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Central Nervous System: Drug of Choices Notes - Kent Andrei Paelma Bsn-2F

The document lists the drug of choice for treating various medical conditions in three main categories: central nervous system conditions, hematological conditions, and cancer. Some of the major drugs listed as first-line treatments include valproate for absence seizures, lamotrigine for focal seizures, morphine for pain management, ferrous sulfate for iron deficiency anemia, tamoxifen for breast cancer, and cisplatin for various cancers.
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0% found this document useful (0 votes)
266 views22 pages

Central Nervous System: Drug of Choices Notes - Kent Andrei Paelma Bsn-2F

The document lists the drug of choice for treating various medical conditions in three main categories: central nervous system conditions, hematological conditions, and cancer. Some of the major drugs listed as first-line treatments include valproate for absence seizures, lamotrigine for focal seizures, morphine for pain management, ferrous sulfate for iron deficiency anemia, tamoxifen for breast cancer, and cisplatin for various cancers.
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Download as PDF, TXT or read online on Scribd
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DRUG OF CHOICES NOTES - Kent Andrei Paelma BSN-2F

CENTRAL NERVOUS SYSTEM


➢ Drug of choice for generalized absent seizure- Ethosuximide and Sodium valproate
➢ Drug of choice for absence (Petit mal) seizures - Valproate
➢ Drug of choice for absence seizures in children - Ethosuximide
➢ Drug of choice for myoclonic seizures in men - Sodium Valproate
➢ Drug of choice for myoclonic seizures in women - Lamotrigine
➢ Drug of choice for focal seizure - Lamotrigine
➢ Drug of choice for generalized tonic-clonic seizures (GTCS) - Lamotrigine
➢ Drug of choice for tonic-clonic seizures - Sodium Valproate
➢ Drug of choice for infantile seizures - ACTH
➢ Drug of choice for rhinorrhea - Cetirizine
➢ Drug of choice for phobias - SSRI's
➢ Drug of choice for reducing preanesthetic anxiety - Lorazepam
➢ Drug of choice for status epilepticus - I. V Lorazepam
➢ Drug of choice for febrile seizures - Diazepam
➢ Drug of choice for partial seizures - Carbamazepine
➢ Drug of choice for attention deficit hyperactivity disorder - Methylphenidate
➢ Drug of choice for Alzheimer's disease - Rivastigmine
➢ Drug of choice for obsessive-compulsive disorder (OCD) - Fluoxetine Drug of choice for
drug-induced parkinsonism - Benzhexol
➢ Drug of choice for parkinsonism - Ropinirole, Pramipexole
➢ Drug of choice for glioma - Nitrosourea
➢ Drug which has pain relief properties without opioid disadvantages - Tramadol
➢ Drug of choice for sedation in patients with severe liver failure - Lorazepam
➢ Drug of choice for maintenance treatment of generalized anxiety disorder - Buspirone
➢ Drug of choice for febrile seizures - Diazepam
➢ Drug of choice for endoscopic and colonoscopy – Midazolam
➢ Drug of choice for cerebral edema - Mannitol
➢ Drug of choice for increased intracranial pressure - Mannitol
➢ Drug of choice for psychomotor seizures - Carbamazepine
➢ Drug of choice for mania - Lithium Carbonate
➢ Drug of choice for Huntington chorea - Tetrabenazine
➢ Drug of choice for Parkinsonism - Ropinirole and Pramipexole
➢ Drug of choice for morning sickness - Hyoscine
➢ Drug of choice for multiple sclerosis - Amitriptyline
➢ Drug of choice for acute attack of migraine - Sumatriptan /Ergotamine
➢ Drug of choice for night terrors - Benzodiazepines
➢ Drug of choice for atypical depression - MAO inhibitors
➢ Drug of choice for hydrocephalus - Glycerol or Acetazolamide
➢ Drug of choice for cluster headache - Sumatriptan
➢ Treatment of choice for cluster headache - High flow 02
➢ Drug of choice for infantile spasm - ACTH
➢ Drug of choice for Huntington chorea - Tetra benzene
➢ Drug of choice for multiple sclerosis - Interferon B
➢ Drug of choice for pulmonary edema - Morphine
➢ Drug of choice generalized anxiety disorders - Diazepam (Benzodiazepines)
➢ Drug of choice for pain in terminal illness - Morphine
➢ Drug of choice for pain of acute myocardial infarction - Morphine
➢ Drug of choice for chronic cancer pain - Morphine
➢ Drug of choice for borderline personality disorder - Buspirone (5 HT partial agonist)
➢ Drug of choice for neonate with respiratory depression due to use of morphine to
control severe labor pain - Naloxone
➢ Drug of choice for sedation in liver failure patients - Lorazepam
➢ Drug of choice for decreasing anxiety in children preoperatively - Antihistaminic
➢ Drug of choice for sedation in patients with porphyria’s - Benzodiazepines
➢ Drug of choice for trigeminal neuralgia - Carbamazepine
➢ Drug of choice for status absence - Benzodiazepines
➢ Drug of choice for convulsion in lidocaine treated patients - Diazepam
➢ Drug of choice for tardive dyskinesia – Diazepam
➢ Drug of choice for hypnosis in elderly - Zolpidem
➢ Drug of choice for diabetic neuropathy - Topiramate
➢ Drug of choice for neuropathic pain - Lamotrigine or Topiramate or Gabapentin
➢ Drug of choice for reducing alcohol craving - Naltrexone
➢ Drug for decreasing relapse of alcoholism - Acamprosate (NMDA receptor antagonist)
or Naltrexone
➢ Drug of choice for alcohol detoxification - Disulfiram
➢ Drug of choice for smoking cessation - Bupropion
➢ Drug of choice for depression in Parkinson disease - SSRI's
➢ Drug of choice for Parkinson disease - Levodopa
➢ Drug of choice for psychosis in Parkinson disease - Clozapine
➢ Drug of choice for depression - SSRI's
➢ Drug of choice for restless leg syndrome - Ropinirole
➢ Drug of choice for violent behaviour - Haloperidol
➢ Drug of choice for psychotic depression - Loxapine
➢ Drug of choice for neutropenia in felty's syndrome – Lithium
➢ Drug of choice for patients with extra pyramidal symptoms (EPS) - Clozapine
➢ Drug of choice for negative symptoms - Clozapine
➢ Drug of choice for treatment resistant schizophrenia - Clozapine
➢ Drug of choice for elderly with schizophrenia - Clozapine
➢ Drug of choice for peripheral neuropathy - Lamotrigine
➢ Drug of choice for bulimia - SSRI's (Eg: Fluoxetine)
➢ Drug of choice for acute mania - Lithium
➢ Drug of choice for serotonin syndrome - Cyproheptadine
➢ Drug of choice for nocturnal enuresis - Desmopressin
➢ Drug of choice for major depression - SSRI's
➢ Drug of choice for heat stroke - Chlorpromazine
➢ Drug of choice for OCD - SSRI's or Clomipramine
➢ Drug of choice for sleep walking - Carbamazepine
➢ Drug of choice for cluster headache - Lithium
➢ Drug of choice for cyclical vomiting - Lithium
➢ Drug of choice for bipolar mood disorder – Lithium
➢ Drug of choice for convulsion in tetanus patients – Diazepam
➢ Drug of choice for delirium caused by ketamine – Diazepam
HEMATOLOGY
✓ Drug of choice for microcytic anemia - Ferrous Sulfate
✓ Drug of choice for iron deficiency anemia in pregnancy - Ferrous sulphate
✓ Drug of choice for warfarin overdose - Vitamin K
✓ Drug of choice for heparin overdose - Protamine sulphate
✓ Drug of choice for hairy cell leukemia - Cladribine
✓ Drug of choice for chronic lymphocytic leukemia - Fludarabine
✓ Drug of choice for chronic myeloid leukemia (CML) - Imatinib
✓ Drug of choice for chemotherapy-induced anemia - Erythropoietin
✓ Drug of choice for anemia due to chronic kidney disease (CKD) - Erythropoietin
✓ Drug of choice for autoimmune hemolytic anemia - Prednisolone
✓ Drug of choice for transient ischemic attack (TIA) - Aspirin
✓ Drug of choice for multiple myeloma - Melphalan
✓ Drug of choice for heparin-induced thrombocytopenia - Argatroban
✓ Drug of choice for chemotherapy-induced leukopenia - Sargramostim
✓ Drug of choice for chemotherapy induced thrombocytopenia - Oprelvekin
✓ First line drugs for multiple myeloma - Prednisolone, Prednisolone,
Cyclophosphamide
✓ Drug of choice for heparin-induced thrombocytopenia - Argatroban
✓ Drug of choice for bleeding due to heparin - Hirudin
✓ Drug of choice for warfarin overdose - Vitamin K
✓ Drug of choice for heparin overdose - Protamine
✓ Thrombolytic agent of choice in acute myocardial infarction - Streptokinase
✓ Drug of choice for arterial fibrillation induced clotting - Warfarin
✓ Drug of choice for prevention of stroke - Aspirin
✓ Drug of choice for prevention of deep vein thrombosis - Low molecular, weight
heparin (LMWH)
✓ Drug of choice for preventing bleeding due to thrombolytic therapy – Epsilion amino
capronic acid
✓ Drug of choice for treatment of deep vein thrombosis – Low molecular, weight heparin
(LMWH)
✓ DOC for pulmonary embolism – Low molecular, weight heparin (LMWH)
✓ DOC for anemia in chronic renal failure – Erythropoietin
ANTICANCER DRUGS

