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SOX9 shapes hepatic granuloma architecture in schistosomiasis infection
Representative Picrosirius Red staining of fibrillar collagen in hepatic granulomas from (LEFT) wild-type and (RIGHT) SOX9-deficient mice, revealing the essential role of SOX9 in organising a fibrotic barrier around Schistosoma mansoni eggs. In the absence of SOX9, granulomas are disorganised and poorly contained, leading to diffuse liver injury. Su et al. 2025
Image Credit: Karen Piper Hanley and Elliot Jokl