Psych
Psych
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ETIOLOGICAL IMPLICATIONS - The cause of schizophrenia is still uncertain. Most likely no single
factor can be implicated in the etiology; rather, the disease probably results from a combination of
influences including biological, psychological, and environmental factors
1. Biological Influences - Genetics - Twin Studies, Adoption Studies
2. Biochemical Influences - abnormal brain biochemistry “chemical disturbance”
• Dopamine Hypothesis - caused by an excess of dopamine dependent neuronal activity in the
brain.
• Other Biochemical Hypotheses- Abnormalities in the neurotransmitters norepinephrine,
serotonin, acetylcholine, and gamma-aminobutyric acid and in the neuro regulators, such as
prostaglandins and endorphins, have been suggested.
3. Physiological Influences
• Viral Infection - high incidence of schizophrenia after prenatal exposure to influenza
• Anatomical Abnormalities - Ventricular enlargement is the most consistent finding; however,
sulci enlargement and cerebellar atrophy are also reported.
4. Psychological Influences -family relationship factors as major influences, early theories
implicated poor parent-child relationships and dysfunctional family systems as the cause of
schizophrenia, but they no longer hold any credibility. Researchers now focus their studies in
terms of schizophrenia as a brain disorder.
5. Environmental Influences
• Sociocultural Factors - lower socioeconomic classes experience symptoms associated with
schizophrenia than do those from the higher socioeconomic groups
• Stressful Life Events -There is no scientific evidence to indicate that stress causes
schizophrenia, may contribute to the severity and course of the illness
TYPES OF SCHIZOPHRENIA AND OTHER PSYCHOTIC DISORDER
1. DELUSIONAL DISORDER - characterized by the presence of delusions that have been experienced
by the individual for at least 1 month (APA, 2013).
Subtypes of delusional disorder include the following:
• Erotomanic Type - the individual believes that someone, usually of a higher status, is in love
with him or her. Famous persons are often the subjects of erotomanic delusions.
• Grandiose Type - have irrational ideas regarding their own worth, talent, knowledge, or power.
They may believe that they have a special relationship with a famous person, or even assume
the identity of a famous person
• Jealous Type - delusions centers on the idea that the person’s sexual partner is unfaithful. The
idea is irrational and without cause, but the individual with the delusion searches for evidence
to justify the belief.
• Persecutory Type - individuals believe they are being persecuted or malevolently treated in
some way, cheated or defrauded, followed and spied on, poisoned, or drugged.
• Somatic Type - Individuals with somatic delusions believe they have some type of general
medical condition.
2. BRIEF PSYCHOTIC DISORDER - sudden onset of psychotic symptoms that may or may not be
preceded by a severe psychosocial stressor. These symptoms last at least 1 day but less than 1
month experiences emotional turmoil or overwhelming perplexity or confusion.
• Individuals with preexisting personality disorders (most commonly histrionic, narcissistic,
paranoid, schizotypal, and borderline personality disorders) appear to be susceptible to this
disorder (Sadock & Sadock, 2007). Catatonic features may also be associated with this disorder.
3. Schizophreniform Disorder - The essential features of schizophreniform disorder are identical to
those of schizophrenia, with the exception that the duration, including prodromal, active, and
residual phases, is at least 1 month but less than 6 months (APA, 2013)
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4. Schizoaffective Disorder - associated with the mood disorders (depression or mania). The client
may appear depressed, with psychomotor retardation and suicidal ideation, or symptoms may
include euphoria, grandiosity, and hyperactivity
Content of Thought
Delusions - false personal beliefs
• Delusion of Persecution - feels threatened and believes that others intend harm or persecution
toward him or her
• Delusion of Grandeur - exaggerated feeling of importance, power, knowledge, or identity
• Delusion of Reference - All events within the environment are referred by the psychotic person
to him- or herself
• Somatic Delusion - has a false idea about the functioning of his or her body
• Nihilistic Delusion - has a false idea that the self, a part of the self, others, or the world is
nonexistent
• Religiosity- excessive demonstration of or obsession with religious ideas and behavior.
• Paranoia - have extreme suspiciousness of others and of their actions or perceived intentions
(e.g., “I won’t eat this food. I know it has been poisoned.”).
• Magical Thinking - the person believes that his or her thoughts or behaviors have control over
specific situations or people. e.g. “It snowed last night because I wished very, very hard that it
would.”
Form of Thought
• Associative Looseness - Thinking is characterized by speech in which ideas shift from one
unrelated subject to another.