➢ Drug of choice for breast cancer - Tamoxifen


➢ Drug of choice for glioma - Nitrosourea
➢ Drug of choice for colorectal cancer - 5 Fluorouracil
➢ Drug of choice for choriocarcinoma - Methotrexate
➢ Drug of choice for pancreatic carcinoma - Gemcitabine
➢ First line chemotherapy for cervix carcinoma - Cisplatin
➢ Drug of choice for the brain tumor - Lomustine
➢ Drug of choice for prostate carcinoma - Flutamide
➢ Drug of choice for insulinoma - Streptozotocin
➢ Drug of choice for polycythemia vera - Busulphan or Chlorambucil
➢ Drug of choice for carcinoma of endometrium - Progestins
➢ Drug of choice for kaposi sarcome - IF2 alpha
➢ Drug of choice for CLL- Chlorambucilor Fludarabine
➢ Drug of choice for acute myelocytic leukemia - Cytarabine with Mitoxantrone
➢ Drug of choice for wilm's tumor - Vincristine with Danctinomycin
➢ Drug of choice for acute promyeloblastic leukemia - Retinoic acid
➢ Drug of choice for hairy cell leukemia - Cladarabine
➢ Drug of choice for thyroid carcinoma - |-131 with Doxorubicin and cisplatin
➢ Drug of choice for stomach cancer - Fluorouracil with cisplatin
➢ Drug of choice for CML -Imatinib or Busulfan
➢ Drug of choice for acute lymphocytic leukemia (ALL) - Vincristine + Prednisolone +
Mercaptopurine + Cyclophosphamide + Methotrexate
➢ DOC for ovarian cancer – Cisplatin with Paclitaxel
➢ DOC For lung cancer – Cisplatin with Taxane
➢ DOC For malignant melanoma - Dacarbazine
➢ DOC For testicular cancer – Bleomycin + Etoposide + Cisplatin
ANTIMICROBIAL DRUGS

