Localization of Canine Brachycephaly Using an Across Breed Mapping Approach
Figure 3
Across breed genome-wide association for brachycephaly.
A. -log 10 of the permutated (100,000) p values (y axis) for genome wide association for brachycephaly across dog breeds are plotted by chromosome (x axis). Raw p values as well as the permutated p value for the most significant associations are shown near the peak. B. Chromosome-wide association for SNPs (black) and haplotypes (grey) defined by the four gamete rule were performed using Haploview using 50000 permutations. -log10 of permuted p values (y axis) are plotted against position on the chromosome in Mb (x axis).