• Neologisms - psychotic person invents new words that are meaningless
• Concrete Thinking - literal interpretations of the environment, represents a regression to an
earlier level of cognitive development.
• Clang Associations - often take the form of rhyming. e.g “It is very cold. I am cold and bold. The
gold has been sold.”
• Word Salad - is a group of words that are put together randomly, without any logical
connection (e.g., “Most forward action grows life double plays circle uniform.”).
• Circumstantiality - the individual delays in reaching the point of a communication because of
unnecessary and tedious details.
• Tangentiality - Unrelated topics are introduced, and the focus of the original discussion is lost.
• Mutism - is an individual’s inability or refusal to speak
• Perseveration - persistently repeats the same word or idea in response to different questions
Perception
• Hallucinations -false sensory perceptions not associated with real external stimuli, may
involve any of the five senses.
• Auditory
• Visual
• Tactile
• Gustatory
• Olfactory
• Illusions - misperceptions or misinterpretations of real external stimuli.
Sense of Self - Sense of self describes the uniqueness and individuality a person feels. Because of
extremely weak ego boundaries, the individual with schizophrenia lacks this feeling of
uniqueness and experiences a great deal of confusion regarding his or her identity.
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• Echolalia - repeat words that he or she hears
• Echopraxia - purposelessly imitate movements made by others.
• Identification and Imitation - Identification which occurs on an unconscious level, and
imitation, which occurs on a conscious level, are ego defense mechanisms used by individuals
with schizophrenia and reflect their confusion regarding self-identity.
• Depersonalization - unstable self-identity of an individual with schizophrenia may lead to
feelings of unreality (e.g., feeling that one’s extremities have changed in size; or a sense of
seeing oneself from a distance).
Affect- describes the behavior associated with an individual’s feeling state or emotional tone.
• Inappropriate Affect - inappropriate when the individual’s emotional tone is incongruent
with the circumstances (e.g., a young woman who laughs when told of the death of her
mother).
• Bland or Flat Affect - described as bland when the emotional tone is very weak. The
individual with flat affect appears to be void of emotional tone
• Apathy - often demonstrates an indifference to or disinterest in the environment.
Avolition- the individual with schizophrenia, this may take the form of inadequate interest,
motivation, or ability to choose a logical course of action in a given situation.
• Emotional Ambivalence -fear of intimacy
• Deteriorated Appearance - Personal grooming and selfcare activities may be neglected.
Interpersonal Functioning and Relationship to the External World - social isolation, emotional
detachment, and lack of regard for social convention.
• Impaired Social Interaction - exhibiting behaviors that are not socially and culturally
acceptable.
• Social Isolation -exclusion of the external environment
Psychomotor Behavior
• Anergia - lack sufficient energy to carry out activities of daily living or to interact with others.
• Waxy Flexibility - allows body parts to be placed in bizarre or uncomfortable positions for
long periods.
• Posturing - voluntary assumption of inappropriate or bizarre postures.
• Pacing and Rocking - Pacing back and forth and body rocking
Associated Features
• Anhedonia - inability to experience pleasure. This is a particularly distressing symptom that
compels some clients to attempt suicide
• Regression - retreat to an earlier level of development. Regression, a primary defense
mechanism of schizophrenia
PERSONALITY DISORDER
According to WHO abnormal personality can be defined as "deeply ingrained maladaptive
pattern of behavior, continuing throughout the most of adult life, although often becoming
less obvious in middle or old age.
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● It is long lasting, most of the time lifelong problems.
● It causes significant impairment in social oroccupational functioning.
● It produces distress to the individual and to others.
● Whereas the symptoms of personality disorder are continuous and start from
adolescence or even before.
● These patients are odd but not mad.
ETIOLOGY FACTORS:
1. Biological factors.
2. Developmental factors.
3. Social cultural factors.
4. Psychological stressors.
PERSONALITY DISORDERS
Types: The following are the classical types of Personality Disorders.
1. Schizoid Personality Disorder
2. Paranoid Personality Disorder
3. Antisocial Personality Disorder
4.. Histrionic Personality Disorder
5. Obsessive-Compulsive Personality Disorder
CLASSIFICATION
● Cluster A: Odd, aloof features - paranoid, schizoid, schizotypal.
● Cluster B: Dramatic, impulsive, and erratic features - Borderline, Antisocial,
Narcissistic, histrionic
● Cluster C: Anxious and fearful features - Avoidant, Dependent,
Obsessive-compulsive
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● Relationships of no interest
● Sexual experiences not of interest
● Activities not enjoyed
● Friends lacking
● Emotionally cold and detached
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● Promiscuity.
