AI Language Models in Health Care

Large Language Models for Automating Clinical Trial Criteria Conversion to Observational Medical Outcomes Partnership Common Data Model Queries: Validation and Evaluation Study

Kye Hwa Lee, Sujung Jang, Grace Juyun Kim, Sukyoung Park, Doeun Kim, Oh Jin Kwon, Jae-Ho Lee, Young-Hak Kim

JMIR Med Inform 2025 (Oct 16); 13:e71252

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Explainable AI-Driven Analysis of Radiology Reports Using Text and Image Data: Experimental Study

Muhammad Tayyab Zamir, Safir Ullah Khan, Alexander Gelbukh, Edgardo Manuel Felipe Riverón, Irina Gelbukh

JMIR Form Res 2025 (Oct 14); 9:e77482

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Performance of Large Language Models in Diagnosing Rare Hematologic Diseases and the Impact of Their Diagnostic Outputs on Physicians: Combined Retrospective and Prospective Study

Hongbin Yu, Tian Chen, Xin Zhang, Yunfan Yang, Qinyu Liu, Chenlu Yang, Kai Shen, He Li, Wenjiao Tang, Xushu Zhong, Xiao Shuai, Xinmei Yu, Yi Liao, Chiyi Wang, Huanling Zhu, Yu Wu

J Med Internet Res 2025 (Oct 09); 27:e77334

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Comparative Diagnostic Accuracy of AI-Assisted Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography Versus Structural Magnetic Resonance Imaging in Alzheimer Disease: Systematic Review and Meta-Analysis

Bingbing Wang, Tailiang Zhao, Rongrong Ma, Xiaochuan Huo, Xiaoxiao Xiong, Minjie Wu, Yuran Wang, Liu Liu, Zhijiang Zhuang, Bin Wang, Jixin Shou

JMIR Aging 2025 (Oct 08); 8:e76981

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A Vision-Language–Guided Multimodal Fusion Network for Glottic Carcinoma Early Diagnosis: Model Development and Validation Study

Zhaohui Jin, Yi Shuai, Yun Li, Mianmian Chen, Yumeng Liu, Wenbin Lei, Xiaomao Fan

JMIR Med Inform 2025 (Oct 08); 13:e74902

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Large Language Model–Enhanced Drug Repositioning Knowledge Extraction via Long Chain-of-Thought: Development and Evaluation Study

Hongyu Kang, Jiao Li, Li Hou, Xiaowei Xu, Si Zheng, Qin Li

JMIR Med Inform 2025 (Oct 07); 13:e77837

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Assessing the Capability of Large Language Models for Navigation of the Australian Health Care System: Comparative Study

Joshua Simmich, Megan Heather Ross, Trevor Glen Russell

JMIR AI 2025 (Oct 07); 4:e76203

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Taxonomy Portraits: Deciphering the Hierarchical Relationships of Medical Large Language Models

Radha Nagarajan, Vanessa Klotzman, Midori Kondo, Sandip Godambe, Adam Gold, John Henderson, Steven Martel

JMIR Med Inform 2025 (Oct 07); 13:e72918

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From Context to Care: Rethinking Stigma Detection in Clinical Language Models

Shefali Haldar, Oliver Bear Don't Walk IV, Sadia Akter

JMIR Med Inform 2025 (Oct 02); 13:e82484

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Using Large Language Models for Chronic Disease Management Tasks: Scoping Review

Henry Mukalazi Serugunda, Ouyang Jianquan, Hasifah Kasujja Namatovu, Paul Ssemaluulu, Nasser Kimbugwe, Christopher Garimoi Orach, Peter Waiswa

JMIR Med Inform 2025 (Sep 29); 13:e66905

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Author’s Reply: "Data Contamination in AI Evaluation"

ChulHyoung Park, Min Ho An, Gyubeom Hwang, Rae Woong Park, Juho An

JMIR Med Inform 2025 (Sep 29); 13:e82057

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Data Contamination in AI Evaluation

Alaeddin Acar

JMIR Med Inform 2025 (Sep 29); 13:e80987

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Using Large Language Models to Assess the Consistency of Randomized Controlled Trials on AI Interventions With CONSORT-AI: Cross-Sectional Survey

Xufei Luo, Zeming Li, Zhenhua Yang, Bingyi Wang, Yanfang Ma, Fengxian Chen, Qi Wang, Long Ge, James Zou, Lu Zhang, Yaolong Chen, Zhaoxiang Bian

J Med Internet Res 2025 (Sep 26); 27:e72412

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Improving the Reporting Quality of Studies on Information Extraction From Clinical Texts: Protocol for the Development of a Consensus-Based Reporting Guideline

Daniel Reichenpfader, Henning Müller, Kerstin Denecke

JMIR Res Protoc 2025 (Sep 24); 14:e76776

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Critical Limitations in Systematic Reviews of Large Language Models in Health Care

Zvi Weizman

J Med Internet Res 2025 (Sep 24); 27:e81769

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Author's Reply: Critical Limitations in Systematic Reviews of Large Language Models in Health Care

Andre Python, HongYi Li, Jun-Fen Fu

J Med Internet Res 2025 (Sep 24); 27:e82729

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Comparative Diagnostic Performance of a Multimodal Large Language Model Versus a Dedicated Electrocardiogram AI in Detecting Myocardial Infarction From Electrocardiogram Images: Comparative Study

Haemin Lee, Sooyoung Yoo, Joonghee Kim, Youngjin Cho, Dongbum Suh, Keehyuck Lee

JMIR AI 2025 (Sep 17); 4:e75910

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Collecting and Sharing Person-Centered AI Clinical Summaries Across Frailty Services Provided by the National Health Service and Voluntary, Community, and Social Enterprise: Protocol for a Co-Design and Feasibility Study

Kieran Green, Sheena Asthana, Oscar Josue Ponce-Ponte, John Downey, Joanne Watson

JMIR Res Protoc 2025 (Sep 17); 14:e68511

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New Doc on the Block: Scoping Review of AI Systems Delivering Motivational Interviewing for Health Behavior Change

Zev Karve, Jacob Calpey, Christopher Machado, Michelle Knecht, Maria Carmenza Mejia

J Med Internet Res 2025 (Sep 16); 27:e78417

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Viewpoint on the Intersection Among Health Information, Misinformation, and Generative AI Technologies

António Bandeira, Luis Henrique Gonçalves, Felix Holl, Juliet Ugbedeojo Shaibu, Mariana Laranjo Gonçalves, Ronan Payinda, Sagun Paudel, Alessandro Berionni, Young WFPHA, Tina D Purnat, Tim Mackey

JMIR Infodemiology 2025 (Sep 15); 5:e69474

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