

Part QTY Description

number
0770.740 1 2 µ outlet filter

0770.737 4 High pressure seal

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Part QTY Description

number
0770.766 5 Pump filter 10µ

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0060.368-15 UHPLC Pump 770 Service Manual

Appendix B. Error Codes

Error Error Description Possible cause

Code
280 EEPROM WRITE Defect on main-board: Replace
ERROR
281 OPTIONS EEPROM Defect on main-board: Replace
ERROR
282 SETTINGS EEPROM Defect on main-board: Replace
ERROR
283 ADJUSTMENTS Defect on main-board: Replace
EEPROM ERROR
284 EEPROM ERROR IN Defect on main-board: Replace
LOG COUNTER
290 ERROR OCCURRED There have been 3 unsuccessful error
DURING INIT resets. The pump cannot initialize or
start a run.
340 PURGE VALVE: Check seal purge valve, torque might
DESTINATION be too high.
POSITION NOT
REACHED
705 PRESSURE IS ABOVE Blockage in flow path.
MAXIMUM
Maximum pressure setting to low.
706 PRESSURE IS BELOW Minimum setting to high
MINIMUM
710 NO STOP EVENT Check method
PROGRAMMED IN TIME
TABLE
711 STEP NOT Check method
PROGRAMMED
712 FAN 1 SPEED TOO Check for obstruction of the ventilation
SLOW on the rear.
Fan might be defect.
713 FAN 2 SPEED TOO Check for obstruction of the ventilation
SLOW on the rear.
Fan might be defect.
720 DEGASSER ERROR Vacuum not reached,
Vacuum chamber leak.
Pump defect
721 OFFSET ADJUSTMENT Pressure sensor defect

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Error Error Description Possible cause

Code
TOO LARGE PRIMARY Replace pump head
PUMP A
722 OFFSET ADJUSTMENT Pressure sensor defect
TOO LARGE PRIMARY
Replace pump head
PUMP B
723 OFFSET ADJUSTMENT Pressure sensor defect
TOO LARGE
Replace pump head
SECONDARY PUMP A
724 OFFSET ADJUSTMENT Pressure sensor defect
TOO LARGE
Replace pump head
SECONDARY PUMP B
725 GAIN ADJUSTMENT Pressure sensor defect
OUT OF RANGE
Replace pump head
PRIMARY PUMP A
726 GAIN ADJUSTMENT Pressure sensor defect
OUT OF RANGE
Replace pump head
PRIMARY PUMP B
727 GAIN ADJUSTMENT Pressure sensor defect
OUT OF RANGE
Replace pump head
PRIMARY PUMP A
728 GAIN ADJUSTMENT Pressure sensor defect
OUT OF RANGE
Replace pump head
PRIMARY PUMP B
730 TIMED EVENT OUTPUT Check I/O setting
NOT AVAILABLE
773 NO PRESSURE Pressure sensor defect or pump head
SENSOR PRIMARY missing
DRIVE PUMP A Replace / install pump head
774 NO PRESSURE Pressure sensor defect or pump head
SENSOR PRIMARY missing
DRIVE PUMP B Replace / install pump head
775 NO PRESSURE Pressure sensor defect or pump head
SENSOR SECONDARY missing
DRIVE PUMP A Replace / install pump head
776 NO PRESSURE Pressure sensor defect or pump head
SENSOR SECONDARY missing
DRIVE PUMP B Replace / install pump head
777 POWER FAILURE 24V Check power supply output.
778 COMPRESSIBILITY Air in pump head
ERROR PUMP A
Purge

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Error Error Description Possible cause

Code
779 COMPRESSIBILITY Air in pump head
ERROR PUMP B
Purge
821 Leakage detected Solvent in the leak tray.
Clean and check connections for
leakage.
827 Pump A control loop time Replace corresponding drive
out
828 Pump B control loop time Replace corresponding drive
out
829 The pressure of the Check for obstructions in the flow
primary pump A is too path. Loosen the tubing between the
high at start-up of the primary and the secondary pump
pump. heads and then loosen the outlet
check valve.

Reset the error and reinstall the check

valve and the tubing. Use a 1/2"
torque wrench (set to 8 Nm) to tighten
the check valve. Try to start the pump.
830 The pressure of the Check for obstructions in the flow
primary pump B is too path. Loosen the tubing between the
high at start-up of the primary and the secondary pump
pump. heads and then loosen the outlet
check valve.

Reset the error and reinstall the check

valve and the tubing. Use a 1/2"
torque wrench (set to 8 Nm) to tighten
the check valve. Try to start the pump.
831 The pressure of the Check for obstructions in the flow
secondary pump A is too path. Loosen the tubing between the

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Error Error Description Possible cause

Code
high at start-up of the primary and the secondary pump
pump. heads.

Reset the error and reinstall the

tubing. Try to start the pump.
832 The pressure of the Check for obstructions in the flow
secondary pump B is too path. Loosen the tubing between the
high at start-up of the primary and the secondary pump
pump. heads.