● Poor impulse control.
● Avoids responsibility for actions.
● Abusive and manipulative of others.
● Abuse of substance is a common association.
● Requires constant stimulation.
● Shallow emotions with lack of care for the feelings of others.
● N.B. Likely to abuse relation with doctor to obtain benefits and avoid responsibility.
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● Fantasizes about unlimited success, brilliance, etc.
● Arrogant
● Manipulative
● Envious of others
● Grandiose sense of importance
● Associates with special people
● Me first attitude
● Empathy lacking for others
Obsessive-Compulsive Personality
"LOW MIRTH"
● Leisure activity is minimal
● Organizational focus
● Work and productivity predominate
● Miserly spending habits
● Inflexible around morals, values, etc.
● Rigidity and stubbornness
● Task completion impaired (by perfectionism)
● Hoards items - cannot discard them
Treatment: The aim of treatment is to improve the social adaptation and vocational
functioning of the patient, as well as to reduce the suffering of his surrounding family
members.
● Psychotherapy: - The modality and type is chosen according to the individual
patient.
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● Techniques vary from cognitive behavioral, brief dynamic and extended deeper
forms.
● Group therapy can be extremely helpful in certain types of personality disorders, e.g.
Schizoid Personality Disorder.
● Individual psychotherapy is more helpful in certain cases, e.g. a well motivated
Paranoid personality disorder.
Personality disorder is different from mental illness. Whereas the symptoms of personality
disorder are continuous and start from adolescence or even before.
● It is not a mental illness.
● It is a maladaptive behavior.
● It is long lasting, most of time lifelong problems.
● It produces distress to the individual and to others.
ANXIETY DISORDERS
Fear - fear is an emotional response to a real or perceived threat.
Anxiety- is a subjective feeling of fear and uneasiness to an unknown threat or internal
conflict
● Anxiety is the body's natural response to stress that causes increased alertness, fear,
and physical signs.
● Anxiety disorders include disorders that share features of excessive fear and anxiety
and related behavioral disturbances.
● Individuals with anxiety disorders usually overestimate the danger in the situation
● Many of the anxiety disorders develop during childhood and tend to persist if not
treated.
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● It is excessive or persisting beyond developmentally appropriate period
● It is out of proportion to the situation creating it.
● It interferes with social, occupational or other important areas of functioning.
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CLASSIFICATION OF ANXIETY DISORDERS
● Separation anxiety disorder
● Selective mutism
● Specific phobias
● Social anxiety disorder
● Panic disorder
● Agoraphobia
● Generalized anxiety disorder
● Substance/ medication induced anxiety disorder
● Anxiety disorder due to another medical condition
● Other specified anxiety disorder
● Unspecified anxiety disorder
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Psychoanalytic theory
● According to the Freud's psychoanalytic theory anxiety is the result of inability of the
ego defense mechanism to resolve the conflict between ID and superego
● Repression helps in dealing the anxiety producing situations without symptom
formation.
● If repression is unsuccessful as a defense mechanism, other defense mechanisms
(conversion, displacement, regression) are used. This defense mechanisms may
cause symptoms that produce a picture of neurotic disorder.
Behavior theory
● This theory explains that anxiety is a conditioned or learned response to a specific
environmental stimulus.
● e.g. a person not having food allergies, may get sick after eating contaminated food
at a restaurant. Through generalization the person can distress all food prepared by
others.
● The individual may also learn to have an internal response of anxiety, intimating the
anxiety response of his parents or significant others (social learning)
Psychosocial factors
● Disturb mother child relationship
● Object loss theory
● Stressful life events
● Certain temperament or personality traits
● Childhood maltreatment (abuse or neglect)
● Overprotective parents
● Family environment
Symptoms of anxiety
Physical
● Dry mouth
● Difficulties swallowing
● Palpitations
● Restlessness, tremor
● Gastrointestinal discomfort
● Headache
● Choking sensation
● Breathlessness
● Dilated pupils
● Muscle tension
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● Tightness of chest
● Excessive thirst
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● Strong persistent fear of an interpersonal situation
● Fear of meeting unfamiliar people
● Fear or avoidance of situations in which the person can be observed eating or
drinking
● Fear of being criticized
● Fear of public speaking or public performance
Specific phobias
- Specific phobias are characterized by unrealistic and unreasonable fear related to a
specific object or situation
- Exposure to phobic stimulus provokes an immediate anxiety response which may
take form of a panic attack
- Examples of specific phobias are acrophobia, hematophobia, claustrophobia,
zoophobia etc
Agoraphobia
- Agoraphobia can be defined as a fear of being at places or situations where rapid
exit is not possible or it is difficult to obtain help.
