Name: _____________________________ Date: _________________
Course/Section: _____________________ Score: ________________
Test I. Multiple Choice
Instruction: Choose the best answer and write the letter of your correct answer on the blank
provided. USE CAPITAL LETTER TO WRITE YOUR ANSWER.
___1. It explores chemical processes related to living organisms
a. Chemistry c. Biology
b. Biochemistry d. Organic Chemistry
___2. What aspect of Biochemistry have different biomolecules which comprise the cell?
a. pH and buffers c. Molecular anatomy
b. Molecular Biochemistry d. Molecular Physiology
___3. The study of macromolecules and their metabolic activities in the body includes the entrance
in the human body, digestion, absorption, assimilation, utilization, and integration into the tissues,
metabolic degradation and eventually excretion from the body.
a. pH and buffers c. Molecular anatomy
b. Molecular Biochemistry d. Molecular Physiology
___4. This is the dynamic part of Biochemistry which includes the functions and metabolic activities
of biomolecules in the cell.
a. pH and buffers c. Molecular Anatomy
b. Molecular Biochemistry d. Molecular Physiology
___5. What are those electrolytes that dissociate or are ionized completely in their aqueous
solution?
a. Strong Electrolytes c. Non-Electrolytes
b. Weak Electrolytes d. Electrolytes
___6. A compound that does not conduct an electronic current in either aqueous solution or in the
molten state.
a. Strong Electrolytes c. Non-Electrolytes
b. Weak Electrolytes d. Electrolytes
___7. What electrolyte substances that have a natural positive or negative electrical change which
dissolved in water?
a. Strong Electrolytes c. Non-Electrolytes
b. Weak Electrolytes d. Electrolytes
___8. A condition in the course of a reversible chemical reaction in which no net change in the
amounts of reactants and products occurs.
a. Chemical Equilibrium c. Irreversible reaction
b. Electrolytes d. Reversible reaction
___9. Which reaction in the conversion of reactants to products and the conversion of products to
reactants occur simultaneously?
a. Chemical Equilibrium c. Irreversible reaction
b. Electrolytes d. Reversible reaction
___10. Which reactants are converted to products but the products cannot be converted back to
reactants?
a. Chemical Equilibrium c. Irreversible reaction
b. Electrolytes d. Reversible reaction
___11. What is the normal blood pH?
a. 7.40 to 7.45 c. 7.30 to 7.45
b. 7.35 to 7.45 d. 7.45 to 8.00
___12. A condition in which there is too much acid in the body fluids.
a. Acidosis c. Gaseous Acidosis
b. Alkalosis d. Renal Acidosis
___13. A condition in which there is too much base in the body fluids.
a. Acidosis c. Gaseous Acidosis
b. Alkalosis d. Renal Acidosis
___14. A condition that occurs when your lungs can’t remove all of the carbon dioxide produced by
your body.
a. Gaseous Acidosis c. Renal Acidosis
b. Respiratory Acidosis d. Metabolic Acidosis
___15. The buildup of acid in the body due to kidney disease or kidney failure is called?
a. Gaseous Acidosis c. Renal Acidosis
b. Respiratory Acidosis d. Metabolic Acidosis
___16. A kidney failure results in excessive loss of bicarbonate or retention of phosphoric and
sulfuric acids.
a. Gaseous Acidosis c. Renal Acidosis
b. Metabolic Alkalosis d. Metabolic Acidosis
___17. A more than the normal amount of CO2 is retained in the body.
a. Gaseous Acidosis c. Respiratory Alkalosis
b. Metabolic Alkalosis d. Metabolic Acidosis
___18. The test that performed before obtaining an arterial blood specimen from the radial artery to
determine the presence of collateral circulation and the adequacy of the ulnar artery.
a. Alka Test c. ROME test
b. Joey’s test d. Allen’s test
___19. It causes excessive loss of gastric HCl due to persistent vomiting or severe vomiting or the use
of diuretics except acetalozamides.
a. Metabolic Acidosis c. Respiratory Acidosis
b. Metabolic Alkalosis d. Respiratory Alkalosis
___20. Produced by hyperventilation (salicylate poisoning or artificial respirator) which lowers the
CO2 level of the blood.
a. Metabolic Acidosis c. Respiratory Acidosis
b. Metabolic Alkalosis d. Respiratory Alkalosis
II. Solving Problem (10 points)
Instruction: Calculate the values of both pH and pOH of the following solutions
pH pOH
a. 0.0235 M HCl
b. 6.2 x 10-5 M NaOH
c. A blood sample 7.2 x 10-
8
M of H+
d. 0.00035 M KOH
e. 6.50 x 10-3 M KOH
III. Identification Test
Instruction: Identify what is being asked on the following question. Write your answer on the space
provided.
____________________1. It is a white crystalline substance that is soluble in water, except cysteine
and tyrosine which are more soluble in hot water.
____________________2. This is the principle involved in ________ method for determining amino
groups in proteins, blood and other biological substances.
____________________3. It’s when an excess of neutral formaldehyde is added to neutral amino
acid solution, a distinctly acid mixture is produced.
____________________4. The amino group is previously protected by ________.
____________________5. When amino acids are dehydrated, they unite with each other forming a
ring, ___________.
____________________6. This has been widely studied for its effect in raising the general
intelligence level of subnormal patients and used for the treatment of psychomotor and petit mal
attacks.
____________________7. The simplest amino acid and has is sweet in taste.
____________________8. Made up of protein molecules combined with non-protein groups.
____________________9. Insoluble substances resulting from the preliminary action of water,
dilute acids or enzymes.
____________________10. Not coagulated by heat and not precipitated by saturation with
ammonium sulfate but by certain alkaloidal reagents such as phosphotungstic and tannic acids.
IV. Modified True or False
Instruction: Write TRUE if the statement is correct, and if it is FALSE change the underlined word to
make the statement correct.
__________1. Amino acids are ampholyte due to the presence of both carboxyl and amino group. As
such they form crystalline salts with metallic bases and with mineral acids.
__________2. Globulins are coagulated by heat and can be precipitated from their solutions by half
saturation with (NH4)2SO4 and complete saturation with NaCl.
__________3. Two amino acid molecules can be covalently joined through a substituted amide
linkage, termed a peptide bond, to yield a dipeptide. Such a linkage is formed by a removal of the
elements of water (dehydration) from the alpha carboxyl group of one amino acid and the alpha-
amino group of another.
_________4. Left handed alpha helix is rare, because amino acids found in proteins are of L-variety,
which exclude left handedness.
________5. Tertiary Structure is the most complex aspect of protein strand.
________6. Calmodulin is the term used to denote a compact globular functional unit of a protein.
________7. The arrangements of the tertiary structure elements in a protein form a “fold”. A typical
example is domain, the calcium binding regulatory protein which regulates intracellular calcium
level.
_______8. Alcohol can be used to disrupt hydrogen bonds and non-polar hydrophobic interactions.
This occurs because heat increases the kinetic energy and causes the molecules to vibrate so rapidly
and violently that the bonds are disrupted.
_______9. Strong acids and bases change the pH of the solution containing proteins and therefore
change the ionization of acidic and basic side chains, leading to disruption of ionic bonds.
______10. Detergents are amphipatic in nature and proteins have hydrophobic and hydrophilic
sides, the detergent is attracted to these and forces the protein apart and denatures the proteins.
Prepared by:
Quileste, Desiree Jane V.
Monsanto, Cyril Nicole F.