• Drug of choice for gram negative sepsis - Piperacillin with Toberamycin


• Drug of choice for gram positive sepsis - Vancomycin with Gentamicin
• Drug of choice for toxic shock syndrome (Group A strep.) - Penicillin with Clindamycin
• Drug of choice for necrotizing fasciitis (Group A streptococcus) - Penicillin
• Drug of choice for prophylaxis of cardiac lesions in infective endocarditis - Amoxicillin
• Drug of choice for impetigo - Penicillin G
• Drug of choice for meningococcal meningitis - Penicillin G
• Drug of choice for severe falciparum and chloroquine resistant malaria - Quinine
• Drug of choice for enterococcus faecium - Linezolid
• Drug of choice for animal bite - Amoxicillin
• Drug of choice for otitis media - Amoxicillin
• Drug of choice for dirty wound prophylaxis - Cefazolin
• Drug of choice for pneumococcal pneumonia in adults - Amoxicillin
• Drug of choice for typhus fever - Chloramphenicol
• Drug of choice for lice infection - 1% permethrin
• Drug of choice for dental prophylaxis in infective endocarditis - Clarithromycin
• Drug of choice for cellulitis - Oxacillin
• Drug of choice for severe infection in penicillin allergic patient- Vancomycin
• Drug of choice for microspora - Albendazole
• Drug of choice for serious upper urinary tract infections - Aminoglycosides
• Drug of choice for serious upper respiratory infections by atypical pathogens -
Doxycycline
• Drug of choice for endocardial prophylaxis in patients allergic to penicillin - Vancomycin
• Drug of choice for histoplasmosis - Amphotericin B
• Drug of choice for invasive streptococcal infection - Clindamycin
• Drug of choice for dermatitis herpetiformis - Aspirin.
• Drug of choice for cryptoccocus - Fluconazole
• Drug of choice for vulvovaginal candidiasis - Fluconazole
• Drug of choice for pyrazinamide induced hyperuricemia - Aspirin
• Drug of choice for systemic fungal infection - Amphotericin B
• Drug of choice for CMV retinitis - Gancyclovir
• Drug of choice for condyloma accuminata - Podophyline
• Drug of choice for cholera - Doxycycline
• Drug of choice for chlamydiae - Tetracycline (Eg: Doxycycline)
• Drug of choice for tropical sprue - Tetracycline
• Drug of choice for relapsing fever - Tetracycline
• Drug of choice for rocky spotted mountain fever - Tetracycline
• Drug of choice for tick typhus - Tetracycline
• Drug of choice for scrubs typhus - Tetracycline
• Drug of choice for syphilis - Penicillin G
• Drug of choice for toxoplasmosis - Cotrimoxazole
• Drug of choice for legionella - Azithromycin or Levofloxacin
• Drug of choice for lymphogranuloma venereum (LGV) - Azithromycin
• Drug of choice for kala-azar - Sodium Stibogluconate
• Oral drug of choice for kala-azar - Miltefosine
• Drug of choice for plague - Streptomycin
• Drug of choice for brucella - Streptomycin
• Drug of choice for tularemia - Streptomycin
• Drug of choice for rhinoscleroma - Streptomycin
• Drug of choice for actinomycosis - Penicillin-G
• Drug of choice for leprosy - Dapsone.
• The most effective drug against Mycobacterium leprae - Rifampicin
• Drug of choice for herpes zoster - Valaciclovir
• Drug of choice for herpes simplex - Acyclovir
• Drug of choice for influenza - Oseltamivir
• Drug of choice for blood fluke - Praziquantel
• Drug of choice for lung fluke - Praziquantel
• Drug of choice for typhoid (Enteric fever) - 1. V Ceftriaxone
• Drug of choice for leptospirosis - Penicillins
• Drug of choice for Plasmodium vivax - Chloroquine
• Drug of choice for Plasmodium falciparum - Artemisinin combination therapy
(Artesunate + Pyrimethamine + Sulfadoxine)
• Drug of choice for cerebral malaria - Artesunate
• Drug of choice for malaria - Chloroquine
• Drug of choice for chloroquine-resistant malaria - Artemisinin combination therapy
(Artesunate + Pyrimethamine + Sulfadoxine)
• Drug of choice for brucella - Streptomycin with doxycycline
• Drug of choice for candida - Fluconazole
• Drug of choice for aspergillosis - Voriconazole
• Drug of choice for dermatophytosis-Topically (Azole), Systemic (Griseofulvin)
• Drug of choice for Chagas disease - Nifurtimox, Benznidazole
• Drug of choice for dysuria - Phenazopyridine
• Drug of choice for gonorrhea - Procaine Penicillin
• Drug of choice for syphilis - Procaine penicillin
• Drug of choice for rickettsial infection - Tetracycline
• Drug of choice for plague - Tetracycline
• Drug of choice for anthrax - Doxycycline
• Drug of choice for toxoplasmosis - Trimethoprim Sulphamethoxazole
• Drug of choice for Haemophilus influenza type B - Rifampicin
• Drug of choice for prophylaxis of tuberculosis - Isoniazid
• Drug of choice for diarrhea in HIV patient - Octreotide
• Drug of choice for acyclovir-resistant herpes - Foscarnet
• Drug of choice for hepatitis B - Limuvidine
• Drug of choice for hepatitis C - Ribavarine & Interferon 2 alpha
• Drug of choice for lava migrans - Albendazole
• Drug of choice for inflammatory – Sulphasalazine
• Drug of choice for gonococcal urethritis - Azithromycin
• Drug of choice for chancroid - Azithromycin
• Drug of choice for legionellosis - Azithromycin
• Drug of choice for trachoma - Azithromycin
• Drug of choice for inflammed acne - Minocycline
• Drug of choice for cystic acne - Isotretinoin
• Drug of choice for urinary tract infection - Norfloxacin
• Drug of choice for scabies - Permethrin
• Oral drug of choice for scabies - Ivermectin
• Drug of choice for filariasis - Diethyl Carbamazine (DEC)
• Drug of choice for listeria monocytogenes - Ampicillin
• Drug of choice for enterococcus fecalis - Ampicillin
• Drug of choice for toxoplasmosis - Cotrimoxazole
• Drug of choice for toxoplasmosis in pregnancy - Spiramycin
• Drug of choice for schistosomiasis - Praziquantel