- The person has a fear of being trapped and helplessness
This may include:
● Enclosed spaces ( movie theaters, elevators, stores)
● Open spaces ( parking lots, bridges)
● Public transport (bus, aeroplane, train)
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- People with gad have persistent excessive at realistic worry associated with muscle
tension impaired concentration and insomnia.
- GAD is more common among women (widowed, divorce, unemployed, house
makers)
Antidepressants
- Modern antidepressants (SSRI and SNRIs) are typically the first line treatment for
anxiety disorder.
- Examples of SSRI are escitalopram ( Lexapro) and fluoxetine (Prozac). SNRI include
duloxetine ( Cymbalta) and venlafaxine ( Effexor)
- Bupropion. This is another type of antidepressant commonly used to treat chronic
anxiety
Second line treatment
● Benzodiazepines. Benzodiazepines are sedatives that can help relax your muscles
and calm your mind. They work by increasing the effects of certain neurotransmitters.
● Examples are alprazolam (Xanax) and clonazepam ( Klonopin)
● Buspirone (BuSpar). This anti anxiety drug is used to treat both short term and
chronic anxiety
● Beta- blockers. Treat physical symptoms of anxieties such as a raising heart, severe
palpitations, trembling or shaking
● Anticonvulsants. Used to prevent seizures and also relieve certain anxiety disorder
symptom
Psychotherapy
Cognitive behavioral therapy (CBT)
- Cognitive behavior therapy is focused on turning the negative, orphanic causing
thoughts and behaviors into positive ones.
- The client is trained to carefully approach and manage careful or worry some
situations without anxiety
Behavior techniques
● Biofeedback
● Systematic desensitization (effective in phobias)
● Flooding
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Relaxation techniques
● Progressive muscle relaxation techniques
● Yoga
● Meditation
● Deep breathing exercise
Nursing diagnosis
1. Panic anxiety related to real or perceive threat passively evidence by restlessness
and poor impulse control
2. Ineffective coping related to lack of coping resources possibly evidence by ritualistic
behavior or inability to meet basic needs
3. Powerlessness related to fear of disapproval from others possibly evidence by
dependence on others and verbal expressions of having no control
4. Social isolation related to panic level of anxiety possibly evidence by withdrawn
behavior and insecurity in public
5. Deficient knowledge related to unfamiliarity with medications use and potential
adverse effects possibly evidenced by verbalising a deficiency in knowledge on skill
or request information.
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● Help the patient to identify areas of life situation that patient can control
● Help the patient to verbalize his or her feelings
MOOD DISORDERS
● Mood: prevailing internal emotional state
● Affect: external display of feelings
● Mood disorders are a category of illnesses that describe a serious change in mood
Etiology
Biological Factors
● More common in monozygotic twins
● Unipolar depressions in a parent
● Abnormalities in amine neurotransmitter
● Neuroendocrine abnormalities in hypothalamic pituitary adrenal (HPA) axis.
Psychological factors
● Major life events
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● Interpersonal relations, absent or unsatisfactory significance special bonds have
negative effects on self regards
● Rapid hormonal changes
● Distorted thinking
● Lose hopefulness
Diagnosis
● Depressed mood
● Anhedonia- inability to feel pressure
● Guilt
● Sleep disturbances
● Appetite
● Energy
● Concentration
● Psychomotor
● Suicidality
Differential diagnosis
1. Other psychiatric disorders, sleep disturbances, and neurological disorders
2. Endocrine disorders: Addison's disease, Cushing's disease, Hyper/hypothyroidism,
Perimenstrual syndromes
3. Metabolic Disorders: Hypoglycemia, hypercalcemia, porphyria (hemoglobin
abnormally metabolized
4. Hematological Disorders: anemia
5. Inflammatory condition: SLE
6. Infections: syphilis, lyme disease, HIV encephalopathy
7. Medication related: anti hypertensive, steroids
8. Substance misuse: alcohol, benzodiazepines, opiates, marijuana, etc.
Management
Hospitalization if there is:
● Serious risk of suicide
● Serious risk of harm to others
● Significant self neglect
● Severe depressive symptoms
● Severe psychotic symptoms
● Lack of breakdown of social supports
● Initiation of ECT
● Treatment resistant depression
● I need to address comorbid conditions
TREATMENT
First line treatment: antidepressant
● Effective in 65 to 75% of patients
● Patient factor: age, sex, comorbid illness, previous response to antidepressants
● Symptomatology: sleep problem (sedative agents), lack of energy/hypersomnia
(adrenergic stimulatory agents), OCD symptoms (clomipramine), risk of suicide
(avoid TCA)
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Tricyclic antidepressants TCA
Action: reuptake inhibition of norepinephrine and serotonin, increasing both in synaptic cleft
● Examples:
○ Imioramine ( Tofranil)
○ Clomipramide (Anafranil)
○ Amitriptyline (Tryptizol)
● TCA are cheap drugs but have many side effects.
