ROS Stress Resets Circadian Clocks to Coordinate Pro-Survival Signals
Figure 5
Microarray analysis of gene regulation by cOS-pulse.
Microarray analysis using workflow for one-color Mouse GE 4x44K v2 (Agilent Technologies; harboring 39430 mouse transcripts) was performed to identify up-regulated genes during the early stage (4h post cOS-pulse) immediate surge of Per2-Luc and late stage (20h and 32h), as compared vs. the control (only medium-change). (A) The graph shows the total number of the (≧ 2-fold) up-regulated genes at the each time point. (B) The graph shows the total number of the circadian circadian-fluctuated (≧ 2-fold) genes at the each time point. (C) The graph shows the total number of the up-regulated annotation clusters (ACs) at the each time point.