• Drug of choice for leishmaniasis - Amphotericin B
• Drug of choice for Aspergillosis - Amphotericin B
• Drug of choice for roundworm (Ascaris) - Albendazole (Anti helminthic agent)
• Drug of choice for pinworm (Enterobius vermicularis) - Albendazole (Anti helminthic
agent)
• Drug of choice for hookworm - Albendazole (Anti helminthic agent)
• Drug of choice for whip worm - Albendazole (Anti helminthic agent)
• Drug of choice for trichinae worm (Trichinella spiralis) - Albendazole (Anti helminthic
agent)
• Drug of choice for guinea worm (Dracunculus medinensis) - Albendazole (Anti
helminthic agent)
• Drug of choice for hydatid disease - Albendazole
• Drug of choice for filarial worm - Ivermectin (Anti helminthic agent)
• Drug of choice for threadworm (Strongyloides stercoralis) - Ivermectin (Anti helminthic
agent)
• Drug of choice for pork tapeworm (Taenia solium) - Praziquantel
• Drug of choice for beef tapeworm (Taenia saginata) – Praziquantel
• Drug of choice for prophylaxis of newborn to TB mother - INH
• Drug of choice for accidental exposure of HIV to health care workers - Zidovudine with
Lamivudine
• Drug of choice for salmonella - Ceftriaxone
• Drug of choice for meningitis - Ceftriaxone
• Drug of choice for gonorrhea - Ceftriaxone
• Drug of choice for resistant pneumococcal infections - Ceftriaxone.
• Second line drug of choice for filariasis - Ivermectin
• Drug of choice for tapeworm infestation - Praziquantel
• Drug of choice for strongyloidiasis (Threadworm) - Ivermectin
• Drug of choice for onchocerciasis (River Blindness) - Ivermectin
• Drug of choice for tetanus - Metronidazole
• Drug of choice for listeria - Ampicillin.
• Second line drug of choice for listeria - SMZ-TMP (Sulphamethoxazole,
Trimethoprim)
• Drug of choice for MRSA - Vancomycin
• Drug of choice for vancomycin - resistant staph aureus (VRSA) - Linezolid
• Drug of choice for neonatal meningitis - Ampicillin + 3rd generation Cephalosporin
• Drug of choice for bacteriosides fragialis - Clindamycin
• Drug of choice for pseudomembranous colitis - Metronidazole
• Drug of choice for amebiasis - Metronidazole
• Drug of choice for trench mouth - Metronidazole
• Drug of choice for bacterial vaginosis - Metronidazole
• Drug of choice for amoebic liver disease - Metronidazole
• Drug of choice for trichomoniasis - Metronidazole
• Drug of choice for giardiasis - Metronidazole
• Drug of choice for extraluminal amebiasis - Metronidazole
• Drug of choice for antibiotic-induced colitis - Metronidazole
• Drug of choice for anaerobic infections - Metronidazole
• Drug of choice for gonorrhea - Ceftriaxone
• Drug of choice for H.pylori eadication - Metronidazole
• Drug of choice for whooping cough - Erythromycin
• Drug of choice for cat scratch disease - Erythromycin
• Drug of choice for campylobacter infections – Erythromycin
• Drug of choice for fish tapeworm (Diphyllobothrium latum) - Praziquantel
• Drug of choice for dog tapeworm (Echinococcus granulosus) - Praziquantel
• Drug of choice for dwarf tapeworm (Hymenolepis nana) - Praziquantel
• Drug of choice for liver fluke (Fasciola hepatica) - Triclabendazole
• Drug of choice for blood fluke - Praziquantel
• Drug of choice for lung fluke - Praziquantel
• Drug of choice for community acquired pneumonia - Clarithromycin
• Drug of choice for surgical prophylaxis - Cefazolin
• Drug of choice for pneumocystis carnii - Cotrimoxazole
• Drug of choice for cholera in children - Cotrimoxazole
• Drug of choice for filarial worm- Di-Ethyl Carbamazepine
• Drug of choice for Platyhelminthes - Praziquantel
• Drug of choice for trichomoniasis - Metronidazole
• Drug of choice for extended spectrum bacterial lactamase - Carbapenem
• Drug of choice for otitis media - Amoxicillin
• Drug of choice for Nocardia - Sulfonamides
• Drug of choice for neurosyphilis - Aqueous penicillin
• Drug of choice for donovanosis - Azithromycin or Doxycycline
• Drug of choice for Neisseria - Ceftriaxone
• Drug of choice for Cryptococcus - For induction Amphotericin), for maintenance
(Fluconazole)
• Drug of choice for Neurocysticercosis - Albendazole
• Drug of choice for typhoid (Enteric fever) - LV Ceftriaxone
• First line drugs for tuberculosis - Rifampicin, Isoniazid, Pyrazinamide, Ethambutol,
Streptomycin (RIPES)
• Drug of choice for tuberculosis in renal failure - Rifampicin
• Drug of choice for prevention of tuberculosis in susceptible individuals - INH
• Drug of choice for treatment of tuberculosis in HIV positive patients taking protease
inhibitor – Rifabutin
• Drug of choice for MDR strains of tuberculosis - Amikacin
• Drug of choice for latent tuberculosis - INH
• Drug of choice for INH resistant patients of latent tuberculosis – Rifampin
• Drug of choice for leprosy - Rifampin
• Drug of choice for lepra 1 reaction - Glucocorticoids
• Drug of choice for lepra 2 reaction - Glucocorticoids
• Treatment of choice for multibacillary leprosy - Rifampin with Dapsone & Clofazimine
• Drug of choice for hot water born tuberculosis in hospital (M.xenopi) - Clarithromycin
• Drug of choice for cutaneous TB caused by atypical mycobacteria - Clarithromycin.
• Drug of choice for meningococcal prophylaxis - Ciprofloxacin
• Drug of choice for meningococcemia - Ceftriaxone
• Drug of choice for post splenectomy sepsis – Ceftriaxone
POISONING
o Drug of choice for paracetamol poisoning - N-Acetyl cysteine
o Drug of choice for organophosphate poisoning - Atropine
o Drug of choice for methotrexate toxicity - Folinic Acid
o Drug of choice for ethylene glycol poisoning - Fomepizole
o Drug of choice for warfarin poisoning - Vitamin K
o Drug of choice for heparin poisoning - Protamine sulphate
o Drug of choice for acute mercury - Dimercaprol
