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The Yin and Yang of Yeast Transcription: Elements of a Global Feedback System between Metabolism and Chromatin

Figure 5

Statistical DNA profiles (SDP) of nucleosome occupancy, Isw2(K215R) ChIP, Rap1p DIP, Rsc8p ChIP & transcriptome tiling array datasets.

SDP were constructed as desribed for Figure 4. Figure 1C provides a color legend. Only results for consensus clusters are shown here, see Figure S11 for background clusters. Nucleosome occupancy data from 5A: tiling array dataset in 4 bp resolution [36]; 5B: Isw2(K215R) ChIP-tiling array data in 5 bp resolution [40]. 5D: transcriptome tiling array data in 8 bp resolution [68] on the sense strand; 5E: same as 5D but for the signal from the antisense strand. 5C & 5F: data are from [41] with resolution & SDP bin size: 32 bp; 5C: Rsc8-TAP ChIP-chip data in wildtype cells. 5F: Rap1 DIP-chip data (in vitro “DNA immunoprecipitation-chip” of genomic DNA by Rap1p).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0037906.g005