Nature

Genetics articles from across Nature Portfolio

Genetics is the branch of science concerned with genes, heredity, and variation in living organisms. It seeks to understand the process of trait inheritance from parents to offspring, including the molecular structure and function of genes, gene behaviour in the context of a cell or organism (e.g. dominance and epigenetics), gene distribution, and variation and change in populations.

Featured

SBRR1-R variant regulates sheath blight resistance in rice

Rice sheath blight is a major fungal disease caused by the necrotrophic pathogen Rhizoctonia solani. We identified a natural SBRR1-R allele that is activated by the bHLH57 transcription factor, leading to increased expression of chitinase antifungal protein genes that confer resistance to sheath blight.

News & Views04 Aug 2025 Nature Genetics
P: 1-2
G-quadruplexes define promoter identity in mammals

We show that alternative DNA structures, called G-quadruplexes, behave as elements of eukaryotic promoters. Our data suggest that they function to support intrinsic nucleosome exclusion and to facilitate transcriptional pause release by RNA polymerase II.

News & Views01 Aug 2025 Nature Genetics
P: 1-2
Phosphorylation powers plant Polycomb

A ubiquitous protein kinase phosphorylates and stabilizes a key epigenetic effector in Arabidopsis, potentially contributing to mechanisms in plants for timing the duration of winter.
- Christos N. Velanis
- Justin Goodrich
News & Views01 Aug 2025 Nature Plants
P: 1-2

Related Subjects

Latest Research and Reviews

LMF1 frameshift deletion in Franches-Montagnes horses with hypertriglyceridemia-induced pancreatitis
- Michaela Drögemüller
- Nathalie Fouché
- Tosso Leeb
ResearchOpen Access06 Aug 2025 Scientific Reports
Volume: 15, P: 28667
A chromosome-level genome assembly of Electrophorus voltai, a species of electric eel
- Yuanyuan Wang
- Yi Liu
- Xidong Mu
ResearchOpen Access06 Aug 2025 Scientific Data
Volume: 12, P: 1367
Local genetic sex differences in quantitative traits

Analysing 157 traits, this study finds widespread local genetic sex differences masked at the genome-wide level. Using LAVA, it tests for sex-specific heritability, genetic correlation, and effect size equality, revealing sex-dimorphic loci.
- Emil Uffelmann
- Christiaan de Leeuw
- Danielle Posthuma
ResearchOpen Access06 Aug 2025 Nature Communications
Volume: 16, P: 7232
Epigenome-wide association study of BMI and waist-to-hip ratio and their associations with dietary patterns in Korean adults
- Jangho Lee
- Hyo-Kyoung Choi
- Jae-Ho Park
ResearchOpen Access06 Aug 2025 Scientific Reports
Volume: 15, P: 28681
Comprehensive identification of the PEBP gene family in Vicia faba highlighting VfTFL1a variation and phenotypic insights into determinate growth
- Hannah Ohm
- Umer Mahmood
- Per Hofvander
ResearchOpen Access06 Aug 2025 Scientific Reports
Volume: 15, P: 28687
The hidden risks of CRISPR/Cas: structural variations and genome integrity

CRISPR technologies hold vast potential for therapeutic gene editing, however large structural variations often arise, posing an underappreciated safety concern. Here, the authors review emerging evidence of aberrant chromosomal abnormalities and discuss strategies to improve safety outcomes.
- Clotilde Aussel
- Toni Cathomen
- Carla Fuster-García
ReviewsOpen Access05 Aug 2025 Nature Communications
Volume: 16, P: 7208

All Research & Reviews

News and Comment

Breed giant prawns to withstand disease and climate change
- Fengbo Li
- Qiang Gao
Correspondence05 Aug 2025 Nature
Volume: 644, P: 41
In vivo engineering broadens CAR-T cell therapy use
- M. Teresa Villanueva
Research Highlights05 Aug 2025 Nature Reviews Drug Discovery
Unlocking yellow rust resistance
- Jun Lyu
Research Highlights05 Aug 2025 Nature Plants
P: 1
Big data for classifying ASD
- Shari Wiseman
Research Highlights04 Aug 2025 Nature Neuroscience
Volume: 28, P: 1577
SBRR1-R variant regulates sheath blight resistance in rice

Rice sheath blight is a major fungal disease caused by the necrotrophic pathogen Rhizoctonia solani. We identified a natural SBRR1-R allele that is activated by the bHLH57 transcription factor, leading to increased expression of chitinase antifungal protein genes that confer resistance to sheath blight.

News & Views04 Aug 2025 Nature Genetics
P: 1-2
This company claimed to ‘de-extinct’ dire wolves. Then the fighting started.

Colossal’s bold announcements have drawn criticism from many scientists, but the billion-dollar firm is not backing down.
- Ewen Callaway
News04 Aug 2025 Nature
Volume: 644, P: 21-23

All News & Comment

Search

Advanced search

Quick links