Reset the error and reinstall the

tubing. Try to start the pump.
837 Pump A primary encoder Replace corresponding drive
error
838 Pump B primary encoder Replace corresponding drive
error
839 Pump A secondary Replace corresponding drive
encoder error
840 Pump B secondary Replace corresponding drive
encoder error
841 Pump A primary position Replace corresponding drive
sensor error
842 Pump B primary position Replace corresponding drive
sensor error
843 Pump A secondary Replace corresponding drive
position sensor error
844 Pump B secondary Replace corresponding drive
position sensor error
845 Pump drive A primary is Check for new Firmware or replace
outside position limits. corresponding drive

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Error Error Description Possible cause

Code
Switch off the instrument
and switch it on again.
846 Pump drive B primary is Check for new Firmware or replace
outside position limits. corresponding drive
Switch off the instrument
and switch it on again.
847 Pump drive A secondary Check for new Firmware or replace
is outside position limits. corresponding drive
Switch off the instrument
and switch it on again.
848 Pump drive B secondary Check for new Firmware or replace
is outside position limits. corresponding drive
Switch off the instrument
and switch it on again.

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Appendix C. Storage, packaging, recycling and disposal

If the instrument needs to be stored, or shipped to a different location, proceed
as follows:

Prepare for storage:

1. Remove harmful mobile phase from the system by flushing all ports with
IPA.

2. Disconnect all solvent tubing to the pump.

3. Remove the tubing from and to the mixer and place stoppers in mixer
ports.

4. Remove the tubing from the pump outlet to the mixer and place a
stopper in the outlet on the purge valve.

5. Tubing to the outlet check valves can remain in place.

6. Remove the tubing of the seal wash unit; place stoppers in the seal wash
unit ports.

7. Disconnect the instrument from power, remove the power cord.

Prepare for dispatch:

1. Carry out the steps above.

2. Fill in a health & safety form for the instrument and include the form in
the package.

3. Use the original packaging materials to package the instrument for

dispatch. See below for packing instructions.

4. Make sure any tax/import/export requirements are met.

Decontamination
The instrument must be decontaminated before decommissioning and all local
regulations shall be followed with regard to scrapping of the equipment.

General instructions for disposal

When taking the instrument out of service, the different materials must be
separated and recycled according to national and local environmental
regulations.

Hazardous substances
The instrument contains hazardous substances. Contact the manufacturer for
more detailed information.

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Disposal of electrical components

Waste of electrical and electronic equipment must not be disposed as
unsorted municipal waste and must be collected separately. Please
contact an authorized representative of the manufacturer for
information concerning the decommissioning of equipment.

Packaging instructions
Use the original packing materials if the instrument needs to be shipped.

Figure 41: : Packaging instructions

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0060.368-15 UHPLC Pump 770 Service Manual

Appendix D. PCB layout

The main board contains electrostatic sensitive parts. Use proper

grounding techniques to prevent damage to the board.

Figure 42: Main board

1. Primary pump drive A

2. Secondary pump drive A

3. Secondary pump dive B

4. Primary pump drive B

5. Ground from power supply

6. 24 VDC from power supply

7. Degasser

8. Selection valve A and B

9. Backwash pump

10. Fan 1

11. Fan 2

12. Prime pump

13. Purge valve sensors

14. Purge valve motor

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Appendix E. Exploded views

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0070.302

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Index

A L
About this manual 5 Log counters 15
Access degasser 27 Low pressure tubing 37
Access support pumps 27 Lubrication spindle 19
Advanced pressure view 23 Lubrication wizard 19
Appendix C. Storage, packaging, M
recycling and disposal 50 Main board replacement 29
B Maintenance 18
Basic PM kit 43 P
C Parts 10
Calibration wizard 17, 19 PCB layout 52
Check valve replacement 20 PCB programming 16
Control software 12 Performance inspection 35
D Pictorials 5
Decontamination 50 Piston replacement 18
Diagnostics 23 Power supply remove 30
Disassembly 27 Premium PM kit 43
Dynamic leak test 16, 25 Pressure 14
E Pressure graph 14
Error Codes 45 Pressure pulsating 24
Exploded views 53 Pressure view 23
F Pressure view XE 23
Firmware upload 16 Production 16
Flow accuracy 35 Pump drive replacement 31
Flow incorrect 24 Pump head maintenance 17
Flow settings 13 Purge valve drive replacement 29
Flow unstable 25 Purge valve replacement 21
H R
High pressure tubing 36 Remove top cover 27
I Removing power supply 30
I/O control 15 Removing the top cover 27
Instrument - front 10 Replacement
Instrument - rear 11 Piston 18
Internal tubing 37 Seal 18

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Replacing
Check valve 20
Main board 29
Pump drive 31
Purge valve 21
Purge valve drive 29
Selection valve 29
Vacuum chamber 29
S
Safety instructions 6
Seal replacement 18
Selection valve replacement 29
Serial number 16
Service Menu 12
ServiceLink
Using 12
Spares and Accessories 36
Spindle lubrication 19
Standard PM kit 42
System setup 35
T
Top cover
Remove 27
Trouble shooting 23
Tubing
High pressure 36
Internal 37
Low pressure 37
V
Vacuum chamber replacement 29
W
Wizards and tests 16

63