o Drug of choice for theophylline poisoning - Beta blockers
o Drug of choice for iron poisoning - Deferoxamine
o Drug of choice for copper poisoning - D-Penicillamine or Zinc acetate
o Drug of choice for acute arsenic poisoning - Dimercaprol
o Drug of choice for carbamate poisoning - Atropine
o Drug of choice for calcium channel blocker poisoning - Calcium with Glucagon
o Drug of choice for lead poisoning - DMSA
o Drug of choice for anticholinergic drug poisoning - Physostigmine
o Drug of choice for methylxanthines poisoning - Beta blocker
o Drug of choice for ergot alkaloid poisoning - Sodium nitroprusside
o Drug of choice for alpha 1 agonist poisoning – Phentolamine
o Drug of choice for beta 2 agonist poisoning - Propranolol
o Drug of choice for carbon dioxide poisoning - Hyperbaric oxygen
o Drug of choice for chronic mercury poisoning - N-acetyl- penicillamine
o Drug of choice for Beta blocker poisoning - Glucagon
o Drug of choice for antipsychotic poisoning - Sodium bicarbonate with lidocaine.
o Drug of choice for INH poisoning - Vitamine B6
o Drug of choice for cyanide poisoning - Amyl Nitrate
o Drug of choice for opiod overdose - Naloxone
o Drug of choice for aspirin poisoning - Vitamin K fresh frozen plasma
o Drug of choice for benzodiazepines poisoning - Flumazenil
o Drug of choice for iodine poisoning - Starch
RESPIRATORY SYSTEM
✓ Drug of choice for COPD - Anticholinergics (Eg:Tiotropium)
✓ First line drugs for tuberculosis - Rifampicin, Isoniazid, Pyrazinamide, Ethambutol,
Streptomycin (RIPES)
✓ Drug of choice for testing bronchial hyperactivity - Methacholine (Nonselective
muscarinic receptor agonist)
✓ Drug of choice for pulmonary edema with Congestive heart failure (CHF) -
Furosemide (Diuretic)
✓ Drug of choice for a vasodilatory shock - Norepinephrine
✓ Drug of choice for persistent hiccups - Carbon Dioxide
✓ Drug of choice for apnea in premature infants - Theophylline
✓ Drug of choice for exercise induced asthma - Mast cell stabilizers (Eg: Sodium
Cromoglycate)
✓ Drug of choice for asprin induced asthma - Leukotriene antagonist (Eg:
Montelukast)
✓ Drug of choice for starting treatment of asthma - Inhaled beta 2 agonists (Eg:
salmeterol)
✓ Drug of choice for bronchospasm with COPD - Ipratropium Bromide
✓ Drug of choice for smoking cessation - Nicotine
✓ Drug of choice for liquefying plaques of sputum in patients with cystic fibrosis -
Acetylcysteine
✓ Drug of choice for temporal arteritis - Corticosteroid
✓ Drug of choice for prophylaxis of exercise induced asthma - Sodium chromoglycate
✓ Drug of choice for pulmonary edema - Furosemide
✓ Drug of choice for dry itchy cough - Codeine
✓ Drug of choice for acute asthma attack - Salbutamol (Short acting Selective Beta2-
adrenergic receptor agonist)
✓ Drug of choice for persistent asthma - Inhaled corticosteroid
✓ Drug of choice for an asthmatic patient with hypertension - Amlodipine
✓ Drug of choice for Pneumocystis carinii - Cotrimoxazole
✓ Drug of choice for suppression of cough - Dextromethorphan
✓ Drug of choice for ACE inhibitor induced cough - Aspirin
✓ Drug of choice for asthma in diabetes - Ipratropium
✓ Drug of choice for beta blocker induced bronchospas - ipratropium bromide
✓ Drug of choice for mild persistent - Inhaled low dose corticosteroid or Mast cell
stabilizers or leukotrienes antagonist
✓ Drug of choice for moderate persistent asthma - Inhaled corticosteroid with long
acting beta 2 agonist
✓ Drug of choice for severe persistent asthma - High dose Inhaled corticosteroid
(ICS) + Long acting beta 2 agonists (LABA) + Oral corticosteroid
✓ Drug of choice for poorly controlled asthma - Theophylline
✓ Drug of choice for prophylaxis of asthma - Sodium cromoglycate (Mast cell
stabilizer)
✓ Drug of choice for paroxysmal supra-ventricular tachycardia (PSVT) - Adenosine
(Anti-arrhythmic agent)
✓ Drug of choice for supra-ventricular tachycardia (SVT) - Verapamil
✓ Drug of choice for digitalis-induced ventricular arrhythmia - Lignocaine (Anti-
arrhythmic agent)
✓ Drug of choice for ventricular arrhythmias - Lidocaine
✓ Drug of choice for ventricular tachycardia and fibrillation - Lidocaine
✓ Drug of choice for ventricular extra-systole - Beta blocker (Eg: Atenolol)
✓ Drug of choice for atrial fibrillation - Digitalis
✓ Drug of choice for maintaining sinus rhythm - Amiodarone (Antiarhythmic agent)
✓ Drug of choice for Wolff-Parkinson-white syndrome - Procainamide or Amiodarone
✓ Drug of choice for digitalis-induced arrhythmia - Lignocaine
✓ Drug of choice for acute left ventricular failure - 1.V Furosemide
✓ Drug of choice for the scleroderma induced hypertensive crisis - ACE inhibitors
✓ Drug of choice for acute long QT syndrome - MgSO4
✓ Drug of choice for congenital long QT syndrome - Beta blocker
✓ Drug of choice for hypertension with peripheral vascular disease - Calcium channel
blockers
✓ Drug of choice for the Hypertensive emergency - Sodium nitroprusside
(Vasodilator)
✓ Drug of choice for malignant hypertension - Nitroprusside (Vasodilator)
✓ Drug of choice for producing controlled hypotension - Sodium nitroprusside
✓ Drug of choice for pulmonary hypertension - Bosentan
✓ Drug of choice for atrial flutter and fibrillation - Ibutilide
✓ Drug of choice for paradoxical tachycardia - Digoxin (Digitalis glycosides)
✓ Drug of choice for angina - Nitrates (Vasodilator)
✓ Drug of choice for prophylaxis of stable angina - Beta blockers
✓ Drug of choice for variant angina - Calcium channel blockers (Eg: Verapamil)
✓ Drug of choice for the cardiogenic shock with renal failure - Dopamine
✓ Drug of choice for pulmonary edema with Congestive heart failure (CHF) –
Furosemide
CARDIOVASCULAR SYSTEM
➢ Drug of choice for digoxin toxicity - Potassium

