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| Open AccessGifting future scientists the past through well-preserved specimens of modern microbial ecosystems
Historical specimens have enabled transformative insights across kingdoms and ecosystems with new technologies, yet microbes remain largely overlooked in preservation efforts. As we recognize microbial communities as fundamental drivers of planetary health, comprehensive microbial archiving becomes an urgent intergenerational responsibility.
- A. Murat Eren
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Article
| Open AccessScientific literature on carbon dioxide removal revealed as much larger through AI-enhanced systematic mapping
This study used AI to map ~29,000 CDR studies—3–4 times more than expected—showing rapid but uneven growth. The map supports stronger evidence synthesis for climate goals and the IPCC. #CDR
- Sarah Lück
- , Max Callaghan
- & Jan C. Minx
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Article
| Open AccessGlobal wood fuel production estimates and implications
With over 2,000 newly identified data points, this study estimates 2,525 million m3 of wood fuel removals globally in 2019, approximately 30% higher than previously understood. Global production of wood charcoal is estimated at 70.5 million tonnes, approximately 50% higher than previous values.
- E. Ashley Steel
- , Oliver Stoner
- & Leonardo R. Souza
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Article
| Open AccessThe gender gap in scholarly self-promotion on social media
The study shows a significant gender gap in scholarly self-promotion on Twitter, finding that women are about 28% less likely to promote their own academic papers compared to men, a disparity which is even more pronounced among highly productive women at prestigious institutions. Women’s self-promotion efforts tend to yield fewer overall mentions and visibility online compared to men, highlighting systematic gender biases in digital scholarly communication.
- Hao Peng
- , Misha Teplitskiy
- & Emőke-Ágnes Horvát
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Matters Arising
| Open AccessReply to “Proactive measures help shape the EU candidate list of substances of very high concern”
- Jessica Coria
- , Erik Kristiansson
- & Mikael Gustavsson
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Perspective
| Open AccessWhere and how to house big data on small fragments
In the coming years, crystallographic fragment-screening campaigns will deliver massive amounts of data and challenge existing practices and resources. In the article, options are explored for how best to preserve these data for the community to support further research and developments.
- Daniel A. Erlanson
- , Stephen K. Burley
- & Manfred S. Weiss
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Article
| Open AccessThe dynamics of leadership and success in software development teams
Understanding how team dynamics impact performance in collaborative environments remains an open question. Here, authors use fine-grained activity data from software projects to characterize team evolution, showing how team-level changes unfold and how leadership change links to greater success.
- Lorenzo Betti
- , Luca Gallo
- & Federico Battiston
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Perspective
| Open AccessScience acceleration and accessibility with self-driving labs
Collaborative self-diving research is crucial to research acceleration amidst ever more complex problems. Here, authors identify the key challenges to the dual cultivation of centralised self-driving user facilities and networks of self-driving labs.
- Richard B. Canty
- , Jeffrey A. Bennett
- & Milad Abolhasani
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Perspective
| Open AccessThe Sex Inclusive Research Framework to address sex bias in preclinical research proposals
In preclinical research, there is a persistent sex bias where research is conducted with a single sex. Here, the authors present a Sex Inclusive Research Framework that provides a traffic light classification of research proposals to facilitate robust assessment and promote equitable sex inclusion
- Natasha A. Karp
- , Manuel Berdoy
- & Lucy Whitfield
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Article
| Open AccessSubnational variations in the quality of household survey data in sub-Saharan Africa
Household survey data is vital to health and development. The study describes and maps data quality in 35 African countries, finding that data quality varies and worsens with distance from towns, indicating a need for investment in data collection.
- Valentin Seidler
- , Edson C. Utazi
- & Patrick Webb
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Article
| Open AccessAnion-mediated approach to overcome oxidation in ether electrolytes for high-voltage sodium-ion batteries
Use of ether-based electrolytes in Na-ion batteries is challenged with oxidation at high voltages. Here, authors report passivation of vulnerable ether solvents, enabling cathode electrolyte interphase enriched with NaF and NaNxOy and elevating the oxidation resistance of the electrolyte to 4.8 V.
- Xingyu Wang
- , Qi Fan
- & Hui Xia
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Article
| Open AccessStructure, motion, and multiscale search of traveling networks
Complex networks are relevant to wide range of areas, from biology to social sciences and economics, however the aspect that networks can move through space has not been elaborated. The authors propose a concept of traveling networks that can dynamically restructure themselves in space and perform search tasks.
- Nate J. Cira
- , Morgan L. Paull
- & Ingmar H. Riedel-Kruse
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Article
| Open AccessEvent-driven figure-ground organisation model for the humanoid robot iCub
Inspired by the primate visual system, this work implements an event-driven, bio-inspired architecture for figure-ground segmentation on the neuromorphic robot iCub, bridging neuromorphic algorithms and software. Its performance is benchmarked on the Berkeley Segmentation Data Set and validated in real-world scenarios.
