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Global Regulation of Nucleotide Biosynthetic Genes by c-Myc

Figure 7

Mycophenolic acid (MPA) induces apoptosis in P493-6 and Ramos cells.

Cells with designated treatments were subjected to annexin V staining with 7-AAD and flow cytometry after 48 hours. Cells in the lower right quadrant, which are annexin-positive but 7-AAD-negative, represent the apoptotic population. Necrotic or late apoptotic cells are 7-AAD-positive. The number indicates the percentage of the cells in each quadrant.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0002722.g007