The bHLH Repressor Deadpan Regulates the Self-renewal and Specification of Drosophila Larval Neural Stem Cells Independently of Notch
Figure 6
Ectopic NBs persist in adult brains after Dpn is over-expressed. (
A–A’) Wild type adult brains do not have any NBs, as indicated by the absence of Mira+ cells (A’). (B–B’) Ectopic/over-expression of Dpn in the type II NB lineages using insc-Gal4 ase-Gal80 leads to numerous Ase- type II NBs and immature INPs in adult brains. (C–C’) Ectopic/over-expression of Dpn in type I NBs using ase-Gal4 results in ectopic Ase+ type I NBs in adult brains. Mira staining (blue) labels NBs. Insets in (B) and (C) show enlarged views of the highlighted areas.