- Giulia D’Angelo
- , Simone Voto
- & Chiara Bartolozzi
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Comment
| Open AccessPatient and public involvement and engagement to improve impact on antimicrobial resistance
A step change is required in citizen awareness of antimicrobial resistance (AMR). The authors propose we go further still, directly engaging and involving patients and public in scoping, testing and scaling solutions to this global health crisis.
- Emily Scott-Dearing
- , Vanessa Carter
- & Ara Darzi
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Article
| Open AccessBiomass carbon emissions from nickel mining have significant implications for climate action
Decisions on where to source nickel for use in low-carbon technologies must consider the biomass losses caused by mining. This study found that, in many cases, these unaccounted emissions were significant relative to other Scope 1 and Scope 2 emissions from nickel extraction and processing.
- Evelyn M. Mervine
- , Rick K. Valenta
- & Laura J. Sonter
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Article
| Open AccessContributions of countries without a carbon neutrality target to limit global warming
This study examines contributions of non-carbon neutrality countries to climate mitigation through BECCS. Cultivating switchgrass in these countries can remove up to 19.9 PgC of CO2, leading to net cooling despite biophysical warming effects.
- Jiaxin Zhou
- , Wei Li
- & Xiaomeng Huang
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Comment
| Open AccessA cross-disciplinary research framework at institution level and beyond
Rethinking and restructuring cross-disciplinary research requires innovative models and the Institute for Cross-Disciplinary Physics and Complex Systems (IFISC) stands as a powerful example. Since its creation, IFISC has grown fourfold, now hosting 90 researchers from 15 different countries. Its unique structure fosters collaborations and a shared sense of belonging, built on a common foundation in complex systems. By bridging diverse disciplines and providing cutting-edge training, IFISC is shaping the next generation of researchers while offering a blueprint for how to reorganize research resources to foster cross-disciplinary research at institution levels and beyond.
- Apostolos Argyris
- , Emilio Hernández-García
- & Maxi San Miguel
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Comment
| Open AccessNew methods for deprecating artificial intelligence systems will preserve history and facilitate research
AI developers and policy makers need to devise methods of commercial model deprecation that balance developers’ reasonable interest in restricting access to outdated models with the value of preserving technological developments and enabling ongoing scientific research across versions.
- Tim Johnson
- & Nick Obradovich
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Perspective
| Open AccessData sharing ethics toolkit: The Human Cell Atlas
The human cell atlas (HCA) is intended as an exhaustive guidebook of human cell types and their properties. Here Kirby et al. outline how the HCA Ethics Working Group is working to build a solid foundation to address the complexities of data collection and sharing.
- Emily Kirby
- , Alexander Bernier
- & Bartha M. Knoppers
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Perspective
| Open AccessThe commitment of the human cell atlas to humanity
The Human Cell Atlas (HCA) aims to characterize cells from diverse individuals across the globe to better understand human biology. Here, the authors lay out principles and action items that have been adopted to affirm HCA’s commitment to equity so that the atlas is beneficial to all of humanity.
- Ido Amit
- , Kristin Ardlie
- & Xiaowei Zhuang
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Comment
| Open AccessSnakebite envenoming in Africa remains widely neglected and demands multidisciplinary attention
Snakebite envenoming causes a significant public health burden in Africa. In this Comment, the authors describe the limitations of current snakebite control measures and emphasise the need for more funding to reduce future harm.
- Philipp Berg
- , Francois Theart
- & Lise-Bethy Mavoungou
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Perspective
| Open AccessMapping bacterial extracellular vesicle research: insights, best practices and knowledge gaps
Bacterial extracellular vesicles are rapidly gaining attention in biomarker discovery and therapeutic innovation. Here, the authors map current BEV research practices, highlight knowledge gaps and best practices to ensure advances in BEV research and accelerate BEV applications.
- Nele De Langhe
- , Sofie Van Dorpe
- & An Hendrix
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Comment
| Open AccessTrainees’ perspectives and recommendations for catalyzing the next generation of NeuroAI researchers
New developing area of NeuroAI at the intersection of neuroscience and artificial intelligence has many open challenges, one of which is training the new generation of experts. In this Comment, the authors provide resources and outline training needs and recommendations for junior researchers working across artificial intelligence and neuroscience.
- Andrea I. Luppi
- , Jascha Achterberg
- & Helena M. Gellersen
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Article
| Open AccessCurbing household food waste and associated climate change impacts in an ageing society
Given Japan’s aging population, this study examines household food waste and life cycle greenhouse gas emissions for the six age brackets of Japanese households. Older households have higher food waste emissions than younger households.
