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Over-Expression of PDGFR-β Promotes PDGF-Induced Proliferation, Migration, and Angiogenesis of EPCs through PI3K/Akt Signaling Pathway

Figure 9

Representative photos of PDGF-BB-induced EPC migration by PI3K/Akt pathway.

Cells in the control group (A) and the pEGFP-N2-PDGFR-β group (B) were without pretreatment or pretreated with AG1295, LY294002, or sc-221226 for 1 h and then treated with 20 ng/mL PDGF-BB (for the control cells) or 80 ng/mL PDGF-BB (for the pEGFP-N2-PDGFR-β cells). Scale bar = 100 µm.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0030503.g009