Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
LESSON PLAN FOR DEMONSTRATION TEACHING
4A’s Instructional Strategies
Teacher EANNA B. NAKILA
Learning Area SCIENCE
Grade & Section Grade 10- Mendeleev
Date Feb, 2024
Time 7:45-8:45 AM
I. OBJECTIVES
A. Content Mutations that occur in sex cells as being heritable
Standards
B. Performance
Standards
C. Learning Explain how mutations may cause changes in the structure and function
Competencies of a protein
D. Objectives 1. Distinguish the types of mutations
2. Differentiate the kinds of chromosomal mutations by group, and
3.Evaluate the impact of COVID-19 mutations on the pandemic
emphasizing the importance of adaptive strategies in public health.
Code S10LT-IIIe-38
II. CONTENT Mutations
III. LEARNING RESOURCES
A. References
1. Teacher’s Guide WLAS Week 4
Pages
2. Learner’s WLAS pp. 1-8
Material Pages
3. Textbook Pages Science 10 book
4. Additional
Materials from None
Learning
Resources
B. Other Learning
Resources Books
IV. PROCEDURES
Teacher’s Activity Students’ Activity
A.Preliminaries
Good morning class! Good morning, ma’am Nakila!
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
Please arrange your chairs and
settle down for we are about to start
our discussion.
a. Prayer
Before anything else, may I request
everyone to please stand. Let us
pray first.
Let us bow down our heads and
pray…
Amen.
Please be seated.
(the students take their
respective seats)
b. Classroom Rules
But before we begin, let me remind
you first of our classroom rules that
you all need to follow.
1. Respect your teacher and also
your fellow classmates.
2. Be attentive and learn to listen
especially when someone is
speaking in front.
3. If you have questions or
clarifications, just raise your hand.
understood?
Good. I hope that you will all obey
Yes, ma’am!
B. Review
Before we start our new lesson, who
among you here can recall our
previous topic?
We talk about DNA and RNA
ma’am.
Yes, Very good! So what is DNA?
DNA, or deoxyribonucleic acid, is
a molecule that carries the
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
genetic instructions used in the
growth,development, functioning,
and reproduction.
Very good! What about RNA?
RNA, or ribonucleic acid, is a
molecule that plays a crucial role
in various cellular processes,
particularly in the synthesis of
proteins. Like DNA, RNA is a
nucleic acid, but it has a single-
stranded structure.
Very good! I’m glad that you can still
remember our previous discussion.
C. Motivation Class, before we delve into our new
lesson, are you familiar with
superheroes?
Yes, ma’am!
Of course you do right? Whether
from your childhood or even up to
this day, you have a fondness for
superheroes.
So I have here some images of your
most favorite characters or
superheroes, as we call them. I want
you to guess who they are and what
strength or power they have.
(Students enthusiastically named
all the pictures shown)
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
Now, in connection of our previous
discussion, what do you think our
next topic will be?
I think our topic will be all about
mutations, ma’am.
Alright, good guess! Let’s discover
that later and find out what our next
topic will be.
D. Activity
But before we finally discover our
new lesson, let’s familiarize
ourselves first with some challenging
words that we may encounter during
our discussion.
Instructions: Read the questions
carefully. Encircle the letter of the
correct answer. ANSWERS:
1. The company announced its plans 1. A
for expansion into new international
markets.
a. Increase
b. Constriction
c. Reduction
2. She visits the library frequently to 2. B
borrow books for her research.
a. Seldom
b. Repeatedly
c. Occasionally
3. The old toy had a deformed 3. B
shape, with missing parts and a
twisted structure.
a. Normal
b. Misshapen
c. Regular
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
4. The quality control team identified 4. C
several defects in the manufacturing
process, leading to product recalls.
a. Perfections
b. Strengths
c. Flaws
5. The artist created an interesting 5. A
piece with an inverted color scheme,
turning the traditional colors into their
opposites.
a. Upside-down
b. Straight
c. Upright
E. Analysis 1. What is mutation?
It is a permanent change in the
DNA arrangement of a gene.
2. What are the two general
types based on the ranges in
size from a single DNA?
The DNA mutations and the
chromosomal mutations.
3. How do we get mutations?
Mutations can be inherited and
acquired.
4. How do we know whether that
mutation is good or bad? There are good mutations but
also it can be harmful to any
organism’s genome.
5. How about the syndromes?
How can we avoid them? The best way to avoid those
syndromes, see a doctor three
months before you try to have a
baby, do not smoke or drink
alcohol.
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
E. Abstraction Let’s have another activity entitled
“Who am I?”
Direction: Choose your answer from
the box and answer the guide
question.
ANSWERS:
1. I am the type of mutation in which 1. FRAMESHIFT MUTATION
the DNA bases are changed due to
either loss or addition of DNA bases
resulting to the change of the gene’s
reading frame. Who am I?
2. I am the type of mutation in which 2. DELETION
section of DNA is lost, or deleted?
Who am I?
3. I am the type of mutation that 3. MISSENSE MUTATION
changes one DNA base pair (like A
is changed to C) that result in the
substitution of one amino acid for
another in the protein made gene.
Who am I?
4. I am the type of mutation that 4. INSERTION
changes the number of DNA bases
in a gene by adding a piece of DNA.
Who am I?
5. I am the type of mutation in which 5. NONSENSE MUTATION
the DNA is abnormally copied one or
more times. Who am I?
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
F. Application
Let’s have another activityentitled
Fill Me!
Directions: Copy the graphic
organizer below and fill in the
definiton in one sentence of the
different kinds of chromosomal
mutations. An example is given as
your guide.
We are facing the pandemic due to
the Corona Virus Disease or the
COVID-19 which affect all of us. For
over a year, the said virus had
mutated which results to a new strain
or variant. Explain why the said virus
has a new variant?
Viruses mutate. Multiple variants
have recently made headlines,
including a UK variant, Brazilian
variant and some others, some
emerging variants are believed to
be transmissible.
Very well said!
G. Assessment
Let’s proceed to your final activity!
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
Direction: Read and analyze each
sentence. Choose the letter of the
correct answer. ANSWERS:
1. Extra fingers or toes, deformed 1. A
feet, small eyes, absent or
malformed nose, small head failure
of the brain to divide severe mental
deficiency, heart and kidney defects.
a. Patau Syndrome
b. Edwards Syndrome
c. Down Syndrome
2. No human can survive without an 2. B
X chromosome.
a. Jacobs Syndrome
b. Lethal
c. Poly-X female
3. Female, tall, thin, longer face or 3. C
jaw, delayed language development,
higher incidence of dyslexia, mild to
moderate mental impairmnet.
a. Klinefelter Syndrome
b. Lethal
c. Poly-X female
4. Decreased muscle tone, stockier 4. B
build, asymmetrical skull, slanting
eyes, and mild to moderate mental
retardation.
a. Edwards Syndrome
b. Down Syndrome
c. Patau Syndrome
5. Low birth weight, small jaw and 5. C
mouth, small and abnormally shaped
head, overlapping fingers and
Republic of the Philippines
Department of Education
Caraga Administrative Region
Division of Agusan del Norte
TUBAY II District
DOŇA NATIONAL HIGH SCHOOL
clenched fists, have defects in the
heart and other organs.
a. Wolf-Hirschhorn Syndrome
b. Jacobsen Syndrome
c. Edwards Syndrome
H. Agreement Please do advance reading the
evidence of evolution.
1. What are fossils?
2. How do we distinguish
homologous structure from an
analogous structure?