- Yosuke Shigetomi
- , Asuka Ishigami
- & Andrew Chapman
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Comment
| Open AccessThree foci at the science-policy interface for systemic Sustainable Development Goal acceleration
The integrated and indivisible nature of the SDGs is facing implementation challenges due to the silo approaches. We present the three interconnected foci (SDG interactions, modeling, and tools) at the science-policy interface to address these challenges. Accounting for them will support accelerated SDG progress, operationalizing the integration and indivisibility principles.
- Prajal Pradhan
- , Nina Weitz
- & Caroline Zimm
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Comment
| Open AccessHarmonize rules for digital sequence information benefit-sharing across UN frameworks
As multiple UN fora develop parallel rules for sharing benefits from digital sequence information, we urge better coordination. International policymakers should focus on harmonizing new benefit-sharing rules to ensure open access to data, database interoperability, and better benefit sharing outcomes.
- Scarlett Sett
- , W. John Kress
- & Amber Hartman Scholz
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Matters Arising
| Open AccessOn the Author Correction to “Magnetic field screening in hydride superconductors”
- J. E. Hirsch
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Article
| Open AccessENCORE: a practical implementation to improve reproducibility and transparency of computational research
Reproducibility of computational research remains challenging. Here, authors present ENCORE, an approach to enhance reproducibility. The most significant challenge to the routine adoption of approaches like ENCORE is the lack of incentives for researchers to dedicate sufficient time and effort to ensure reproducibility.
- Antoine H. C. van Kampen
- , Utkarsh Mahamune
- & Perry D. Moerland
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Article
| Open AccessThe global geography of artificial intelligence in life science research
AI promises to transform medicine, but geographic concentration may hinder its equitable application. Here, authors map a global atlas of medical AI research and show that greater integration of global expertize could help AI deliver on its promise.
- Leo Schmallenbach
- , Till W. Bärnighausen
- & Marc J. Lerchenmueller
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Article
| Open AccessWhat is holding back cyanobacterial research and applications? A survey of the cyanobacterial research community
Cyanobacteria have been the subject of intense basic research, but translation towards industrial applications remains limited. Here, Schmelling and Bross conduct a survey among researchers in the cyanobacterial community, as well as a literature analysis, to highlight potential strategies to enhance cyanobacterial research and accelerate the development of industrial applications.
- Nicolas M. Schmelling
- & Moritz Bross
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Article
| Open AccessA frugal CRISPR kit for equitable and accessible education in gene editing and synthetic biology
Equitable and accessible education in life sciences, bioengineering, and synthetic biology is crucial for training the next generation of scientists. Here the authors present the CRISPRkit, a cost-effective educational tool that enables high school students to perform CRISPR experiments affordably and safely without prior experience, using smartphone-based quantification and an automated algorithm for data analysis.
- Marvin Collins
- , Matthew B. Lau
- & Lei S. Qi
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Editorial
| Open AccessSimplifying data and code sharing
Data is the bedrock of scientific progress. At Nature Communications we have been making it easier for authors to share their source data by integrating both data and code sharing capabilities into our manuscript tracking system.
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Article
| Open AccesstracerDB: a crowdsourced fluorescent tracer database for target engagement analysis
Tracers are fluorescent protein ligands required for various displacement assays. Here, the authors announce a curated database named tracerDB, which will make essential tracer data, contributed by the worldwide research community, easily available and searchable.
- Johannes Dopfer
- , James D. Vasta
- & Martin P. Schwalm
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Perspective
| Open AccessA data science roadmap for open science organizations engaged in early-stage drug discovery
Artificial intelligence is greatly accelerating research in drug discovery, but its development is still hindered by the lack of available data. Here the authors present data management and data science recommendations to help reach AI’s potential in the field.
- Kristina Edfeldt
- , Aled M. Edwards
- & Matthieu Schapira
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Perspective
| Open AccessDeconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists
Developing biotechnologies to address society’s challenges requires integrating concepts across disciplines, posing challenges to educating students with diverse expertise. In this Perspective the authors create a framework for synthetic biology training that deconstructs biotechnologies across spatial scales.
- Ashty S. Karim
- , Dylan M. Brown
- & Julius B. Lucks
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Article
| Open AccessUnequal distributions of crowdsourced weather data in England and Wales
Crowdsourced personal weather data are sought to cope with weather data scarcity. But, in England and Wales, more deprived areas are less covered. This limits the potential for climate adaptation of communities living in these environments.
