Document 9
Document 9
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
• Gregor Mendel proposed laws of inheritance in living organisms to
Th
is
provide details about inheritance patterns.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• For studying pattern typical monohybrid cross, Punnett square are
Th
is
used which were developed by R.C. Punnett.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• The results from experiments of G. Mendel were rediscovered by
Th
is
Hugo de Vries, Correns & von Tschermark independently in 1900.
PD
F
be
lo
ng
They were able to see process of cell division due to developments
s
to
M
ad
ih
in field of microscopy.
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Chromosomal theory of inheritance was given by Sutton & Boveri in
Th
is
year 1902. Walter Sutton & Theodore Boveri demonstrated that the
PD
F
be
lo
ng
process of pairing & separation of a pair of chromosomes would
s
to
M
ad
ih
eventually result in the segregation of a pair of factors they carried.
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Chromosome or genetic map were first discovered by Alfred
Th
is
Sturtevent who prepared these maps based on distance between
PD
F
be
lo
ng
genes present on the chromosomes .
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Experimental work on Drosophila to study linkage and crossing over
Th
is
was extensively done by Thomas Hunt Morgan who is also known
PD
F
be
lo
ng
as Father of Experimental genetics. He studied physical association
s
to
M
ad
ih
or linkage of the two genes and later coined the term ‘linkage’ to
a@
78
6
(m
ad
describe this physical association of genes on a chromosome and
i
ha
sh
ai
k
h2
90
the term recombination to denote generation of non-parental gene
5@
gm
ai
l.c
combinations
om
,9
00
43
66
53
6)
• Henking trace a specific nuclear structure (X-body) all through
Th
is
spermatogenesis in a few insects (1891).
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Discovery of autosomal disorder Down's syndrome was done by
Th
is
Langdon Down (1866)
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• DNA (Nuclein) was first identified by Friedrich Meischer (1869).
Th
is
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
6)
53
66
43
00
,9
om
X-ray diffraction data produced by Wilkins & Franklin.
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
• Watson study on the "Effect of hard X-rays on bacteriophage
Th
is
multiplication" (1950)
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
Transforming principle was given by Griffith (1928).
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
• Biochemical characterisation of transforming principle was given by
Th
is
Avery, MacLeod & Mc Carty.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Unequivoal proof that DNA is the genetic material came from the
Th
is
experiments of Hershey & Chase (1952).
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
Replication scheme was given by Watson & Crick.
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
• The experimental proof that DNA replicates semiconservatively was
Th
is
given in prokaryotes by Meselson & Stahl (1958).
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• The experimental proof that DNA replicates semiconservatively was
Th
is
given in eukaryotes by Taylor (1958).
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
Central dogma of biology was given by Crick.
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
George Gamow (a physicist) proposed that codon was triplet.
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
• Har Go bind Khorana synthesizes RNA molecules with de fined
Th
is
combination of bases (homopolyers & copolymers).
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Nirenberg in cell-free system for protein synthesis finally helped the
Th
is
code to be deciphered.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
Polynucleotide phosphorylase is called Severo Ochoa enzyme
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
• To study gene expression in prokaryotes, Lac operon was given by
Th
is
Jacob & Monad.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Automated DNA sequencers worked on the principle of a method
Th
is
developed by Frederick Sanger
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Frederick Sanger developed the method for determination of amino
Th
is
acid sequences in proteins.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
DNA fingerprinting technique was developed by Alec Jeffreys.
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
Spontaneous generation theory was dismissed by Louis Pasteur.
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
Life comes from pre -existing life it is told by Louis Pasteur.
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
• A.I Oparin and J.B.S Haldane proposed Oparin-Haldane Theory of
Th
is
Origin of Life that showed that life could have originated from pre-
PD
F
be
lo
ng
existing non-living organic molecules/chemicals.
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• S.L Miller – the famous Miller experiment to demonstrated origin of
Th
is
life. Atmosphere of Earth was created in lab with use of methane,
PD
F
be
lo
ng
water, hydrogen, and ammonia which were held in closed flask
s
to
M
ad
ih
apparatus.
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Use and disuse of organs' theory of evolution was given by Lamarck
Th
is
(French Naturalist).
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Charles Darwin worked immensely on concept of Natural Selection
Th
is
and he had shown that it is natural selection that had worked as a
PD
F
be
lo
ng
mechanism for evolutionary process. He made a sea voyage in ship
s
to
M
ad
ih
with name H.M.S. Beagle around the globe.
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Naturalist Alfred Wallace who was also emphasized on natural
Th
is
selection (for evolution of life ) worked in Malay Archipelago.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
Malthus work on population.
•
• Hugo de Vries brought forth the idea of mutations. Hugo de Vries
Th
is
used the term saltation.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
support
·
• Embryological
Hugo de Vries brought forth the idea of mutations. Hugo de Vries
Th
is
used the term saltation.
for evolution:
PD
F
!
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
eckel
ad
Ernst
i
ha
sh
1.
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
Baer
53
6)
Von
2. Karl Ernet
dismiss
->
•
⑧
Hardy Weinbergy
Hugo de Vries brought forth the idea of mutations. Hugo de Vries
--
Th
is
used the term saltation.
PD
F
be
lo
ng
frequency of
s
to
occurence
M
->
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
of gene
k
h2
allele a
90
of
5@
an
gm
ai
l.c
population.
om
,9
00
43
fixed
66
in
53
an
6)
is
dominant-p
of allele
Frequency
->
allele:g
Frequency of
- receive
p g1
+ =
• Short-duration high-yielding varieties of rice (including scented
Th
is
Basmati) was developed by M.S. Swaminathan.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Norman Borlaug - Semi-dwarf wheat at ICWMI were developed by
Th
is
Norman Borlaug.
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
Fleming
-
•
At
Norman
-
Borlaug - Semi-dwarf wheat at ICWMI were developed by
Th
is
Norman Borlaug.
PD
F
be
lo
ng
s
to
M
Antibiotic
ad
Ist
ih
a@
78
6
(m
ad
-
i
ha
willin
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
-
would Penicillium
-
notature
-
• Herbert Boyer observed that the restriction enzymes have the
Th
is
capability of cutting DNA strands in a particular fashion (1969).
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
6)
53
66
Ramdeo Misra revered as the father of ecology in India.
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
6)
53
66
43
00
"Competitive Exclusion principle" was given by Gause.
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
Concept of Resource partitioning was put forward by Mac Arthur.
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
Cost of ecosystem services was given by Robert Costanza.
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
Term Biodiversity popularised by Edward Wilson (Sociobiologist)
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
Species-area relationship was given by Alexander von Humboldt.
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
• The importance of species diversity to the ecosystem was given by
Th
is
David Tilman
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
• Rivet popper hypothesis was given by Paul Ehrlich (Stanford
Th
is
Ecologist)
PD
F
be
lo
ng
s
to
M
ad
ih
a@
78
6
(m
ad
i
ha
sh
ai
k
h2
90
5@
gm
ai
l.c
om
,9
00
43
66
53
6)
6)
53
66
43
00
,9
om
l.c
ai
Polyblend is formed by Ahmed Khan & his company.
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th
•
6)
53
66
43
00
,9
om
l.c
ai
gm
5@
90
k h2
ai
sh
iha
ad
(m
6
78
a@
ih
ad
M
to
s
ng
lo
be
F
PD
is
Th