Electroconvulsive therapy
- Maybe use when there are severe biological features ( significant weight loss or
reduce appetite) or marked psychomotor retardation
Dysthymic Disorder
● Mild, chronic depression for at least 2 years
● Common psychiatric comorbidities: major depression (up to 75%), “double
depression” anxiety disorders (up to 50%), personality disorders (20-40%)
somatoform disorders (2.8% - 45.2%), substance abuse (up to 50%)
● Difficult to diagnose due to soft mood symptoms, distracting comorbidities and lack of
patient recognition
● Treatment include psychotherapy mainly
Bipolar disorders
- Known as manic depressive illness
- A brain disorder
- Causes unusual shifts in mood energy activity levels in the ability to carry out day to
day tasks
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Symptom and Signs
Manic Episode
● Feel very “up “high” or elated
● A lot of energy
● Increase activity levels
● Trouble sleeping
● Talk really fast about a lot of different things
● Be agitated, irritable or touchy
● Feel like their thoughts are going very fast
● Think they can do a lot of things at once
● Do risky things like spend a lot of money or have reckless sex
Depressive Episode
● Very sad, down, empty, or hopeless
● Decrease activity levels
● Trouble sleeping, then may sleep too little or too much
● Feel like they can't enjoy anything
● Feel worried and empty
● Trouble concentrating
● Forget things a lot
● Eat too much or too little
● Feel tired or slow down
● Think about that or suicide
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Lithium
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● Level of lithium (0.5 to 1.5 meq/L)
● Increase urination (polyuria)
● Tremors- fine hand
● Hydration
● Increase peristalsis
● U2- 4 weeks effective
● Increase bowel movement
● Mouth is dry
○ Assess function of kidney
○ Toxicity: nausea and vomiting, diarrhea
Antidepressants
● SSRI
○ Selective serotonin reuptake inhibitor
○ Safest
○ Side effects are low
○ 1 to 4 weeks
○ Prozac, paxil, zoloft, luvox
● TCA
○ Tricyclic antidepressants
○ 2-4 weeks
○ Anticholinergic
○ Amitriptyline, nortriptyline, doxepin, trimipramine, amoxapine, anafranil,
venlafaxine
● MAOI's
○ Increase all neurotransmitters
○ 2-6 weeks
○ Hypertensive crisis
○ Don't take:
■ Avocado
■ Aged cheese
■ Beer/b6 thiamine
■ Chocolate
■ Fermented foods
■ Soy sauce
Suicide
- The intentional act of killing oneself
- Suicidal ideation- means thinking about oneself
- Passive suicidal ideation- when a person thinks about one thing to die or wishes he
or she were dead but has no plans to cause his or her death
- Active suicidal ideation- when a person thinks about and seeks to commit suicide
Precipitating Factors
- Social isolation- have difficulty forming and maintaining relationships
Norman Cousins story:
A woman who committed suicide had written in her diary everyday during the week before
her death “nobody called today”, “nobody called today”
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- Severe life events- divorce, death, sickness, leg problems, interpersonal discord.
- Sensitivity to loss- may react tragically to separation or loss of a loved one
Suicide precautions
● Execute a no suicide contract. The client informs the nurse when he or she has
suicidal ideations
● Ask direct questions. Find out if the person specific plan for suicide. Determine what
method
● Be alert for cries for suicide
● Provide a safe environment and protect client from self
● Encourage to vent feelings and thought
● Give emotional support
● Make the patient realize that the tendency to commit suicide is due to the disturbance
in the brain chemistry and is treatable once they know that an episode of suicidal
thinking will pass, baby likely not act on the impulse
● Provide structured scheduled and involved in activities with other to increase self
worth and divert attention
● On discharge: help patient create plan for life
● Always remember:
○ That a suicidal person want to die only during the period of suicidal
crisis-during this time the person is ambivalent about living and dying
○ Suicidal people gives warning
○ Persons recovering from depression are high risk for 9 to 15 months after
recovery
○ Suicidal people are extremely unhappy but not always mentally ill
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COGNITIVE DISORDERS
COGNITION
- information processing, This definition encompasses the acquisition of sensory
information, the storage, retrieval, and use of that information for making behavioral
decisions." (Rowe & Healy, 2014)
EXAMPLES
● Perception
● Attention
● Memory retrieval
● Problem solving
● Decision making
● Judgment formation
● Imagery visualization
● Language comprehension
● Inductive Reasoning
● Concept formation
COGNITIVE DISORDER
- Is a disruption or impairment in the higher- level functions of the brain.