➢ 1st line drug of choice for CHF- ACE inhibitors (Eg: Captopril,Enalapril)

➢ Drug of choice for rapid fast diuresis - Loop diuretics (Eg: Furosemide)

➢ Drug of choice for multi-focal atrial tachycardia - Verapamil (Calcium channel

blocker)-Furosemide (Loop diuretic)

➢ Drug of choice for rheumatic fever - Benzathine, Penicillin

➢ Drug of choice for TOF - Morphine

➢ Drug of choice for reducing mortility in CHF - Spironolactone

➢ Drug of choice for inotropic effect - Dobutamine

➢ Drug of choice for a hypertensive patient with benign prostatic hyperplasia (BPH) -

Alpha 1 Blocker (Eg: Prazosin, Terazosin, Doxazosin, Alfuzosin)

➢ Drug of choice for perioperative arrhythmias - Esmolol (Cardio selective beta

blocker)
URINARY SYSTEM
➢ Drug of choice for RPGN - Cyclophosphamide

➢ Drug of choice for lupus nephritis - Cyclophosphamide


➢ Drug of choice for nephrotic syndrome - Steroids

➢ Drug of choice for steroid-resistant nephrotic syndrome - Cyclosporine

➢ Drug of choice for steroid-dependent nephrotic syndrome - Cyclophosphamide


➢ Drug of choice for urinary retention - Bethanechol

➢ Drug of choice for enuresis - Imipramine

➢ Drug of choice for hemorrhagic cystitis - Mesna

➢ Drug of choice for patient allergic to thiazides and loop diuretics - Ethacrynic acid
➢ Drug of choice for forced alkaline diuresis - Furosemide

➢ Drug of choice for cerebral edema - Mannitol (Osmotic diuretic)

➢ Drug of choice for malignant hypertension - Furosemide

➢ Drug of choice for edema in liver cirrhosis - Furosemide


➢ Drug of choice for hypercalcemia - Furosemide (Loop diuretic)

➢ Drug of choice for edema in congestive heart failure - Furosemide

➢ Drug of choice for edema in renal failure - Furosemide

➢ Drug of choice for idiopathic hypercalciuria - Thiazide (Eg: hydrochlorothiazide)


➢ Drug of choice for calciuria due to hyperparathyroidism – Thiazides
➢ Drug of choice for nephrogenic diabetes insipidus - Thiazides

