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The Emergence of Up and Down States in Cortical Networks

Figure 4

Effect of Synaptic Plasticity on Up–Down State Dynamics

(A) Effect of increasing wT, which is equivalent to the LTP effect. The effect of LTP is obtained by increasing the total synaptic connections wT to a value of 15. The effect is similar to a depolarization injection current.

(B) Effect of LTD on Up–Down state dynamics. The effect of LTD is obtained by decreasing the total synaptic connections wT to a value of 11. The effect is similar to hyperpolarizing the ensemble of neurons.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.0020023.g004