Systemic Zygomycosis (Mucormycosis)
An acute and rapidly developing, less commonly chronic,
infection of debilitated patients. Depending on the portal of
entry, the disease involves the rhino-facial-cranial area, lungs,
gastrointestinal tract, skin or less commonly other organ
systems. The infecting fungi have a predilection for invading
vessels of the arterial system, causing embolization and
subsequent necrosis of surrounding tissue. A suppurative,
pyrogenic reaction is elicited; granuloma formation is not
frequently encountered.
Distribution: World-wide.
Aetiological Agents: Cosmopolitan members of the Mucorales,
including species of Rhizopus, Mucor, Rhizomucor Absidia,
Cunninghamella, Saksenaea and Mortierella.
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