➢ Drug of choice for lithium induced nephropathy - Thiazides


➢ Drug of choice for hyperuricemia in renal failure - Allopurinol

➢ Drug of choice for gout in renal failure - Allopurinol

➢ Drug of choice for lesh nyhan syndrome - Allopurinol

➢ Drug of choice for urate nephropathy - Allopurinol (Xanthine oxidase inhibitor)


➢ Drug of choice for alkalization of urine - Acetazolamide
➢ Drug of choice for Conn's syndrome primary hyperaldosteronism - Spironolactone

➢ Drug of choice for secondary hyperaldosteronism - Spironolactone


➢ Drug of choice for thiazide induced hypoklemia - Spironlactone
OPTHALMOLOGY

• Drug of choice for open-angle glaucoma - Prostaglandins analogs

• Drug of choice for closed-angle glaucoma - Acetazolamide

• Drug of choice for secondary glaucoma - Beta blocker

• Drug of choice for inclusion conjunctivitis - Ceftriaxone

• Drug of choice for trachoma - Azithromycin

• Drug of choice for primary open angle glaucoma (POAG) - Timolol

• Drug of choice for Xerostomia - Cevimeline

• Drug of choice for corneal ulcer - Cyclopentolate

• Drug of choice for hypertension with glaucoma - Timolol

• Drug of choice for iridocyclitis - Atropine

• Which beta blocker is the drug of choice in open angle glaucoma - Timolol

• Drug of choice for hepatic keratitis - Idoxuridine

• Drug of choice for fungal corneal ulcer - Natamycin

• Drug of choice for uveal herpetic keratitis - Acyclovir

• Drug of choice for preventing meiosis during cataract surgery - Flurbiprofen

• Drug of choice for mild allergic conjunctivitis - Topical antihistaminic

• Drug of choice for decreasing intra ocular pressure before surgery - Osmotic diuretics
(Eg: Mannitol)

• Drug of choice for decreasing high intra ocular pressure - Osmotic diuretics

• Drug of choice for recurrent anterior uveitis - NSAID's

• Drug of choice for reducing intra ocular pressure in diabetes - Osmotic diuretics
ENDOCRINOLOGY
• Drug of choice lithium-induced diabetes mellitus - Amiloride

• Drug of choice for steroid-induced osteoporosis - Zolindrate (Bisphosphonates)

• Drug of choice for prostate cancer - GNRH Analogues (Eg: buserelin)

• Drug of choice for neurogenic diabetes insipidus - Desmopressin

• Drug of choice for nephrogenic diabetes insipidus - Thiazides

• Drug of choice for acute adrenal insufficiency - Hydrocortisone (I.V)

• Drug of choice for postprandial hyperglycemia - Nateglinide (Maglitinide derivative)

• Drug of choice for type 2 diabetes mellitus (DM) - Metformin (Bigunides)

• Drug of choice for type 1 diabetes mellitus (DM) - Regular Insulin

• Drug of choice for diabetes mellitus in pregnancy - Regular Insulin

• Drug of choice for uncontrolled diabetes mellitus - Regular Insulin

• Drug of choice for diabetic ketoacidosis - Regular Insulin

• Drug of choice for diabetes in renal and hepatic failure - Regular Insulin

• Drug of choice for diabetes in renal failure - Repaglinide (Maglitinide derivative)

• Drug of choice for prevention of breast cancer - Tamoxifen

• Drug of choice for prevention of diabetes - Metformin

• Drug of choice for severe hypoglycemia in case of insulinoma - Diazoxide (Potassium


channel opener)

Drug of choice for emergency contraception - Mifepristone

• Drug of choice for polycystic ovarian disease - Clomiphene citrate

• Drug of choice for oligospermia - Clomiphene citrate

• Drug of choice for corpus luteum insufficiency - Clomiphene citrate

• Drug of choice for anovulatory infertility - Clomiphene citrate

• Drug of choice for post coital contraception - Mifepristone

• Drug of choice for hirsutism - Cyproterone acetate (Androgen receptor antagonist)

• Drug of choice for large prostate - Finasteride (5 alpha reductase inhibitor)

• Drug of choice for inducing labour - Oxytocin


• Drug of choice for BPH - Tamsulosin

• Drug of choice for postmenopausal osteoporosis - Raloxifene or Bisphosphonates

• Drug of choice for acute & chronic adrenal insufficiency - Hydrocortisone (Shortest
acting glucocorticoid)

• Drug of choice for congenital adrenal hyperplasia - Hydrocortisone

• Drug of choice for tumor induced brain edema - Dexamethasone (Long acting
glucocorticoid)

• Drug used for mineralocorticoid replacement - Fludrocortisone

• Drug of choice for Premenstrual syndrome - SSRI'S (Eg: Fluxetine)

• Drug of choice for dysfunctional uterine bleeding - NSAIDS

• Drug of choice for androgenic alopecia - Finasteride (5 Alpha reductase inhibitor)

• Drug of choice for hypothyroidism - Levothyroxine

• Drug of choice for hypothyroidism in children (cretinism) - Thyroxine

• Drug of choice for myxedema coma - Levothyroxine

• Drug of choice for reducing thyroid gland vascularity - Potassium iodide

• Drug of choice for hyperprolactinemia - Bromocriptine

• Drug of choice for acute gout - NSAID (Indomethacin)

• Drug of choice for chronic gout - Allopurinol (Xanthine oxidase inhibitor)

• Drug of choice for thyroid storm - Propylthiouracil

• Drug of choice for making patient euthyroid before surgery - Potassium iodide

• Drug of choice for thyroid cancer - Levothyroxine

• Drug of choice for grave's disease - Methimazole (Antithyroid drug)