- Devastating effects on the ability to function in daily life.
- Can cause people to forget the names of the family members, to be unable to
perform daily tasks, and to neglect personal hygiene.
PRIMARY CATEGORIES
*DELIRIUM
*DEMENTΙΑ
*AMNESTIC DISORDERS
Delirium
● Characterized by disturbance of consciousness and a change in cognition such as
impaired attention span and disturbances in consciousness that develop over a short
period of time.
● Classified as mild to severe.
● Sundowning
SYMPTOMS
● Difficulty with attention
● Easily distractible
● Disoriented
● May have sensory disturbances such as illusions, misinterpretations, or
hallucinations
● Can have sleep- wake cycle disturbances
● Changes in psychomotor activity
● May experience anxiety, fear, irritability, euphoria, or apathy
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TREATMENT
Primary treatment: identify any causal or contributing medical conditions.
NURSING MANAGEMENT
● Client's safety is a priority.
● Meet their physiologic and psychologic needs.
● Behavior, mood, and level of consciousness of these clients can fluctuate rapidly
throughout the day.
DEMENTIA
● A mental disorder that involves multiple cognitive deficits, primarily memory
impairment, and at least one of the following disturbances:
● Aphasia: deterioration of language function.
● Apraxia: inability to execute motor functions despite intact memory abilities.
● Agnosia: inability to recognize or name objects despite intact sensory abilities.
● Disturbance in executive functioning, which is the ability to think abstractly and to
plan, initiate, sequence, monitor, and stop complex behavior.
Aphasia
● Usually begins with the inability to name familiar objects or people and then
progresses to speech that becomes vague or empty with excessive use of terms
such as "it" or "thing."
May exhibit:
● Echolalia: echoing what is heard
● Palilalia: repeating words or sounds over and over
Apraxia: May cause clients to lose the ability to perform routine self-care activities such as
dressing or cooking.
Disturbances in executive functioning: evident due to inability to learn new material, solve
problems, or carry out daily activities.
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Moderate: confusion is apparent, along with progressive memory loss.
● Can no longer perform complex tasks but remains oriented to person and place.
● Still recognizes familiar people.
● Toward the end of the stage, the person loses the ability to live independently and
requires assistance because of disorientation to time and loss of information such as
address.
Alzheimer's disease
● Progressive brain disorder that has a gradual onset but causes an increasing decline
of functioning, including loss of speech, loss of motor function, and profound
personality and behavioral changes such as paranoia, delusions, hallucinations,
inattention to hygiene, and belligerence.
● Evidenced by: atrophy of cerebral neurons, senile plaque deposits, and enlargement
of the third and fourth ventricles of the brain.
Head Trauma
● Dementia can be a direct pathophysiologic consequence.
● Degree and type of cognitive impairment and behavioral disturbance depend on the
location and extent of the brain injury.
● When it occurs as a single injury, the dementia is usually stable rather than
progressive. Repeated head injury may lead to progressive dementia.
Huntington's Disease
● An inherited, dominant gene disease that primarily involves cerebral atrophy,
demyelination, and enlargement of brain ventricles.
● Initially, there are choreiform movements that are continuous during waking hours
and involve facial contortions, twisting, and turning, and tongue movements.
Parkinson's disease
● Slowly, more progressive condition characterized by tremor, rigidity, bradykinesia,
and postural instability.
● Results from loss of neurons of the basal ganglia.
● 20%-60% has dementia
Delirium Vs Dementia
Delirium
Onset: Usually sudden
Course: Usually brief with return to usual level of functioning
Age group: any
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Dementia
Onset: Usually gradual
Course: Usually long-term and progressive, occasionally maybe arrested or reversed
Age group: elderly
Nursing Interventions
Promoting patient's safety and protecting from injury.
● Offer unobtrusive assistance with or supervision of cooking, bathing, or self-care
activities.
● Identify environmental triggers to help clients avoid them.
EATING DISORDERS
- Eating disorders are mental illnesses that cause serious
disturbances in a person's everyday diet.
- It can manifest as eating extremely small amounts of food or
severely overeating.
