Advances in neurodegenerative diseases

This Collection supports and amplifies research related to SDG 3 - Ensure healthy lives and promote well-being for all at all ages.

Neurodegenerative diseases encompass a range of disorders characterized by the progressive degeneration of the nervous system, affecting millions of individuals globally. Conditions such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and multiple sclerosis are among the most prevalent and debilitating. These diseases not only impact the quality of life of affected individuals but also place a significant burden on healthcare systems. Understanding the underlying mechanisms, identifying biomarkers for early diagnosis, and developing effective therapies are crucial for improving patient outcomes and guiding clinical care. The importance of studying these conditions is underscored by the need for innovative approaches that integrate clinical, preclinical, and translational research.

Current research in neurodegenerative diseases is multifaceted, focusing on diverse areas such as disease pathophysiology, the role of genetics, the impact of environmental factors, and the integration of epidemiological studies. Advances in imaging techniques have enhanced our ability to visualize disease progression, while the identification of potential biomarkers holds promise for early diagnostic and prognostic assessments. Additionally, the application of machine learning approaches is revolutionizing data analysis, enhancing our understanding of disease mechanisms, and aiding in more personalized care. Therapeutic strategies, including pharmacological interventions and lifestyle modifications, are under investigation for their potential to alter disease trajectories. This Collection aims to bring together research from various domains related to neurodegenerative conditions, encompassing novel insights into disease pathophysiology, diagnostics, therapeutic developments, and care strategies.

We welcome the submission of all papers relevant to advances in neurodegenerative disease. This is a joint Collection across Nature Communications, Nature Neuroscience, Communications Medicine, Communications Biology, and Scientific Reports. We encourage authors to choose which journal to submit to according to their own preference. However, before any decision is taken, the relevant journal webpages should be checked to ensure the submission is within the journal’s scope. Each journal will apply its standard editorial criteria for scope and advance. Where submissions are more suitable for another participating journal, editors will recommend a transfer to a more appropriate alternative journal. Seamless transfers within the Nature Portfolio help ensure a smooth and timely experience for all authors. Note that Nature Communications and Scientific Reports will only consider original research Articles.