Constrained Allocation Flux Balance Analysis
Fig 4
Average CAFBA solutions (heterogeneous case) for six different glycolytic carbon sources.
Each plot shows a different average flux, specifically: (A) Acetate secretion, (B) TCA cycle flux (represented by αKG dehydrogenase), (C) Glyoxylate shunt flux (malate synthase), (D) CO2 secretion, (E) ED pathway flux, (6-phosphogluconate dehydratase). Each point represents the average over 500 solutions obtained with the same wC ≥ 0 and 〈w〉 = 8.8 × 10−4 gh/mmol. Vertical lines at λac = 0.79/h are shown for clarity. In panel (A), acetate secretion can be approximated, for λ ≥ λac, with a straight line vac = s × (λ−λac) with s = 45 mmol/gDW.