- The condition may begin as just eating too little or too much but
obsession with eating and food takes over the life of a person
leading to severe changes.
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TYPES OF EATING DISORDERS
● Anorexia Nervosa
● Bulimia Nervosa
● Binge Eating Disorder
● Not Otherwise Specified (NOS)
ANOREXIA NERVOSA
- Anorexia nervosa happens when one is obsessed with becoming
thin that they reach extreme measures and this leads to extreme
weight loss.
Etiology
● A specific cause for eating disorders is unknown. Initially dieting
may be the stimulus that leads to their development. Biologic
vulnerability, developmental Problems and family and social
influences can turn dieting into an eating disorder.
● Disturbance in hypothalamus
● Many neurochemical changes accompany eating disorders, but it
is difficult to tell whether they cause or result from eating disorders.
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Diagnostic findings
● History collection
● Physical examination
● Complete blood count
● Liver profile
● Electrolytes
● Blood glucose levels
● ECG
Complications
● Increased susceptibility to infection
● Hypoalbuminemia
● Chronic inflammatory bowel disease
● Esophageal erosion, ulcers, bleeding, dental caries (due to
frequent vomiting)
● Cardiovascular issues
● Amenorrhea
Medical management
- Medical management focuses on weight restoration, nutritional
rehabilitation and correction of electrolyte imbalances.
Pharmacotherapy
● Neuroleptics
● Appetite stimulants
● Antidepressants
Psychological therapies
● Individual psychotherapy
● Behavioral therapy
● cognitive behavior therapy
● Family therapy
Nursing interventions
● Maintain strict intake and output chart
● Monitor status of skin and oral mucous membranes
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● Short term management is focused on ensuring weight gain and
correcting nutritional deficiencies.
● Eating must be supervised by the nurse and a balanced diet of at
least 3000 calories should be provided in 24 hours
● Monitor electrolyte levels.
● Weight should be checked regularly
● Control vomiting by making the bathroom inaccessible for at least
2 hours after food.
● In extreme cases when a patient refuses to eat and comply with
the treatment, gavage feedings may need to be instituted.
● Encourage families to participate in education regarding the
connection between family processes and the patient's disorder.
BULIMIA NERVOSA
- Bulimia nervosa is characterized by episodes of binge eating
followed by feelings of guilt, humiliation and self-condemnation.
- Clients with bulimia nervosa report dissatisfaction with their bodies,
as well as they believe that they are fat, unattractive and
undesirable.
Etiology
● Family history of mood or anxiety disorders (e.g,
obsessive-compulsive disorder) places a person at risk for an
eating disorder.
● Altered serotonin levels in brain
● Society's emphasis on appearance and thinness
● Sexual abuse
● Struggle for control or self-identity
● Learned maladaptive behavior
Clinical features
● Heartburn
● Persistent sore throat
● Callused or scarring on back of hands and knuckles.
● Tooth staining or discoloration
● Loss of dental enamel
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● Increased dental caries
● Normal or slightly overweight appearance.
● Epigastric or abdominal pain
● Amenorrhea
● Fluid and electrolyte imbalance
● Poor impulse control
● Low tolerance for frustration
● Excessive exercise regimen
● Withdrawal from friends.
Diagnostic findings
● History collection
● Physical examination
● Psychological evaluation and beck depression inventory
● Blood investigations (Electrolytes, blood glucose)
● ECG
● Medical evaluation to rule out Gastrointestinal disorder.
Medical management
● Psychotherapy
● SSRI’s
● Cognitive behavioral therapy
● Most clients with bulimia are treated on an outpatient basis.
Hospital admission is indicated if binging and purging behaviours
are out of control and the client's medical status is compromised.
Complications
● Dehydration or electrolyte imbalances
● Chronic, irregular bowel movements
● Constipation
● Increased risk of suicide
● Gastric rupture during periods of binge eating
● Dental caries and gum infections.
Nursing care
● Encourage patient to recognize and verbalize her feelings about
her eating behavior
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● Provide assertiveness training
● Explain risks of emetic, laxative and diuretic abuse
● Set a time limit for each meal.
KEY POINTS
Chronic condition
● Prognosis varies by IQ and severity
● More common in males (1.6:1), except severe cases
● Causes: genetic disorders (e.g., Down syndrome), environmental factors (such as
neglect or abuse), prenatal issues (like maternal illness, alcohol, drugs, poor
nutrition), postnatal problems (including malnutrition, infections, head injuries)
● Treatment: behavioral therapy (e.g., social skills training), communication therapy
(e.g., speech therapy), supported living, job coaching, mainstreaming in schools
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LEARNING DISORDER
TIC DISORDER
- are neurological conditions marked by sudden, repetitive, nonrhythmic movements or
vocalizations called tics. These can range from simple motor tics, like eye blinking or
shoulder shrugging, to complex vocal tics involving words or phrases.