- Oscar Brousse
- , Charles H. Simpson
- & Clare Heaviside
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Comment
| Open AccessBiological horizons: pioneering open science in the cosmos
- Sylvain V. Costes
- , Chelle L. Gentemann
- & Lisa A. Carnell
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Comment
| Open AccessAbout the International Asteroid Warning Network (IAWN) and the Space Mission Planning Advisory Group (SMPAG)
Atmospheric entry of asteroids or comets can cause significant damage to Earth. Two international bodies, the International Asteroid Warning Network (IAWN), and the Space Mission Planning Advisory Group (SMPAG) are working on dealing with potential threats.
- Detlef V. Koschny
- , Kelly E. Fast
- & Romana Kofler
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Article
| Open AccessFinancial markets value skillful forecasts of seasonal climate
Traders of financial options bet that firms’ stock prices will be affected by forecasts of seasonal climate produced by the U.S. National Oceanic and Atmospheric Administration. Firms are exposed throughout the economy, and traders spend more to hedge the news from more skillful forecasts
- Derek Lemoine
- & Sarah Kapnick
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Article
| Open AccessIntegrating spin-dependent emission and dielectric switching in FeII catenated metal-organic frameworks
Incorporating spin crossover motifs into mechanically interlocked molecules offers various switchable properties. Here, the authors report two FeII catenated metal-organic frameworks that exhibit spin dependent luminescence and dielectric switching.
- Xue-Ru Wu
- , Shu-Qi Wu
- & Hui-Zhong Kou
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Comment
| Open AccessImpression management in sex and gender neuroscience research reporting: the MAGIC guidelines
Here, the authors discuss guidelines to avoid miscommunication of findings in research into sex and gender-based differences in the brain.
- Gina Rippon
- , Katy Losse
- & Simon White
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Comment
| Open AccessChallenges and ways forward for sustainable weather and climate services in Africa
Sustainability of African weather and climate information can only be ensured by investing in improved scientific understanding, observational data, and model capability. These requirements must be underpinned by capacity development, knowledge management; and partnerships of co-production, communication and coordination.
- Benjamin Lamptey
- , Salah SAHABI ABED
- & Erik W. Kolstad
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Article
| Open AccessA framework for evaluating clinical artificial intelligence systems without ground-truth annotations
Estimating the performance of clinical AI systems on data in the wild is complicated by distribution shift and the absence of ground-truth annotations. Here, we introduce SUDO, a framework for more reliably evaluating AI systems on data in the wild.
- Dani Kiyasseh
- , Aaron Cohen
- & Nicholas Altieri
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Comment
| Open AccessThe bioethics of skeletal anatomy collections from India
Millions of skeletal remains from South Asia were exported in red markets (the underground economy of human tissues/organs) to educational institutions globally for over a century. It is time to recognize the personhood of the people who were systematically made into anatomical objects and acknowledge the scientific racism in creating and continuing to use them.
- Sabrina C. Agarwal
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Article
| Open AccessExtracting accurate materials data from research papers with conversational language models and prompt engineering
Efficient data extraction from research papers accelerates science and engineering. Here, the authors develop an automated approach which uses conversational large language models to achieve high precision and recall in extracting materials data.
- Maciej P. Polak
- & Dane Morgan
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Article
| Open AccessOpen-source microscope add-on for structured illumination microscopy
Researchers developed an open-hardware structured illumination microscopy add-on. This affordable upgrade provides super-resolution capabilities for normal optical microscopes. Detailed instructions enable easy reproduction to help democratize advanced microscopy.
- Mélanie T. M. Hannebelle
- , Esther Raeth
- & Georg E. Fantner
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Article
| Open AccessCases of trisomy 21 and trisomy 18 among historic and prehistoric individuals discovered from ancient DNA
Information on the occurrence of aneuploidies in prehistory human populations are rare. Here, from a large screen of ancient human genomes and osteological examination, the authors find genetic evidence for six cases of trisomy 21 (Down syndrome) and one case of trisomy 18 (Edwards syndrome) in historic and prehistoric infants.
- Adam Benjamin Rohrlach
- , Maïté Rivollat
- & Kay Prüfer
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Article
| Open AccessStructured information extraction from scientific text with large language models
Extracting scientific data from published research is a complex task required specialised tools. Here the authors present a scheme based on large language models to automatise the retrieval of information from text in a flexible and accessible manner.
- John Dagdelen
- , Alexander Dunn
- & Anubhav Jain
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Article
| Open AccessDelayed increase in stone tool cutting-edge productivity at the Middle-Upper Paleolithic transition in southern Jordan
Lithic cutting-edge productivity is a way of quantifying prehistoric human technological evolution. Here, the authors examine the Middle-to-Upper Paleolithic transition across eight assemblages in the eastern Mediterranean, finding the transition to be later than expected and associated with bladelet technology development.
- Seiji Kadowaki
- , Joe Yuichiro Wakano
- & Sate Massadeh