• Drug of choice for thyroid ablation - 1 131

• Drug of choice for thyroid storm in India - Potassium iodide

Drug of choice for reducing somatic manifestations of hyperthyroidism - Propranolol

• Drug of choice for diabetic ketoacidosis (DKA) - Regular Insulin

• Drug of choice for pheochromocytoma - Phenoxybenzamine (Alpha blocker)

• Drug of choice for acute hypercalcemia - Furosemide (Loop diuretic)

• Drug of choice for hypercalcemia due to malignancy – Bisphosphonate


PREGNANCY
Drug of choice for ectopic pregnancy-Methotrexate
Drug of choice for induction of labor - Oxytocin
Drug of choice for postpartum hemorrhage - Oxytocin
Drug of choice for hypertension in pregnancy - Alpha Methyldopa
Drug of choice for endometriosis - Danazol
Drug of choice for asthma - Beta 2 agonists
Drug of choice for postpartum breast engorgement - Oxytocin
Drug of choice for seizures in eclampsia - Magnesium sulphate
Drug of choice in seizures during pregnancy-Phenobarbitone
Drug of choice for the hypertensive emergency in pregnancy - Labetalol
Drug of choice for postpartum hemorrhage - Oxytocin
Drug of choice for falciparum malaria in pregnancy - Quinine.
Drug of choice for cerebral malaria - Quinine
Drug of choice for gonorrhea - Penicillin or Ceftriaxone
Drug of choice for toxoplasmosis in pregnancy - Spiramycin
Drug of choice for malaria in pregnancy - Chloroquine
Drug of choice for acne - Erythromycin (oral) / Benzylbenzoate (Topical)
Drug of choice for epilepsy in pregnancy - Phenobarbitone
Drug of choice for mania in pregnancy - Olanzapine
Drug of choice for hyperthyroidism - Propylthiouracil
Drug of choice for hypothyroidism - Levothyroxine
Drug of choice for bacterial vaginosis in 1st trimester - Clindamycin
Drug of choice cholera in pregnancy – Furazolidone
Drug of choice for severe erythrodermic psoriasis - Cyclosporine
Drug of choice for pustular psoriasis - Retinoid
Drug of choice for impetigo herpetiformis - Systemic Steroids
Drug of choice for dermatitis herpetiformis - Dapsone
Treatment of choice for subacute eczema - Creams & Moisturizers
Treatment of choice for chronic eczema - Ointment
Drug of choice for impetigo - Mupirocin
Drug of choice for solar lentigenes - Tretinoin
Drug of choice for chancroid - Ceftriaxone
Drug of choice for pemphigus vulgaris - Prednisolone
Drug of choice for vitiligo - Corticosteroids
Drug of choice for atopic dermatitis - Topical corticosteroids
Drug of choice for severe excerebation of atopic dermatitis - Systemic
corticosteroids
Drug of choice for reducing recurrence of melanoma - Alpha interferon with
vaccine
Drug of choice for lichen simplex chronicus - Corticosteroids
Drug of choice for seborrhic dermatitis in scalp - Selenium shampoo
Drug of choice for acne rosacea - Oral tetracycline
Drug of choice for tinea capitis - Griseofulvin
Drug of choice for the scleroderma induced hypertensive crisis - Ace inhibitors
(Eg:Captopril, Enapril etc)
Treatment of choice for lichen planus - Topical glucocorticoids
Drug of choice for systemic dermatophytosis – Griseofulvin
Drug of choice for typhoid fever in pregnancy - Ceftriaxone or Ampicillin
Drug of choice for amoebiasis - Metronidazole (Contraindicated in 1st trimester)
Drug of choice for amoebiasis in 1st trimester - Furazolidone
Drug of choice for preventing neural tube defect - Folic acid
Drug of choice for anticoagulation in pregnancy - Heparin
Drug of choice for mania - Lithium
Drug of choice for myasthenia gravis - Neostigmine
Drug of choice for thrombophlebitis - Aspirin
Drug of choice for urinary tract infection during pregnancy - Ampicillin
Drug of choice for HIV in pregnancy - Zidovudine and Nevirapine
Drug of choice for resistant typhoid - Ceftriaxone
Drug of choice for tuberculosis - INH with rifampicin
Drug of choice for vitamin B12 deficiency - Cyanocobalamin
Drug of choice for iron deficiency - Ferrous sulphate
Drug of choice for antiplatelet action - Aspirin
Drug of choice for anxiety - Benzodiazepines
Drug of choice for pain - Aspirin / Paracetamol
Drug of choice for depression in pregnancy - Tricyclic antidepressant
Drug of choice for superficial thrombophlebitis - Aspirin
Drug choice for bacterial vaginosis in 1st trimester in pregnancy - Clindamycin
Drug choice for rosacea - NSAIDS
Drug choice for rheumatoid arthritis - Aspirin
Drug choice for schizophrenia - Phenothiazines (Eg: Haloperidol)
Drug choice for seborrheic dermatitis - Salicylic acid
DERMATOLOGY
▪ Drug of choice for taenia - Topical azoles (Eg: clotrimazole)
▪ Drug of choice for erythrodermic psoriasis - Methotrexate
▪ Drug of choice for psoriatic arthropathy - Methotrexate
▪ Drug of choice for severe psoriasis – Methotrexate

PASALAMAT MO NAKO KAPOY KAYG


TYPE MGA HINAMPAK SAY THANK YOU
MASTER, MUDAWAT RASAD KOG UYAB.

KENT ANDREI P. PAELMA

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