TYPES
1. Motor tics = Involuntary movements
● Cause = Contraction of muscles
● (A) Simple Motor tics = head shaking, eye blinking,
● sniffing, shoulder shrugging,grimace
● (B) Complex motor tics = head banging, lip biting, gesture
2. Vocal tics = Clearing the throat humming
● (A) Simple vocal tics = coughing, barking, throat clearing.
● (B) Complex vocal tics = Echolalia,coprolalia(abuse language use)
MANAGEMENT
1. Drug therapy
● Haloperidol 0.5-6mg(antipsychotic drug)
● Pimozide 1-10mg
● Clonidine 0.05-0.25mg
2. Behavioral therapy
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3. Individual and family counseling therapy
ADHD
ADHD includes two main syndromes:
● In attention and hyperactivity-impulsivity
● Syndromes can occur separately or together often with overlapping symptoms
● Symptoms start before age 7
● Symptoms can cause impairment in two or more settings
Hyperactivity
● Fidgets or squirms in seat
● Difficulty staying seated
● Excessive running, climbing, or restlessness
● Trouble playing quietly
● Acts “driven by a motor”
● Tox excessively
Impulsivity
● Blurted out answers
● Impatience, difficulty waiting turn
● Interrupts or intrudes on others
Subtypes of ADHD
● Predominantly inattentive
● Predominantly hyperactive-impulse
● Combined
Typical Onset: Between 3 and 4 years old
● Persistence: 68% continue to have symptoms into adulthood; inattentive subtype is
more common in adolescents and adults
● Gender difference: male to female ratios range from 2:1 to 9:1; combined and
hyperactive types are more frequent in males
● Prevalence: affects 3-7% percent of school age children
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● Peer rejection and low self esteem
● Low frustration tolerance and frequent tantrums
● Mood swings, bossiness and stubbornness
● Increase risk of accidents
● Driving difficulties, including speeding and accidents
Treatments
● Medications
○ Ritalin- stimulant
○ Wellbutrin- to help manage symptoms.
● Psycho education and reading materials- (bibliotherapy) can help you understand the
condition better
● Building skills: training and things like managing your time, staying organised,
studying effectively, solving problems, and improving social skills can make a big
difference.
Conduct Disorder
- Involves a repetitive, persistent pattern of behavior or violating others rights or major
societal norms.
- Diagnosis requires at least 3 of the following behaviors in the past 12 months, with at
least one present in the past 6 months:
a. Aggression toward people or animals
b. Destruction of property
c. Deceitfulness or theft
d. Serious rule violations
Destruction of property
● Deliberate fire setting
● Deliberate destruction of others property
Deceitfulness or theft
● Breaking and entering
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● Lying: conning
● Stealing; shoplifting; forgery
Specifiers
● Mild: few conduct problems beyond diagnosis criteria; minor harm caused
● Moderate: intermediate number of problems and impact
● Severe: many problems behind diagnosis criteria; considerable harm caused
Autism
- Autism spectrum disorder are a group of disorders with common disabilities in three
key areas
- Social awareness and interaction
- Language and other communication skills
- Imaginative play
- Autism consists of disorders of development of brain functions
- Causes are not yet known for sure
Labels of autism
Autistic savants: distinctive abilities in art music mathematics or memory. 1% in the whole
population
Asperger's syndrome: seven times as many people as classic autism; average to higher iq
Pervasive Developmental Disorder (PDD)
Classic Autism and Kanner Autism
- Two-thirds of classic autism: severely to mildly handicapped in cognition and intellect
- Classic Autism: four times more common in boys than in girls
Causes of Autism
● Unknown Theories
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○ Postnatal environment: allergies, and exposure of children to drugs, vaccines,
infection, certain foods
○ Lack of vit D
○ Refrigerator mother
● Valid Theories
○ Genetic Factors: the most significant cause
○ Prenatal environment: age in either parent (m40+, f40+, m30); diabetes,
bleeding, and use of psychiatric drugs in the mother during pregnancy
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● There's no medication to cure autism spectrum disorder, but some some medication
can help manage related symptoms like irritability, anxiety, hyperactivity, and
aggression
● ABA- develop new skills, improve communication, reduce challenging behavior, and
enhance social interactions
● Son-Rise- a child centered, home-based therapy
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